iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094553

UUCD1 version

UUC-PeM-00263

Ensembl Protein ID

ENSPMAP00000006438.1

UniProt Accession

S4RMK2; S4RMK2_PETMA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000005806.1	ENSPMAT00000006455.1	ENSPMAP00000006426.1
ENSPMAG00000005806.1	ENSPMAT00000006467.1	ENSPMAP00000006438.1
ENSPMAG00000005806.1	ENSPMAT00000006471.1	ENSPMAP00000006442.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-37	125.4	1520	1553
UBD/Beta-Prp	7.40e-85	283.9	1386	1697

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
           gH++ vt+laf +d  l++s++ Dg+++vWD r+
   Q: 1520 GHAEQVTGLAFsPDeALFASSAADGSLRVWDARS 1553
           8***********99999**************765 PP

UBD/Beta-Prp

   S: 12   vitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls.............tgk 85
            +tcv++   + ++++g  +g +  wd ++++++ + + ++ +   +++  +   lvt++  r ++ w++                +
   Q: 1386 EVTCVCY-GAGGVVFAGTSSGLVSAWDSERKSCFLTWEADSLALGVLECRGH--SLVTAGAGRRLRRWSVAsvdaarvqergtrGAD 1469
           5899***.66677777777*******************************99..6*************7777779999999998566 PP
   S: 86   cvhtlk..ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
           cv+     + ++s++s +f+ + d  v+G+++ t+    + + + ++ + sgh + v++++++pd+ l++s+++D+ +r+Wd ++ +
   Q: 1470 CVVLEAelRLDASAVSAAFDDDLDMGVVGTAVGTVWFIGWAECSSMR-LVSGHAEQVTGLAFSPDEALFASSAADGSLRVWDARSLE 1555
           6654334689************************9997778888887.99************************************* PP
   S: 171  llrtltgghtdsvyslsfdsng.......kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs.pnderlvsgssDgsiriW 249
           l  +++   ++  +++++++         + +++g  dg v+l++l++ e+v +++ h + v+ ++fs + +e+lvsg+ Dg + + 
   Q: 1556 LSVQFQV-LQQTCECVAWSRVParrsrfsRLVAAGYGDGAVRLFSLRSVEMVLKMRSHGSAVTALAFStDAGEFLVSGARDGLVVVS 1641
           *****87.8888999997776667778879999***********************************8899*************** PP
   S: 250  dlrsgdllktlqlhn.ssvisvavlsfgdnvl.........vlgsedskvniwklk 295
            l +g + ++++ h+ s ++++++++ +++ +         +++s ds+v iw+++
   Q: 1642 SLHTGATARVVTDHRpSPISAIDCVHSQERLVigshggemwLAASRDSRVSIWSCD 1697
           ***************8888999995555333333333443388888*******985 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

AVWQHPYVNV FKHCKVDEWK KASKEGEVTS AMDKTIKATV YKVVGHIPAA NYIQLPKTST 60
QSLGLTGRYL YLLFKPIPTK HFIVHLDVST EENQVVRISF SSLFREFKVT ATWLQFPFVC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTGTGTGC ATGCAGTATG GCAGCACCCG TATGTCAACG TGTTTAAGCA CTGCAAAGTG 60
GACGAATGGA AAAAAGCGTC AAAAGAAGGG GAGGTCACCT CCGCCATGGT AAATTGTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR007714--CFA20/WDR90/C3orf67
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR030466--WDR90

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF05018--DUF667
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001801	Ailuropoda melanoleuca	46.11	0.00e+00	847.00
IUUC-Cja-019058	Callithrix jacchus	47.02	0.00e+00	766.00
IUUC-Cfa-020934	Canis familiaris	42.96	0.00e+00	1287.00
IUUC-Cpo-022025	Cavia porcellus	43.62	0.00e+00	771.00
IUUC-Cre-022928	Chlamydomonas reinhardtii	28.34	8.00e-64	238.00
IUUC-Csa-023022	Chlorocebus sabaeus	44.80	0.00e+00	1403.00
IUUC-Dor-030211	Dipodomys ordii	45.11	0.00e+00	853.00
IUUC-Ete-032363	Echinops telfairi	42.44	1.00e-84	306.00
IUUC-Eeu-035226	Erinaceus europaeus	39.56	2.00e-143	501.00
IUUC-Fca-035384	Felis catus	46.31	0.00e+00	845.00
IUUC-Ggo-045121	Gorilla gorilla	44.24	0.00e+00	1112.00
IUUC-Mcc-055834	Macaca mulatta	38.30	0.00e+00	831.00
IUUC-Meu-056162	Macropus eugenii	42.92	3.00e-147	514.00
IUUC-Mga-060167	Meleagris gallopavo	44.90	0.00e+00	1298.00
IUUC-Mmr-060761	Microcebus murinus	51.29	4.00e-79	286.00
IUUC-Mmu-063652	Mus musculus	46.41	0.00e+00	1543.00
IUUC-Oan-072833	Ornithorhynchus anatinus	44.90	0.00e+00	795.00
IUUC-Ola-086564	Oryzias latipes	43.60	0.00e+00	1442.00
IUUC-Oga-088919	Otolemur garnettii	44.15	0.00e+00	1157.00
IUUC-Oar-089946	Ovis aries	49.62	3.00e-165	575.00
IUUC-Ptr-090755	Pan troglodytes	48.85	6.00e-173	600.00
IUUC-Pab-098320	Pongo abelii	43.11	0.00e+00	1195.00
IUUC-Pca-100172	Procavia capensis	45.31	0.00e+00	830.00
IUUC-Rno-105046	Rattus norvegicus	45.79	0.00e+00	1494.00
IUUC-Tgu-117323	Taeniopygia guttata	44.02	0.00e+00	1169.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence