iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052756

Ensembl Protein ID

ENSLOCP00000001982.1

UniProt Accession

W5M0S5; W5M0S5_LEPOC

Genbank Protein ID

ENSLOCP00000001982

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01034569

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000001685.1	ENSLOCT00000001987.1	ENSLOCP00000001982.1
ENSLOCG00000001685.1	ENSLOCT00000002014.1	ENSLOCP00000002009.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.20e-75	252.4	89	414
ULD/UDP/UBQ/UBQ_Other	1.10e-09	38.2	986	1046

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle..kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgy 87
           +Gl+Nlg+tCY+N  LQ+ ++  elr+ l    + + + ++ +++ + ++++++lq lf+ l++s++++++p+ l+kal+     +++ 
   Q: 89   VGLTNLGATCYVNTFLQVWFHNLELRQTLYLcqNPRAEEHDLDSDYEPQTICEHLQYLFALLQNSNRRYIDPSGLVKALG-----LDTG 172
           6**************************9998653444444455578899******************************9.....7889 PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDaqEf + +l+ le++l                       +++k+   +++i++ F gq+   ++c++c+++s+  + f++l+l++
   Q: 173  QQQDAQEFSKLFLSLLEDTL-----------------------SKQKNPNLQNVIQQQFCGQFAYVTVCNHCGRESQLLSRFYELELNI 238
           9*******************.......................456778889************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           +g++     +l+dc  +f kee+leg+n+y+ce+c++kq+a++++kl++lP++L l+L+Rf f++++++++k+n+ ++fp++Ld+ pf+
   Q: 239  QGHK-----QLTDCVTEFLKEEKLEGDNRYFCESCQSKQNATRRIKLQSLPRTLNLQLMRFVFDRQTGHKKKLNTFISFPETLDMGPFL 322
           ****.....9******************************************************************************* PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetg.......................st 329
           ++++    +k+ YeL+av++H G s+ sGHY+a+v++++ + W++f+D+++++++ ++ +   +                       ++
   Q: 323  ERND----VKCVYELTAVLIHRGvSAYSGHYIAHVRDTRTNdWYKFNDEEIEKMEGKKLQLGIEediaetsksqtrkpkcskgfhcsRN 407
           *944....389**************************87777************99999986558999********************* PP
   S: 330  aYvlfYk 336
           aY+l+Yk
   Q: 408  AYMLVYK 414
           ******8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 15   lkvnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           l v+ s t +eLK +i +++++ p +q+L ++G+ L +d  tL+++g+ ++++i+l  +++
   Q: 986  LIVSASQTLKELKIQIMHAFSVAPFDQNLSVDGRSLtDDSATLGSLGVIPECVICLKADEP 1046
           4489999*************************************************88875 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MAPRLQLERA AWRWIEAVKP EEVSAEHIET AYRIRLPACK RGSCRRNCKA NPNCLVGIGE 60
HLWLGEIDEN SFHNIDDPNS ERRDKNTFVG LTNLGATCYV NTFLQVWFHN LELRQTLYLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCCGC GGCTGCAGCT GGAAAGGGCA GCCTGGCGCT GGATCGAGGC GGTGAAACCC 60
GAGGAGGTGA GCGCGGAGCA CATCGAGACG GCGTACCGCA TCAGGCTGCC GGCGTGCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	33.55	2.00e-78	287.00
IUUC-Aml-001357	Ailuropoda melanoleuca	70.46	0.00e+00	1508.00
IUUC-Atr-002976	Amborella trichopoda	33.05	1.00e-77	285.00
IUUC-Apl-003773	Anas platyrhynchos	69.51	0.00e+00	1359.00
IUUC-Aca-004466	Anolis carolinensis	72.33	0.00e+00	783.00
IUUC-Aly-006249	Arabidopsis lyrata	29.94	3.00e-69	257.00
IUUC-Ath-006700	Arabidopsis thaliana	31.80	2.00e-80	294.00
IUUC-Ame-011554	Astyanax mexicanus	76.18	0.00e+00	1657.00
IUUC-Bta-012573	Bos taurus	70.46	0.00e+00	1523.00
IUUC-Bdi-014149	Brachypodium distachyon	33.06	9.00e-84	305.00
IUUC-Bol-016289	Brassica oleracea	32.54	5.00e-78	286.00
IUUC-Bra-017494	Brassica rapa	32.54	6.00e-80	292.00
IUUC-Cel-018662	Caenorhabditis elegans	30.09	1.00e-28	122.00
IUUC-Cja-019991	Callithrix jacchus	70.15	0.00e+00	1527.00
IUUC-Cfa-020294	Canis familiaris	70.90	0.00e+00	1542.00
IUUC-Cpo-021706	Cavia porcellus	69.47	0.00e+00	1449.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	36.69	1.00e-44	176.00
IUUC-Csa-023931	Chlorocebus sabaeus	70.99	0.00e+00	1536.00
IUUC-Cho-024566	Choloepus hoffmanni	63.43	1.00e-110	394.00
IUUC-Cin-025307	Ciona intestinalis	49.66	9.00e-82	296.00
IUUC-Csv-026006	Ciona savignyi	36.25	1.00e-153	537.00
IUUC-Cne-027065	Cryptococcus neoformans	28.36	2.00e-72	268.00
IUUC-Dre-027624	Danio rerio	77.86	0.00e+00	1726.00
IUUC-Dno-029633	Dasypus novemcinctus	72.58	0.00e+00	988.00
IUUC-Dor-030809	Dipodomys ordii	57.32	0.00e+00	892.00
IUUC-Ete-032818	Echinops telfairi	73.96	0.00e+00	761.00
IUUC-Eca-033692	Equus caballus	70.90	0.00e+00	1533.00
IUUC-Eeu-035185	Erinaceus europaeus	49.92	1.00e-154	540.00
IUUC-Fca-035676	Felis catus	70.59	0.00e+00	1535.00
IUUC-Fal-036913	Ficedula albicollis	70.95	0.00e+00	1526.00
IUUC-Gmo-038532	Gadus morhua	70.89	0.00e+00	1572.00
IUUC-Gga-041041	Gallus gallus	70.84	0.00e+00	1516.00
IUUC-Gac-042570	Gasterosteus aculeatus	74.05	0.00e+00	1627.00
IUUC-Gma-044136	Glycine max	29.14	3.00e-84	307.00
IUUC-Ggo-045367	Gorilla gorilla	67.66	0.00e+00	1437.00
IUUC-Hsa-046019	Homo sapiens	70.81	0.00e+00	1534.00
IUUC-Hvu-047303	Hordeum vulgare	34.50	5.00e-63	235.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	71.07	0.00e+00	1529.00
IUUC-Lch-049989	Latimeria chalumnae	73.33	0.00e+00	1608.00
IUUC-Lpe-051612	Leersia perrieri	33.28	4.00e-77	283.00
IUUC-Laf-054043	Loxodonta africana	70.99	0.00e+00	1534.00
IUUC-Mcc-054986	Macaca mulatta	69.99	0.00e+00	1523.00
IUUC-Meu-056228	Macropus eugenii	54.65	2.00e-176	613.00
IUUC-Mtr-058762	Medicago truncatula	29.92	7.00e-85	309.00
IUUC-Mga-059896	Meleagris gallopavo	69.95	0.00e+00	1425.00
IUUC-Mvi-060269	Microbotryum violaceum	38.19	2.00e-64	241.00
IUUC-Mmr-060887	Microcebus murinus	70.62	0.00e+00	1526.00
IUUC-Mdo-062506	Monodelphis domestica	70.71	0.00e+00	1532.00
IUUC-Mmu-063642	Mus musculus	70.46	0.00e+00	1524.00
IUUC-Mac-064896	Musa acuminata	31.36	1.00e-76	281.00
IUUC-Mpu-066194	Mustela putorius furo	70.81	0.00e+00	1521.00
IUUC-Mlu-067233	Myotis lucifugus	70.38	0.00e+00	1528.00
IUUC-Nle-069052	Nomascus leucogenys	69.91	0.00e+00	1524.00
IUUC-Opr-070890	Ochotona princeps	74.17	0.00e+00	947.00
IUUC-Ont-071450	Oreochromis niloticus	69.64	0.00e+00	1518.00
IUUC-Oan-073252	Ornithorhynchus anatinus	64.00	0.00e+00	773.00
IUUC-Ocu-073796	Oryctolagus cuniculus	70.44	0.00e+00	1301.00
IUUC-Oba-075563	Oryza barthii	34.35	1.00e-79	291.00
IUUC-Obr-076394	Oryza brachyantha	32.58	2.00e-79	291.00
IUUC-Ogl-077339	Oryza glaberrima	39.58	3.00e-41	162.00
IUUC-Ogu-079007	Oryza glumaepatula	34.27	3.00e-74	273.00
IUUC-Oin-079997	Oryza indica	34.35	6.00e-80	292.00
IUUC-Olo-080364	Oryza longistaminata	34.35	8.00e-80	292.00
IUUC-Ome-081165	Oryza meridionalis	34.33	4.00e-74	273.00
IUUC-Oni-083026	Oryza nivara	34.35	7.00e-80	292.00
IUUC-Opu-083284	Oryza punctata	34.22	3.00e-74	273.00
IUUC-Oru-084797	Oryza rufipogon	34.35	7.00e-80	292.00
IUUC-Osa-086221	Oryza sativa	39.58	3.00e-41	162.00
IUUC-Ola-086568	Oryzias latipes	74.28	0.00e+00	1629.00
IUUC-Oga-088687	Otolemur garnettii	69.96	0.00e+00	1519.00
IUUC-Oar-090345	Ovis aries	69.69	0.00e+00	1456.00
IUUC-Ptr-090734	Pan troglodytes	70.90	0.00e+00	1535.00
IUUC-Pan-091704	Papio anubis	68.18	0.00e+00	1462.00
IUUC-Psi-092937	Pelodiscus sinensis	68.58	0.00e+00	1283.00
IUUC-Ppa-095808	Physcomitrella patens	30.89	2.00e-68	254.00
IUUC-Pab-098129	Pongo abelii	70.90	0.00e+00	1536.00
IUUC-Pop-099494	Populus trichocarpa	32.24	5.00e-81	296.00
IUUC-Pca-100647	Procavia capensis	81.10	4.00e-162	565.00
IUUC-Ppe-102091	Prunus persica	32.04	3.00e-85	310.00
IUUC-Pva-102719	Pteropus vampyrus	70.62	0.00e+00	1523.00
IUUC-Rno-105363	Rattus norvegicus	70.16	0.00e+00	1531.00
IUUC-Sha-107620	Sarcophilus harrisii	68.21	0.00e+00	1424.00
IUUC-Smo-109487	Selaginella moellendorffii	26.78	1.00e-73	271.00
IUUC-Sit-110683	Setaria italica	33.23	7.00e-81	295.00
IUUC-Sly-111377	Solanum lycopersicum	31.50	1.00e-80	295.00
IUUC-Stu-111969	Solanum tuberosum	32.34	5.00e-69	255.00
IUUC-Sar-113099	Sorex araneus	70.24	0.00e+00	1301.00
IUUC-Sbi-113833	Sorghum bicolor	43.00	2.00e-58	219.00
IUUC-Ssc-115279	Sus scrofa	61.86	0.00e+00	943.00
IUUC-Tgu-117519	Taeniopygia guttata	67.86	0.00e+00	1367.00
IUUC-Tru-117651	Takifugu rubripes	71.53	0.00e+00	1580.00
IUUC-Tsy-119201	Tarsius syrichta	68.41	0.00e+00	1369.00
IUUC-Tni-120840	Tetraodon nigroviridis	73.11	0.00e+00	1609.00
IUUC-Tca-121674	Theobroma cacao	31.12	2.00e-87	317.00
IUUC-Tae-125814	Triticum aestivum	33.39	3.00e-79	290.00
IUUC-Tur-126599	Triticum urartu	33.71	9.00e-78	285.00
IUUC-Tbe-127782	Tupaia belangeri	66.92	0.00e+00	875.00
IUUC-Ttr-128312	Tursiops truncatus	69.69	0.00e+00	1500.00
IUUC-Vpa-130348	Vicugna pacos	70.41	0.00e+00	1450.00
IUUC-Vvi-131353	Vitis vinifera	31.94	9.00e-80	292.00
IUUC-Xtr-132172	Xenopus tropicalis	62.87	0.00e+00	1225.00
IUUC-Xma-133263	Xiphophorus maculatus	72.74	0.00e+00	1563.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence