iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011772

Ensembl Protein ID

ENSAMXP00000002636.1

UniProt Accession

W5K4X5; W5K4X5_ASTMX

Genbank Protein ID

ENSAMXP00000002636

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01000463

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000002577.1	ENSAMXT00000002636.1	ENSAMXP00000002636.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.10e-82	277.3	1571	1973

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle................kkkeklneenp............................. 42
           +GlkN g+tCYmNSv+Q+L++ip++r+ +l                 k         +                             
   Q: 1571 VGLKNAGATCYMNSVIQQLYMIPPIRNGILAiegtgsdvdddmsgdeK---------Qdnesnvdprdevfsyhhqfddkpslnkse 1648
           6******************************88888877666654331.........033333455677777777777777777776 PP
   S: 43   ..kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedksels 127
             ke +  +l++lq +f +l +s+ +++ pr ++k+++ + e ++  eq+Da Ef++ l+d+l+e+l                    
   Q: 1649 drKEYNIGVLRHLQVIFGHLASSRLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEAL-------------------- 1715
           6677777************************************************************.................... PP
   S: 128  deaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkk 214
                 k   ++ ++s++++g++ +q +c+ c ++++ ee+f++l++++++++     +l d++e+++k + leg+n+y+cekc+kk
   Q: 1716 ------KALGHPAMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQ-----NLLDSMEQYVKGDLLEGANAYHCEKCNKK 1791
           ......67999******************************************.....9**************************** PP
   S: 215  qeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts...............peekqke............ 274
           ++++k+l +kklP+vL ++LkRf ++ e+++ +k+n+++efp+eLd++p+++                +     +            
   Q: 1792 VDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAgvaklegsdmhpenqQ-----Viqqnepsepepp 1873
           *****************************************************7777777776655440.....1455566667777 PP
   S: 275  .kkkYeLiavvvHsGslssGHYvayvkn........ekgkWllfdDskVtevkeeevleetg......................... 327
            + +Y+L++v+vHsG++s+GHY++y+ +        e+++W++fdD  Vte+k+++ +e+++                         
   Q: 1874 cSSRYRLVGVLVHSGQASGGHYYSYIIQrngsggegERNRWYKFDDGDVTECKMDDDEEMKNqcfggeymgevfdhmmkrmsyrrqk 1960
           799*************************666665555555*******************9999************************ PP
   S: 328  ..staYvlfYkrr 338
             ++aY+lfY+r+
   Q: 1961 rwWNAYILFYERM 1973
           ***********96 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MTATTRGSPV GGNDSQDQGQ APDGQSQPPL PQNQTSSPTS SNENSPVSPP EEQGQGDCPP 60
QLEEEEPAFP HADLAKLDDM INRPRWVVPV LPKGELEVLL EAAIDLCKKG LDVKCEACQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCATGCGC AGTGGATCAG ACTCCGAGTT ATGGGAACTG GAGCAGGAGC TCACAGCCCG 60
AACCGAGCGG AGAGAGTTTG GGGGGGGCAG CAGCGCTGCT GGTGACGCAG GAAAAACACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001640	Ailuropoda melanoleuca	88.33	0.00e+00	4590.00
IUUC-Apl-003592	Anas platyrhynchos	89.79	0.00e+00	4645.00
IUUC-Aca-004939	Anolis carolinensis	89.90	0.00e+00	4627.00
IUUC-Bta-012775	Bos taurus	87.98	0.00e+00	4556.00
IUUC-Cja-019464	Callithrix jacchus	87.72	0.00e+00	4484.00
IUUC-Cfa-020569	Canis familiaris	89.89	0.00e+00	2986.00
IUUC-Csa-023405	Chlorocebus sabaeus	87.98	0.00e+00	4541.00
IUUC-Csv-025956	Ciona savignyi	53.63	0.00e+00	2500.00
IUUC-Dre-028329	Danio rerio	95.49	0.00e+00	4927.00
IUUC-Dno-028936	Dasypus novemcinctus	88.40	0.00e+00	4596.00
IUUC-Dor-030352	Dipodomys ordii	84.53	0.00e+00	2040.00
IUUC-Ete-032287	Echinops telfairi	87.07	0.00e+00	2528.00
IUUC-Eca-033352	Equus caballus	88.67	0.00e+00	4594.00
IUUC-Eeu-034907	Erinaceus europaeus	79.56	0.00e+00	1693.00
IUUC-Fca-035458	Felis catus	88.55	0.00e+00	4602.00
IUUC-Fal-036924	Ficedula albicollis	92.39	0.00e+00	4605.00
IUUC-Gmo-039578	Gadus morhua	92.67	0.00e+00	4657.00
IUUC-Gga-040978	Gallus gallus	90.05	0.00e+00	4653.00
IUUC-Gac-041970	Gasterosteus aculeatus	92.85	0.00e+00	4765.00
IUUC-Ggo-045575	Gorilla gorilla	88.44	0.00e+00	4558.00
IUUC-Hsa-046295	Homo sapiens	88.48	0.00e+00	4559.00
IUUC-Itr-048768	Ictidomys tridecemlineatus	88.32	0.00e+00	4594.00
IUUC-Lch-050493	Latimeria chalumnae	90.72	0.00e+00	4621.00
IUUC-Loc-052667	Lepisosteus oculatus	93.82	0.00e+00	4885.00
IUUC-Laf-054094	Loxodonta africana	88.78	0.00e+00	4581.00
IUUC-Mcc-054861	Macaca mulatta	87.18	0.00e+00	4531.00
IUUC-Meu-056849	Macropus eugenii	76.25	0.00e+00	1307.00
IUUC-Mga-060159	Meleagris gallopavo	89.97	0.00e+00	4649.00
IUUC-Mmr-060732	Microcebus murinus	88.36	0.00e+00	4597.00
IUUC-Mdo-062274	Monodelphis domestica	90.62	0.00e+00	4733.00
IUUC-Mmu-064056	Mus musculus	87.67	0.00e+00	4562.00
IUUC-Mpu-066669	Mustela putorius furo	88.36	0.00e+00	4595.00
IUUC-Mlu-067516	Myotis lucifugus	88.02	0.00e+00	4572.00
IUUC-Nle-069664	Nomascus leucogenys	89.65	0.00e+00	3386.00
IUUC-Opr-070185	Ochotona princeps	81.19	0.00e+00	741.00
IUUC-Ont-072119	Oreochromis niloticus	93.11	0.00e+00	4793.00
IUUC-Oan-073154	Ornithorhynchus anatinus	90.36	0.00e+00	4714.00
IUUC-Ocu-074485	Oryctolagus cuniculus	88.90	0.00e+00	4617.00
IUUC-Ola-086350	Oryzias latipes	91.97	0.00e+00	4690.00
IUUC-Oga-088328	Otolemur garnettii	88.63	0.00e+00	4640.00
IUUC-Oar-090098	Ovis aries	88.44	0.00e+00	4573.00
IUUC-Pan-091741	Papio anubis	89.45	0.00e+00	3507.00
IUUC-Psi-093040	Pelodiscus sinensis	90.02	0.00e+00	4647.00
IUUC-Pfo-096871	Poecilia formosa	92.27	0.00e+00	4766.00
IUUC-Pab-098374	Pongo abelii	88.02	0.00e+00	4540.00
IUUC-Pyt-104803	Pyrenophora triticirepentis	25.73	9.00e-48	186.00
IUUC-Rno-105377	Rattus norvegicus	87.79	0.00e+00	4569.00
IUUC-Sha-106648	Sarcophilus harrisii	88.14	0.00e+00	4557.00
IUUC-Sar-113729	Sorex araneus	88.83	0.00e+00	2851.00
IUUC-Ssc-116261	Sus scrofa	85.42	0.00e+00	4506.00
IUUC-Tgu-117126	Taeniopygia guttata	89.78	0.00e+00	4649.00
IUUC-Tru-117676	Takifugu rubripes	92.39	0.00e+00	4759.00
IUUC-Tni-120207	Tetraodon nigroviridis	93.22	0.00e+00	2115.00
IUUC-Ttr-128742	Tursiops truncatus	86.98	0.00e+00	4509.00
IUUC-Vpa-130581	Vicugna pacos	84.84	0.00e+00	4354.00
IUUC-Xtr-132145	Xenopus tropicalis	89.79	0.00e+00	4671.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence