iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045432

UUCD1 version

UUC-GoG-00688

Ensembl Protein ID

ENSGGOP00000017278.1

UniProt Accession

G3RNB2; G3RNB2_GORGO

Protein Name

Uncharacterized protein

Gene Name

TEP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000000206.2	ENSGGOT00000027814.1	ENSGGOP00000017278.1
ENSGGOG00000000206.2	ENSGGOT00000000211.2	ENSGGOP00000000206.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-54	179.1	2018	2050
UBD/Beta-Prp	2.60e-79	266.9	1925	2101

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlrtg 33
           H d+vt++a+  d+ll+s+s Dg++ +WD+ +g
   Q: 2018 HRDWVTGCAWtKDNLLISCSSDGSVGLWDPESG 2050
           9*********877****************8877 PP

UBD/Beta-Prp

   S: 53   aevtavkfspdgkilvtgseDrtikvw.........dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcle 130
           ++v  +  s++  +l+++seD t+++w           ++++c   l+ghe  v ++sfs +g +l++G++dr + +wd++t +   
   Q: 1925 KPVLGLATSQE--LLASASEDFTVQLWprqlltrphKAEDFPCGTELRGHEGPVSCCSFSTDGGSLATGGRDRSLLCWDVRTPKTPV 2009
           55666666666..9*************666655555555******************************************988654 PP
   S: 131  e...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec 214
               + + h+++v++ ++ + +nll+s+s D+ v lWd ++g+ l ++ g h+++v  ++  +  +++vs+s+dgt+k+wd q  e 
   Q: 2010 LihsFPACHRDWVTGCAWTK-DNLLISCSSDGSVGLWDPESGQRLGQFLG-HQSAVSAVAAVE--EHVVSVSRDGTLKVWDHQGVE- 2091
           4456999*********9999.99**************************9.******999888..69**************98544. PP
   S: 215  vrtlnghtdn 224
           + +  +h+ +
   Q: 2092 LTSIPAHSGP 2101
           5566666555 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MEKLHGHVSA HPDILSLENR CLATLPSLKS TVSASPLFQS LQISHMTQAD LYRVNNSNCL 60
LSEPPSWRAQ HFSKGLDLST CPIALKSISA TETAQEATLG RWFDSEEKKG AETQMPSYSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAAAAC TCCATGGGCA TGTGTCTGCC CATCCAGACA TCCTCTCCTT GGAGAACCGG 60
TGCCTGGCCA CCCTCCCTAG TCTAAAGAGC ACTGTGTCTG CCAGCCCCTT GTTCCAGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR025139--DUF4062
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase
IPR002469--Peptidase_S9B_N
IPR008850--TEP1_N
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS51226--TEP1_N
PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05386--TEP1_N
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005697--C:telomerase holoenzyme complex
GO:0003720--F:telomerase activity
GO:0070034--F:telomerase RNA binding
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	76.42	0.00e+00	3623.00
IUUC-Aca-005102	Anolis carolinensis	41.20	0.00e+00	1549.00
IUUC-Ame-011165	Astyanax mexicanus	30.93	0.00e+00	714.00
IUUC-Bta-012323	Bos taurus	77.29	0.00e+00	3682.00
IUUC-Cja-019005	Callithrix jacchus	90.18	0.00e+00	4519.00
IUUC-Cfa-020803	Canis familiaris	70.24	0.00e+00	3242.00
IUUC-Cpo-022312	Cavia porcellus	72.78	0.00e+00	3412.00
IUUC-Csa-023287	Chlorocebus sabaeus	92.37	0.00e+00	4532.00
IUUC-Dre-028825	Danio rerio	33.94	0.00e+00	1076.00
IUUC-Dno-029455	Dasypus novemcinctus	76.92	0.00e+00	3606.00
IUUC-Dor-030328	Dipodomys ordii	74.26	0.00e+00	2624.00
IUUC-Ete-032385	Echinops telfairi	69.65	0.00e+00	1772.00
IUUC-Eca-033726	Equus caballus	80.83	0.00e+00	3928.00
IUUC-Eeu-034665	Erinaceus europaeus	75.33	0.00e+00	778.00
IUUC-Fca-035365	Felis catus	77.73	0.00e+00	3709.00
IUUC-Gmo-039584	Gadus morhua	31.44	2.00e-119	424.00
IUUC-Gac-042307	Gasterosteus aculeatus	34.41	0.00e+00	935.00
IUUC-Hsa-046182	Homo sapiens	96.02	0.00e+00	4717.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	78.88	0.00e+00	3810.00
IUUC-Lch-050186	Latimeria chalumnae	38.29	8.00e-79	287.00
IUUC-Laf-054524	Loxodonta africana	76.67	0.00e+00	3763.00
IUUC-Mcc-055628	Macaca mulatta	92.99	0.00e+00	4554.00
IUUC-Meu-056338	Macropus eugenii	59.09	0.00e+00	1182.00
IUUC-Mmr-060854	Microcebus murinus	81.65	0.00e+00	3963.00
IUUC-Mdo-062247	Monodelphis domestica	60.27	0.00e+00	2699.00
IUUC-Mmu-064406	Mus musculus	72.85	0.00e+00	3470.00
IUUC-Mpu-065806	Mustela putorius furo	75.82	0.00e+00	3644.00
IUUC-Mlu-068116	Myotis lucifugus	79.08	0.00e+00	3715.00
IUUC-Nle-069628	Nomascus leucogenys	93.43	0.00e+00	4091.00
IUUC-Opr-070242	Ochotona princeps	79.69	0.00e+00	2903.00
IUUC-Oan-073598	Ornithorhynchus anatinus	50.64	0.00e+00	1828.00
IUUC-Ocu-073933	Oryctolagus cuniculus	78.18	0.00e+00	3766.00
IUUC-Ola-086886	Oryzias latipes	34.26	0.00e+00	986.00
IUUC-Oga-088609	Otolemur garnettii	78.92	0.00e+00	3770.00
IUUC-Oar-089957	Ovis aries	76.95	0.00e+00	3582.00
IUUC-Ptr-090577	Pan troglodytes	94.13	0.00e+00	4620.00
IUUC-Pan-092397	Papio anubis	92.25	0.00e+00	4512.00
IUUC-Pma-094373	Petromyzon marinus	35.16	7.00e-77	281.00
IUUC-Pfo-096497	Poecilia formosa	34.39	0.00e+00	999.00
IUUC-Pab-098028	Pongo abelii	94.05	0.00e+00	4576.00
IUUC-Pca-101002	Procavia capensis	83.94	0.00e+00	1923.00
IUUC-Pva-102144	Pteropus vampyrus	68.78	0.00e+00	1451.00
IUUC-Rno-105828	Rattus norvegicus	72.44	0.00e+00	3511.00
IUUC-Sha-106469	Sarcophilus harrisii	60.10	0.00e+00	2787.00
IUUC-Sar-113035	Sorex araneus	77.48	0.00e+00	1469.00
IUUC-Ssc-116122	Sus scrofa	82.81	0.00e+00	3019.00
IUUC-Tru-118412	Takifugu rubripes	31.75	0.00e+00	1066.00
IUUC-Tsy-119257	Tarsius syrichta	77.43	0.00e+00	1643.00
IUUC-Tni-120032	Tetraodon nigroviridis	33.33	6.00e-39	154.00
IUUC-Tbe-127312	Tupaia belangeri	61.03	0.00e+00	848.00
IUUC-Ttr-128335	Tursiops truncatus	77.97	0.00e+00	3332.00
IUUC-Xtr-132524	Xenopus tropicalis	38.31	0.00e+00	1312.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence