iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091076

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03108045

Gene Name

USP43

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000008757.5	ENSPTRT00000050205.4	ENSPTRP00000052897.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.80e-92	309.5	101	710

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+gNtC+mN+v+QcLsn+  l+e+l     ++ + +      +e++++l+ l+++lw+++ +     e+++a++k+ ++f+g++q
   Q: 101  QGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYQAAPGR------AEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQ 183
           6****************************99666666655......79***************************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +Da Efl +lld+++e+l+ +++ p++e+   + +++s++  +++ +   ++s+++  Fq q++s+++c++c ++s++++pfl +slp+
   Q: 184  HDALEFLLWLLDRVHEDLEGSSRGPVSEKLPPEATKTSENclSPSAQLPLGQSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPI 272
           ******************999999999998888888888777889999999************************************** PP
   S: 177  pgkeetkke................................................................................ 185
           p ++++ ++                                                                                
   Q: 273  PLRQTRFLSvtlvfpsksqrflrvglavpilstvaalrkmvaeeggvpadevilvelypsgfqrsffdeedlntiaegdnvyafqvpps 361
           ****98888******************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 362  psqgtlsahplglsasprlaaregqrfslslhseskvlilfcnlvgsgqqasrfgppfliredravswaqlqqsilskvrhlmkseapv 450
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 451  qnlgslfsirvvglsvacsylspkdsrplchwavdrvlhlrrpggpphvklavewdssvkerlfgslqeeraqdadsvwqqqqahqqhs 539
           ***************************************************************************************** PP
   S: 186  .slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfctspeekq 272
            +l++c++ +tkee+l ++++++c++c+ +q+   kl+l++lP++Li+hLkRf   + +++r+k+++ v+fpl+ L+++p++++++++ 
   Q: 540  cTLDECFQFYTKEEQLAQDDAWKCPHCQVLQQGMVKLSLWTLPDILIIHLKRF--CQVGERRNKLSTLVKFPLSgLNMAPHVAQRSTSP 626
           *****************************************************..88899************************77777 PP
   S: 273  ke....................kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           +                     +  Y+L+av++H+G+l++GHY+ay++n  +g+W+ +dDs+V++++e+ev++   + aY+lfY++r
   Q: 627  EAglgpwpswkqpdclptsyplDFLYDLYAVCNHHGNLQGGHYTAYCRNsLDGQWYSYDDSTVEPLREDEVNT---RGAYILFYQKR 710
           66999999999999999**999***************************55788*******************...********985 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MDLGPGDAAG GGLLAPRPRR RRSLRRLFSR FLLALGSRSR PGDSPPRPQP GHCDGDGEGG 60
FACAPGPVPA APGSPGEERP PGPQPQLQLP AGDGARPPGA QGLKNHGNTC FMNAVVQCLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGCACCAGG AGCCTTAGAG AAGCTGTAGG GCCTGCTGGC CGCTCGTCCG CCTCGGGCCC 60
GGGGGCTCCG CGCCTGGAGC TGCGCCGGCG GCAGCCATGG ACCTGGGCCC CGGGGACGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	77.85	0.00e+00	1443.00
IUUC-Aca-004436	Anolis carolinensis	54.31	0.00e+00	806.00
IUUC-Ame-011153	Astyanax mexicanus	50.54	0.00e+00	885.00
IUUC-Bta-013560	Bos taurus	80.04	0.00e+00	1582.00
IUUC-Cja-018737	Callithrix jacchus	92.88	0.00e+00	1875.00
IUUC-Cfa-020347	Canis familiaris	77.04	0.00e+00	1467.00
IUUC-Csa-023656	Chlorocebus sabaeus	98.06	0.00e+00	1947.00
IUUC-Cho-024864	Choloepus hoffmanni	72.01	0.00e+00	913.00
IUUC-Dre-028066	Danio rerio	50.18	0.00e+00	913.00
IUUC-Dno-028855	Dasypus novemcinctus	72.92	0.00e+00	1366.00
IUUC-Dor-030475	Dipodomys ordii	88.30	0.00e+00	723.00
IUUC-Dme-032088	Drosophila melanogaster	36.65	1.00e-110	394.00
IUUC-Eca-034147	Equus caballus	85.61	0.00e+00	1474.00
IUUC-Eeu-034703	Erinaceus europaeus	62.02	0.00e+00	752.00
IUUC-Fca-036550	Felis catus	74.81	0.00e+00	1259.00
IUUC-Gac-042087	Gasterosteus aculeatus	51.84	0.00e+00	899.00
IUUC-Ggo-045171	Gorilla gorilla	99.42	0.00e+00	1973.00
IUUC-Hsa-045961	Homo sapiens	99.63	0.00e+00	1985.00
IUUC-Itr-048673	Ictidomys tridecemlineatus	75.14	0.00e+00	683.00
IUUC-Loc-052852	Lepisosteus oculatus	62.94	0.00e+00	929.00
IUUC-Laf-054033	Loxodonta africana	78.75	0.00e+00	1555.00
IUUC-Mcc-055431	Macaca mulatta	97.38	0.00e+00	1953.00
IUUC-Mmr-061035	Microcebus murinus	86.99	0.00e+00	1681.00
IUUC-Mdo-062172	Monodelphis domestica	66.96	0.00e+00	974.00
IUUC-Mmu-063966	Mus musculus	80.13	0.00e+00	1568.00
IUUC-Mpu-066307	Mustela putorius furo	78.65	0.00e+00	1422.00
IUUC-Nle-070172	Nomascus leucogenys	98.23	0.00e+00	1964.00
IUUC-Opr-070499	Ochotona princeps	74.52	0.00e+00	1401.00
IUUC-Ont-071920	Oreochromis niloticus	52.56	0.00e+00	946.00
IUUC-Ocu-074014	Oryctolagus cuniculus	83.82	0.00e+00	1217.00
IUUC-Ola-086360	Oryzias latipes	52.85	0.00e+00	945.00
IUUC-Oga-088202	Otolemur garnettii	84.01	0.00e+00	1692.00
IUUC-Oar-089819	Ovis aries	77.89	0.00e+00	1486.00
IUUC-Pan-092248	Papio anubis	97.67	0.00e+00	1935.00
IUUC-Pfo-096534	Poecilia formosa	60.27	0.00e+00	822.00
IUUC-Pab-098453	Pongo abelii	96.55	0.00e+00	1898.00
IUUC-Pca-100290	Procavia capensis	63.39	0.00e+00	724.00
IUUC-Pva-102317	Pteropus vampyrus	74.10	0.00e+00	1404.00
IUUC-Rno-104948	Rattus norvegicus	77.44	0.00e+00	1408.00
IUUC-Sha-106558	Sarcophilus harrisii	57.30	0.00e+00	1142.00
IUUC-Sar-113105	Sorex araneus	64.41	0.00e+00	1070.00
IUUC-Ssc-115312	Sus scrofa	80.37	0.00e+00	1565.00
IUUC-Tru-117995	Takifugu rubripes	62.83	0.00e+00	906.00
IUUC-Tsy-119325	Tarsius syrichta	77.98	0.00e+00	771.00
IUUC-Tni-120517	Tetraodon nigroviridis	58.43	0.00e+00	860.00
IUUC-Tbe-127439	Tupaia belangeri	71.90	3.00e-144	505.00
IUUC-Ttr-128829	Tursiops truncatus	72.96	0.00e+00	1394.00
IUUC-Vpa-130306	Vicugna pacos	81.61	0.00e+00	632.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence