iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041894

UUCD1 version

UUC-GaA-00724

Ensembl Protein ID

ENSGACP00000018652.1

UniProt Accession

G3PM21; G3PM21_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000014110.1	ENSGACT00000018690.1	ENSGACP00000018652.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.50e-115	385.8	571	901

Active Site

Position(s)	Description	Evidence
872	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           +++lk+ + v+f gEeg+++ Gv re+++ ls+e+ npd+ lf++s+ d +t+qpn++s + np+hl++F+f+G +lg+al++++l+++
   Q: 571  NEKLKQGIAVRFHGEEGMGQ-GVVREWFDILSNEIINPDYALFTQSA-DGTTFQPNSNSSV-NPDHLNYFQFAGHILGLALYHRQLVNI 656
           678999**************.**********************6666.67788*******9.89************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
            +++sfyk++lg +++++d++++dpe++k+l++i++n   di++lgl+ltfsv+++++g ++e+ LkpgG +i Vt++Nk eYv+lv+e
   Q: 657  YFTRSFYKHILGIPVNYQDVSSIDPEYAKNLQWILDN---DISDLGLELTFSVETDVFGAMEEVPLKPGGTSILVTQDNKAEYVQLVTE 742
           ***********************************99...************************************************* PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +r+++ i+ q++ f +Gf++ i ++l++lF+e elell++G++eidv+d+ ++t+y++gy +++ +iqwFwev++++s+eer  +LqFv
   Q: 743  LRMTRAIQPQINGFLQGFHTFILPSLIQLFDEYELELLLSGMPEIDVQDWCRNTEYTSGYDPQEAVIQWFWEVVKSLSQEERVLLLQFV 831
           ***************************************************************************************** PP
   S: 269  TgssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kg 332
           Tgssr+P+gGfa+l+     ++f++     + + lP+s+TC+n+LkLPeY+s+e+l+++Ll+A + +  g
   Q: 832  TGSSRVPHGGFAYLMggsgLQKFTVAAvPYTSNLLPTSSTCINMLKLPEYPSQEVLRDRLLVALHCGsYG 901
           *******************78888888577779*******************************986555 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MERAMEQLNV QLSRLTRSLR RARTVELPED NETAVYTLMP MVMADQHRSV SELLLNSKFD 60
VNYAFGRVKR SLLHIAANCG SVECLLLLLK RGANPNYQDI SGCTPLHLAA RNGQKKCMGK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAACGAG CGATGGAACA GCTCAACGTA CAGCTCAGCC GGCTAACCCG CTCCCTCCGC 60
CGGGCCAGGA CCGTGGAACT GCCAGAAGGT AACCGCATAG AACCCTTCCG CGGCCACATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR000569--HECT_dom

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50237--HECT

Pfam

PF12796--Ank_2
PF00632--HECT

PRINTS

PR01415--ANKYRIN

SMART

SM00248--ANK
SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001490	Ailuropoda melanoleuca	85.06	0.00e+00	1606.00
IUUC-Apl-003400	Anas platyrhynchos	78.09	0.00e+00	1030.00
IUUC-Aca-005375	Anolis carolinensis	84.27	0.00e+00	1606.00
IUUC-Ame-011847	Astyanax mexicanus	89.08	0.00e+00	1695.00
IUUC-Bta-012831	Bos taurus	85.20	0.00e+00	1571.00
IUUC-Cja-019160	Callithrix jacchus	85.27	0.00e+00	1610.00
IUUC-Cfa-020346	Canis familiaris	85.23	0.00e+00	1614.00
IUUC-Cpo-021766	Cavia porcellus	84.82	0.00e+00	1601.00
IUUC-Csa-023768	Chlorocebus sabaeus	85.03	0.00e+00	1610.00
IUUC-Cho-024688	Choloepus hoffmanni	79.17	0.00e+00	982.00
IUUC-Cin-025417	Ciona intestinalis	50.32	4.00e-138	485.00
IUUC-Csv-025993	Ciona savignyi	43.47	0.00e+00	758.00
IUUC-Dre-027819	Danio rerio	90.51	0.00e+00	1692.00
IUUC-Dno-029027	Dasypus novemcinctus	84.59	0.00e+00	1594.00
IUUC-Dor-030327	Dipodomys ordii	78.34	0.00e+00	1404.00
IUUC-Ete-032966	Echinops telfairi	78.96	0.00e+00	1479.00
IUUC-Eca-034339	Equus caballus	85.02	0.00e+00	1608.00
IUUC-Eeu-034544	Erinaceus europaeus	73.82	6.00e-135	474.00
IUUC-Fca-035617	Felis catus	82.32	0.00e+00	1104.00
IUUC-Fal-036687	Ficedula albicollis	82.60	0.00e+00	1610.00
IUUC-Gmo-039508	Gadus morhua	82.46	0.00e+00	1211.00
IUUC-Gga-040845	Gallus gallus	82.34	0.00e+00	1615.00
IUUC-Ggo-044465	Gorilla gorilla	81.84	0.00e+00	1539.00
IUUC-Hsa-045731	Homo sapiens	85.14	0.00e+00	1612.00
IUUC-Itr-048716	Ictidomys tridecemlineatus	85.53	0.00e+00	1613.00
IUUC-Lch-050436	Latimeria chalumnae	86.78	0.00e+00	1640.00
IUUC-Loc-052287	Lepisosteus oculatus	86.99	0.00e+00	1696.00
IUUC-Laf-053846	Loxodonta africana	85.25	0.00e+00	1615.00
IUUC-Mcc-055845	Macaca mulatta	85.14	0.00e+00	1612.00
IUUC-Meu-056060	Macropus eugenii	89.18	0.00e+00	630.00
IUUC-Mga-059935	Meleagris gallopavo	84.50	0.00e+00	1604.00
IUUC-Mmr-060960	Microcebus murinus	85.47	0.00e+00	1616.00
IUUC-Mdo-061851	Monodelphis domestica	82.41	0.00e+00	1597.00
IUUC-Mmu-063657	Mus musculus	84.18	0.00e+00	1605.00
IUUC-Mpu-066161	Mustela putorius furo	89.95	0.00e+00	759.00
IUUC-Mlu-067354	Myotis lucifugus	84.03	0.00e+00	1536.00
IUUC-Nle-069112	Nomascus leucogenys	85.25	0.00e+00	1614.00
IUUC-Opr-070686	Ochotona princeps	80.87	0.00e+00	746.00
IUUC-Ont-072398	Oreochromis niloticus	92.93	0.00e+00	1701.00
IUUC-Oan-073194	Ornithorhynchus anatinus	84.94	0.00e+00	1554.00
IUUC-Ocu-074397	Oryctolagus cuniculus	77.13	0.00e+00	1419.00
IUUC-Ola-086777	Oryzias latipes	85.61	0.00e+00	1633.00
IUUC-Oga-088684	Otolemur garnettii	85.14	0.00e+00	1611.00
IUUC-Oar-089428	Ovis aries	84.25	0.00e+00	1578.00
IUUC-Ptr-090529	Pan troglodytes	85.03	0.00e+00	1610.00
IUUC-Pan-091702	Papio anubis	85.25	0.00e+00	1615.00
IUUC-Psi-093969	Pelodiscus sinensis	81.88	0.00e+00	1541.00
IUUC-Pfo-097364	Poecilia formosa	93.37	0.00e+00	1704.00
IUUC-Pab-098574	Pongo abelii	85.14	0.00e+00	1612.00
IUUC-Pca-100525	Procavia capensis	78.02	3.00e-158	552.00
IUUC-Pva-102365	Pteropus vampyrus	74.59	0.00e+00	1357.00
IUUC-Rno-105153	Rattus norvegicus	84.60	0.00e+00	1603.00
IUUC-Sha-107319	Sarcophilus harrisii	82.48	0.00e+00	1601.00
IUUC-Stu-112894	Solanum tuberosum	35.04	1.00e-54	207.00
IUUC-Sar-113449	Sorex araneus	64.93	7.00e-135	474.00
IUUC-Ssc-115865	Sus scrofa	84.91	0.00e+00	1608.00
IUUC-Tgu-117225	Taeniopygia guttata	82.29	0.00e+00	1609.00
IUUC-Tru-118026	Takifugu rubripes	89.87	0.00e+00	1666.00
IUUC-Tsy-119407	Tarsius syrichta	72.86	0.00e+00	1322.00
IUUC-Tni-120234	Tetraodon nigroviridis	91.36	0.00e+00	1337.00
IUUC-Tbe-127708	Tupaia belangeri	72.12	0.00e+00	703.00
IUUC-Ttr-128667	Tursiops truncatus	84.69	0.00e+00	1607.00
IUUC-Vpa-130200	Vicugna pacos	84.74	0.00e+00	1555.00
IUUC-Xtr-132176	Xenopus tropicalis	83.37	0.00e+00	1617.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence