iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067221

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02011606

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000006877.2	ENSMLUT00000006886.2	ENSMLUP00000006291.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-42	141.0	195	234
UBD/Beta-Prp	8.30e-53	179.5	190	396

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvllks 38
           Ht+  ++++f  sd   ++++s+Dgt+ +WD+ +g ll+s
   Q: 195  HTNYLSACSFtnSDmQQILTASGDGTCALWDVESGQLLQS 234
           999999*****988999******************99986 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgk.ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqclee 131
           +s+  h++  +a++f +++   ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+  +vwd+++gqc++ 
   Q: 190  KSVAMHTNYLSACSFTNSDMqQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKSMVWDMRSGQCVQ- 277
           5678899999999998876559**************************************9777************************. PP
   S: 132  tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
            ++ h++ vn+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g  v +l 
   Q: 278  AFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGARVSILF 366
           *******************************************95333556778999******************************** PP
   S: 220  ghtdnvksvrfspnderlvsgssDgsiriW 249
           gh++ v+ +r+sp+++ + sgs D ++r+W
   Q: 367  GHENRVSTLRVSPDGTAFCSGSWDHTLRVW 396
           ****************************** PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MCDQTFLVNV FGSCDKCFKQ RALRPVFKKS QQLSYCSTCA EIVSAGEGPR ESESISTSPL 60
PGPSLERRTG PERNSLFLVT MHQVAERVEA LGQFVMKTRR TLKGHGNKVL CMDWCKDKRR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGTGATC AGACCTTTCT AGTTAACGTA TTTGGCTCCT GTGACAAATG TTTTAAACAA 60
AGGGCTCTGA GACCAGTTTT CAAGAAATCT CAACAGCTCA GCTACTGCTC AACATGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	90.18	0.00e+00	738.00
IUUC-Apl-003399	Anas platyrhynchos	97.13	0.00e+00	639.00
IUUC-Aca-004861	Anolis carolinensis	86.15	0.00e+00	718.00
IUUC-Ame-011851	Astyanax mexicanus	86.61	0.00e+00	639.00
IUUC-Bta-012438	Bos taurus	90.65	0.00e+00	667.00
IUUC-Cel-018408	Caenorhabditis elegans	62.36	6.00e-132	463.00
IUUC-Cja-019086	Callithrix jacchus	91.65	0.00e+00	748.00
IUUC-Cfa-021255	Canis familiaris	90.63	0.00e+00	728.00
IUUC-Cpo-021398	Cavia porcellus	90.68	0.00e+00	748.00
IUUC-Csa-023776	Chlorocebus sabaeus	90.93	0.00e+00	668.00
IUUC-Cin-025305	Ciona intestinalis	56.06	3.00e-122	431.00
IUUC-Csv-026058	Ciona savignyi	61.06	6.00e-121	427.00
IUUC-Dre-028432	Danio rerio	78.84	0.00e+00	647.00
IUUC-Dno-029958	Dasypus novemcinctus	79.79	3.00e-134	471.00
IUUC-Dor-031013	Dipodomys ordii	98.05	5.00e-150	523.00
IUUC-Dme-031889	Drosophila melanogaster	64.45	2.00e-139	488.00
IUUC-Eca-033977	Equus caballus	89.67	0.00e+00	731.00
IUUC-Eeu-035079	Erinaceus europaeus	90.10	0.00e+00	730.00
IUUC-Fca-035693	Felis catus	89.72	0.00e+00	729.00
IUUC-Fal-037345	Ficedula albicollis	89.80	0.00e+00	663.00
IUUC-Gmo-039222	Gadus morhua	91.08	0.00e+00	629.00
IUUC-Gga-040320	Gallus gallus	90.08	0.00e+00	664.00
IUUC-Gac-042644	Gasterosteus aculeatus	85.27	0.00e+00	636.00
IUUC-Ggo-044489	Gorilla gorilla	89.70	0.00e+00	734.00
IUUC-Hsa-046434	Homo sapiens	91.69	0.00e+00	753.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	92.43	2.00e-173	600.00
IUUC-Loc-052790	Lepisosteus oculatus	84.01	0.00e+00	684.00
IUUC-Laf-054255	Loxodonta africana	89.87	0.00e+00	734.00
IUUC-Mcc-055610	Macaca mulatta	91.14	0.00e+00	744.00
IUUC-Meu-056819	Macropus eugenii	85.03	0.00e+00	678.00
IUUC-Mga-059740	Meleagris gallopavo	85.07	0.00e+00	704.00
IUUC-Mmr-061221	Microcebus murinus	91.69	0.00e+00	755.00
IUUC-Mdo-062619	Monodelphis domestica	91.22	0.00e+00	671.00
IUUC-Mmu-064266	Mus musculus	91.44	0.00e+00	751.00
IUUC-Mpu-065766	Mustela putorius furo	97.68	2.00e-178	617.00
IUUC-Nle-069515	Nomascus leucogenys	96.88	0.00e+00	649.00
IUUC-Opr-070195	Ochotona princeps	83.29	0.00e+00	663.00
IUUC-Ont-071535	Oreochromis niloticus	73.30	1.00e-163	568.00
IUUC-Oan-072899	Ornithorhynchus anatinus	97.30	8.00e-107	378.00
IUUC-Ocu-074666	Oryctolagus cuniculus	98.68	2.00e-179	620.00
IUUC-Ola-086578	Oryzias latipes	93.08	0.00e+00	629.00
IUUC-Oga-089090	Otolemur garnettii	90.48	0.00e+00	745.00
IUUC-Oar-090017	Ovis aries	88.89	0.00e+00	725.00
IUUC-Ptr-091280	Pan troglodytes	88.92	0.00e+00	718.00
IUUC-Pan-092198	Papio anubis	96.88	0.00e+00	649.00
IUUC-Psi-093030	Pelodiscus sinensis	84.44	0.00e+00	706.00
IUUC-Pma-094140	Petromyzon marinus	74.06	3.00e-90	323.00
IUUC-Pfo-097182	Poecilia formosa	91.69	0.00e+00	633.00
IUUC-Pab-098157	Pongo abelii	91.22	0.00e+00	665.00
IUUC-Pca-100988	Procavia capensis	70.03	7.00e-152	530.00
IUUC-Pva-102232	Pteropus vampyrus	98.13	2.00e-158	551.00
IUUC-Rno-105526	Rattus norvegicus	87.61	0.00e+00	629.00
IUUC-Sha-106754	Sarcophilus harrisii	89.42	0.00e+00	723.00
IUUC-Ssc-115390	Sus scrofa	91.18	0.00e+00	756.00
IUUC-Tgu-117377	Taeniopygia guttata	85.93	0.00e+00	687.00
IUUC-Tru-117938	Takifugu rubripes	92.79	0.00e+00	629.00
IUUC-Tsy-119392	Tarsius syrichta	79.85	2.00e-179	621.00
IUUC-Tni-119834	Tetraodon nigroviridis	67.51	1.00e-156	545.00
IUUC-Tbe-127469	Tupaia belangeri	87.57	0.00e+00	665.00
IUUC-Ttr-128252	Tursiops truncatus	87.41	0.00e+00	711.00
IUUC-Vpa-130173	Vicugna pacos	79.59	8.00e-154	536.00
IUUC-Xtr-131803	Xenopus tropicalis	84.63	0.00e+00	692.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence