iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000010303.2	ENSMLUT00000028769.1	ENSMLUP00000022158.1
ENSMLUG00000010303.2	ENSMLUT00000010354.2	ENSMLUP00000009437.2
ENSMLUG00000010303.2	ENSMLUT00000010366.2	ENSMLUP00000009449.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-34	117.0	1510	1543
UBD/Beta-Prp	2.10e-80	270.1	1378	1683

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
           gH ++v+ + f ++  + ++++dDg+++vW+l++
   Q: 1510 GHRSKVNEVVFsPSeSHCATCGDDGSVRVWSLSS 1543
           8***********6669***************865 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls.............tgkc 86
           +t++++   ++ll  gs  g + vwd++   ++   + +++e+  + +s +   lv+gs+ r +++w +              +++ 
   Q: 1378 LTSLCY-GAEPLLYCGSNAGQVCVWDTSASRCFLAWEADDGEIGVLLCSGS--RLVSGSNTRRLRLWAVGavaelrrkgsgarSSSV 1461
           455555.66777888888888888888888888888888888888888887..5888888888888844444455577766655555 PP
   S: 87   vhtlk.ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkll 172
           ++  +   +  ++s  f++s d  v+G+   t+    + +g+  + + sgh++ vn vv++p+++ ++++++D+ vr+W+l++++l+
   Q: 1462 FMERElTLDGAIVSAVFHESMDMGVVGTTAGTLWYVSWAEGTSTR-LISGHRSKVNEVVFSPSESHCATCGDDGSVRVWSLSSMELV 1547
           555555677788888888888888888888888875666666666.89*************************************** PP
   S: 173  rtltgghtdsvyslsfdsng......kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrs 253
            +++   ++s  +l++++ +      +++++g  dgt++++++++ ++  +++ h +  + ++fs +++ ++sg +Dg + +   r+
   Q: 1548 IQFQV-LNQSCLCLAWSPPScgrpeqQHMAAGYSDGTLRVFNVSRISMELKMHPHLAALTAIAFSADGQTIISGDKDGLVAVSQPRT 1633
           ***98.*********88877888888************************************************************* PP
   S: 254  gdllktlqlhn....ssvisvav.......lsfgdnvlvlgse.dskvniwkl 294
           g + +tl+ h+    s    ++        +++++  l l+++ d++v iw+ 
   Q: 1634 GLTFRTLSDHRgapiS---TIQStskengaFGVEGTDLWLAASgDQRVSIWAS 1683
           ***********75541...3333233444566666666555555*******85 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

VPPVWQHPFL NVFRQFKVDE WKRSTKEGDV ATVMDKTLKC TVYRIRGTVS ASNYIQLPKT 60
STQSLGLTGR YLYLLFRPLS TKHFVIHLDL STEDRQVIRV SLSNLFKEFK STATWLQFPF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCGAG GTAGGCTCGC GGCCCGCAGA CCCGGGTGGG GGGCCGAGCG GTCCGGGGTC 60
CTGAGGCGGG GGGGGCGGGC AGGGTCCGGT GGCCGGTGCG CACTGAGCCT GCGGCCTGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR007714--CFA20/WDR90/C3orf67
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR030466--WDR90

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF05018--DUF667
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001801	Ailuropoda melanoleuca	72.91	0.00e+00	2520.00
IUUC-Apl-003387	Anas platyrhynchos	56.24	0.00e+00	986.00
IUUC-Aca-005235	Anolis carolinensis	54.12	0.00e+00	1657.00
IUUC-Ame-011595	Astyanax mexicanus	50.20	0.00e+00	1401.00
IUUC-Bta-012328	Bos taurus	72.60	0.00e+00	2418.00
IUUC-Cja-019058	Callithrix jacchus	66.82	0.00e+00	1169.00
IUUC-Cfa-020934	Canis familiaris	70.53	0.00e+00	2326.00
IUUC-Cpo-022025	Cavia porcellus	65.95	0.00e+00	2220.00
IUUC-Cre-022928	Chlamydomonas reinhardtii	28.40	2.00e-62	235.00
IUUC-Csa-023022	Chlorocebus sabaeus	68.08	0.00e+00	1304.00
IUUC-Cin-025133	Ciona intestinalis	37.95	0.00e+00	740.00
IUUC-Csv-025816	Ciona savignyi	35.19	0.00e+00	865.00
IUUC-Dre-028823	Danio rerio	46.82	0.00e+00	936.00
IUUC-Dno-029211	Dasypus novemcinctus	75.71	0.00e+00	958.00
IUUC-Dor-030211	Dipodomys ordii	66.40	0.00e+00	1932.00
IUUC-Ete-032363	Echinops telfairi	58.06	0.00e+00	908.00
IUUC-Eca-034296	Equus caballus	74.61	0.00e+00	2447.00
IUUC-Eeu-035226	Erinaceus europaeus	59.74	6.00e-167	581.00
IUUC-Fca-035384	Felis catus	72.98	0.00e+00	2479.00
IUUC-Fal-037660	Ficedula albicollis	55.21	0.00e+00	983.00
IUUC-Gga-040666	Gallus gallus	58.51	0.00e+00	1387.00
IUUC-Gac-041358	Gasterosteus aculeatus	47.50	0.00e+00	1552.00
IUUC-Ggo-045121	Gorilla gorilla	64.77	0.00e+00	2147.00
IUUC-Hsa-046289	Homo sapiens	64.94	0.00e+00	2097.00
IUUC-Itr-048485	Ictidomys tridecemlineatus	68.44	0.00e+00	2240.00
IUUC-Lch-050009	Latimeria chalumnae	50.35	0.00e+00	1700.00
IUUC-Loc-052629	Lepisosteus oculatus	47.57	0.00e+00	842.00
IUUC-Mcc-055834	Macaca mulatta	61.61	0.00e+00	1923.00
IUUC-Meu-056162	Macropus eugenii	59.36	0.00e+00	777.00
IUUC-Mga-060167	Meleagris gallopavo	54.98	0.00e+00	1677.00
IUUC-Mmr-060761	Microcebus murinus	77.05	2.00e-138	484.00
IUUC-Mdo-061886	Monodelphis domestica	58.73	0.00e+00	2133.00
IUUC-Mmu-063652	Mus musculus	68.07	0.00e+00	2384.00
IUUC-Nle-069133	Nomascus leucogenys	67.77	0.00e+00	1283.00
IUUC-Ont-072496	Oreochromis niloticus	47.77	0.00e+00	1698.00
IUUC-Oan-072833	Ornithorhynchus anatinus	50.34	0.00e+00	898.00
IUUC-Ola-086564	Oryzias latipes	45.96	0.00e+00	1582.00
IUUC-Oga-088919	Otolemur garnettii	64.78	0.00e+00	2189.00
IUUC-Oar-089946	Ovis aries	79.54	0.00e+00	1005.00
IUUC-Ptr-090755	Pan troglodytes	68.13	0.00e+00	1890.00
IUUC-Pan-092054	Papio anubis	67.70	0.00e+00	2236.00
IUUC-Psi-093467	Pelodiscus sinensis	58.58	0.00e+00	2041.00
IUUC-Pma-094573	Petromyzon marinus	43.57	0.00e+00	820.00
IUUC-Pfo-096849	Poecilia formosa	47.23	0.00e+00	1482.00
IUUC-Pab-098320	Pongo abelii	61.49	0.00e+00	1916.00
IUUC-Pca-100172	Procavia capensis	61.18	0.00e+00	1172.00
IUUC-Pva-102772	Pteropus vampyrus	76.20	0.00e+00	1476.00
IUUC-Rno-105046	Rattus norvegicus	68.82	0.00e+00	2416.00
IUUC-Sha-107094	Sarcophilus harrisii	59.55	0.00e+00	2194.00
IUUC-Ssc-116257	Sus scrofa	69.94	0.00e+00	2323.00
IUUC-Tgu-117323	Taeniopygia guttata	62.66	0.00e+00	889.00
IUUC-Tru-118717	Takifugu rubripes	46.07	0.00e+00	1540.00
IUUC-Tni-120108	Tetraodon nigroviridis	46.17	0.00e+00	1511.00
IUUC-Ttr-128378	Tursiops truncatus	83.74	0.00e+00	1069.00
IUUC-Xtr-131760	Xenopus tropicalis	51.68	0.00e+00	1755.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence