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Tag Content
iUUCD ID IUUC-Dre-028646
Ensembl Protein ID ENSDARP00000045092.7
UniProt Accession F1QMD3; F1QMD3_DANRE
Genbank Protein ID ENSDARP00000045092
Protein Name Rho guanine nucleotide exchange factor (GEF) 7a
Genbank Nucleotide ID BX649266
Gene Name arhgef7a
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000006299.10 ENSDART00000141408.2 ENSDARP00000121774.1
ENSDARG00000006299.10 ENSDART00000045093.7 ENSDARP00000045092.7
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 7.80e-15 55.5 167 221
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deLt+ kGd + v    ++++gW++g   l+gk G fP+n+v++++
   Q: 167  VVKARFNFQQTNEDELTFSKGDLISVT--RTEEGGWWEG--ILNGKTGWFPSNYVKEVK 221
           6999**********************7..999*******..8**************996 PP
   
Organism Danio rerio
Protein Sequence
(Fasta)
MNPAEQTVTW LITLGVLESP KKTISDPDGF LQASLKDGVV LCRLLERLRP GTTDKIIQDP 60
KNDSECLSNI TEFLKGCAVF RVEPFEAGDL LQGHNISRVL TTLVALNKVT ADIGIGSDSV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-028646|UBD,SH3|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ACTGCGCTGT GACTGTATTC CAGTGAAAGG CGTTTGACAG CTTGTCGGAA TAAAAGGAAA 60
TGGGAGCGAA GCGATAGCAT TACTCATCTC CATGGAGCGC CGTATAACGA GCCATCCTTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028646|UBD,SH3|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain
PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3
Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00621--RhoGEF
PF14604--SH3_9
PRINTS

PR00452--SH3DOMAIN
SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3
Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001259 Ailuropoda melanoleuca 72.05 0.00e+00 1028.00
IUUC-Aca-004591 Anolis carolinensis 74.51 0.00e+00 1143.00
IUUC-Ame-010759 Astyanax mexicanus 88.18 0.00e+00 1506.00
IUUC-Bta-013328 Bos taurus 73.35 0.00e+00 1195.00
IUUC-Cja-018742 Callithrix jacchus 74.89 0.00e+00 943.00
IUUC-Cfa-020756 Canis familiaris 65.43 0.00e+00 916.00
IUUC-Cpo-021284 Cavia porcellus 73.14 0.00e+00 1126.00
IUUC-Csa-023162 Chlorocebus sabaeus 74.97 0.00e+00 1207.00
IUUC-Cho-024736 Choloepus hoffmanni 72.78 6.00e-72 265.00
IUUC-Cin-025535 Ciona intestinalis 42.26 4.00e-94 338.00
IUUC-Dno-029461 Dasypus novemcinctus 74.86 0.00e+00 1211.00
IUUC-Dor-030623 Dipodomys ordii 64.68 0.00e+00 826.00
IUUC-Ete-032236 Echinops telfairi 62.12 4.00e-179 621.00
IUUC-Eca-034137 Equus caballus 74.29 0.00e+00 1067.00
IUUC-Fca-035742 Felis catus 65.34 0.00e+00 889.00
IUUC-Fal-037205 Ficedula albicollis 76.03 0.00e+00 989.00
IUUC-Gmo-039475 Gadus morhua 71.25 0.00e+00 1091.00
IUUC-Gga-040539 Gallus gallus 68.27 0.00e+00 862.00
IUUC-Gac-042615 Gasterosteus aculeatus 70.93 0.00e+00 1032.00
IUUC-Ggo-044470 Gorilla gorilla 71.63 0.00e+00 1023.00
IUUC-Hsa-046398 Homo sapiens 73.43 0.00e+00 1059.00
IUUC-Loc-052146 Lepisosteus oculatus 79.81 0.00e+00 1306.00
IUUC-Laf-053891 Loxodonta africana 71.46 0.00e+00 1174.00
IUUC-Mcc-055483 Macaca mulatta 72.92 0.00e+00 1058.00
IUUC-Mga-059410 Meleagris gallopavo 74.06 0.00e+00 1088.00
IUUC-Mmr-060758 Microcebus murinus 75.29 0.00e+00 1030.00
IUUC-Mdo-061900 Monodelphis domestica 65.97 0.00e+00 1043.00
IUUC-Mmu-063849 Mus musculus 75.16 0.00e+00 1048.00
IUUC-Mpu-065876 Mustela putorius furo 65.13 0.00e+00 908.00
IUUC-Mlu-067970 Myotis lucifugus 74.68 0.00e+00 1075.00
IUUC-Nle-069685 Nomascus leucogenys 64.87 0.00e+00 883.00
IUUC-Opr-071132 Ochotona princeps 51.16 3.00e-159 555.00
IUUC-Ont-071815 Oreochromis niloticus 80.86 0.00e+00 1350.00
IUUC-Oan-073057 Ornithorhynchus anatinus 74.75 0.00e+00 999.00
IUUC-Ola-086663 Oryzias latipes 78.71 0.00e+00 1159.00
IUUC-Oga-088103 Otolemur garnettii 74.20 0.00e+00 1034.00
IUUC-Ptr-091162 Pan troglodytes 71.72 0.00e+00 959.00
IUUC-Pan-092093 Papio anubis 68.81 0.00e+00 1123.00
IUUC-Pfo-096736 Poecilia formosa 75.32 0.00e+00 1217.00
IUUC-Pab-097641 Pongo abelii 66.44 0.00e+00 1040.00
IUUC-Pva-102819 Pteropus vampyrus 72.19 0.00e+00 1008.00
IUUC-Rno-106099 Rattus norvegicus 74.74 0.00e+00 1179.00
IUUC-Sha-106845 Sarcophilus harrisii 64.58 0.00e+00 912.00
IUUC-Ssc-116036 Sus scrofa 64.03 0.00e+00 892.00
IUUC-Tgu-117498 Taeniopygia guttata 72.31 0.00e+00 1151.00
IUUC-Tru-118278 Takifugu rubripes 78.49 0.00e+00 1177.00
IUUC-Tsy-118990 Tarsius syrichta 71.89 0.00e+00 754.00
IUUC-Tni-120852 Tetraodon nigroviridis 73.43 0.00e+00 1163.00
IUUC-Ttr-128922 Tursiops truncatus 68.71 0.00e+00 886.00
Created Date 25-Jun-2017

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