iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gga-040896

Ensembl Protein ID

ENSGALP00000009301.5

UniProt Accession

Q5F3R7; DCA12_CHICK

Genbank Protein ID

CAH65217.1

Protein Name

DDB1- and CUL4-associated factor 12; WD repeat-containing protein 40A

Genbank Nucleotide ID

AJ851583

Gene Name

DCAF12; WDR40A; RCJMB04_8j18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000005800.5	ENSGALT00000009315.5	ENSGALP00000009301.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-23	81.5	154	191

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlrtgvllk 37
           gH+d+++++a+ sdt+ vsGs+Dg++ +W+++++vl k
   Q: 154  GHKDWIFSIAWiSDTMAVSGSRDGSMGLWEVTEDVLSK 191
           8********************************99876 PP

Organism

Gallus gallus

Functional Description
(View)

May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

Protein Sequence
(Fasta)

MARKTVSRKR KAAAASAAGP GGLYGEQYGW DHSVHKRKRL PPVKRSLVYY LKEREFHLGT 60
LNKVFASQWL NHRQVVCGTK CNTLFVVDVQ TGQITKIPIL KDREPGMVNQ QGCGIHAIEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAATGTCG TGAAGGGCGG TCCGGAGGGG CCTGCGGCGG AGAGAGCGGC CGGGCTCGGC 60
TGCCGGCACT TAATGCCCCG TGTCCTGGCG GCCGCCTGCT CCGTCTGCTC CATGTGGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0016567--P:protein ubiquitination

KEGG

gga:427396

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002102	Ailuropoda melanoleuca	84.65	0.00e+00	762.00
IUUC-Apl-003794	Anas platyrhynchos	91.94	0.00e+00	824.00
IUUC-Aca-004264	Anolis carolinensis	94.26	0.00e+00	789.00
IUUC-Ame-011254	Astyanax mexicanus	77.00	0.00e+00	627.00
IUUC-Bta-012923	Bos taurus	84.21	0.00e+00	760.00
IUUC-Cja-019590	Callithrix jacchus	92.15	0.00e+00	655.00
IUUC-Cfa-021123	Canis familiaris	84.65	0.00e+00	762.00
IUUC-Cpo-021733	Cavia porcellus	81.34	7.00e-158	549.00
IUUC-Csa-023339	Chlorocebus sabaeus	84.43	0.00e+00	763.00
IUUC-Cho-024837	Choloepus hoffmanni	71.01	5.00e-135	473.00
IUUC-Dre-027571	Danio rerio	77.81	0.00e+00	630.00
IUUC-Dno-029106	Dasypus novemcinctus	86.77	0.00e+00	763.00
IUUC-Dor-030162	Dipodomys ordii	58.29	2.00e-125	442.00
IUUC-Dme-031774	Drosophila melanogaster	43.09	6.00e-78	284.00
IUUC-Ete-033140	Echinops telfairi	59.72	9.00e-81	293.00
IUUC-Eca-034316	Equus caballus	84.65	0.00e+00	764.00
IUUC-Eeu-034641	Erinaceus europaeus	84.59	1.00e-171	595.00
IUUC-Fca-036150	Felis catus	86.28	0.00e+00	759.00
IUUC-Fal-036636	Ficedula albicollis	90.35	0.00e+00	823.00
IUUC-Gmo-038736	Gadus morhua	82.23	2.00e-178	618.00
IUUC-Gac-042623	Gasterosteus aculeatus	79.69	0.00e+00	637.00
IUUC-Ggo-044968	Gorilla gorilla	92.15	0.00e+00	657.00
IUUC-Hsa-046020	Homo sapiens	84.87	0.00e+00	766.00
IUUC-Itr-048766	Ictidomys tridecemlineatus	84.65	0.00e+00	766.00
IUUC-Lch-050244	Latimeria chalumnae	82.64	0.00e+00	724.00
IUUC-Loc-052777	Lepisosteus oculatus	75.12	0.00e+00	653.00
IUUC-Laf-054505	Loxodonta africana	83.11	0.00e+00	755.00
IUUC-Mcc-055187	Macaca mulatta	85.81	0.00e+00	755.00
IUUC-Meu-056026	Macropus eugenii	82.52	0.00e+00	716.00
IUUC-Mga-059618	Meleagris gallopavo	55.38	6.00e-121	427.00
IUUC-Mmr-061121	Microcebus murinus	78.00	0.00e+00	666.00
IUUC-Mdo-062823	Monodelphis domestica	87.12	0.00e+00	759.00
IUUC-Mmu-064332	Mus musculus	84.65	0.00e+00	765.00
IUUC-Mpu-066157	Mustela putorius furo	84.65	0.00e+00	762.00
IUUC-Mlu-067146	Myotis lucifugus	84.21	0.00e+00	766.00
IUUC-Nle-069179	Nomascus leucogenys	82.68	0.00e+00	736.00
IUUC-Opr-070970	Ochotona princeps	89.24	0.00e+00	635.00
IUUC-Ont-072013	Oreochromis niloticus	76.27	0.00e+00	630.00
IUUC-Oan-072810	Ornithorhynchus anatinus	87.83	2.00e-55	207.00
IUUC-Ocu-074646	Oryctolagus cuniculus	84.43	0.00e+00	764.00
IUUC-Ola-087062	Oryzias latipes	78.65	2.00e-180	624.00
IUUC-Olu-087756	Ostreococcus lucimarinus	26.95	7.00e-16	78.20
IUUC-Oga-089071	Otolemur garnettii	84.43	0.00e+00	762.00
IUUC-Oar-089522	Ovis aries	84.21	0.00e+00	758.00
IUUC-Ptr-091042	Pan troglodytes	80.04	0.00e+00	714.00
IUUC-Pan-092832	Papio anubis	84.43	0.00e+00	765.00
IUUC-Psi-093131	Pelodiscus sinensis	88.76	0.00e+00	798.00
IUUC-Pma-094151	Petromyzon marinus	74.24	7.00e-57	213.00
IUUC-Pfo-096970	Poecilia formosa	75.54	1.00e-179	622.00
IUUC-Pab-098019	Pongo abelii	84.87	0.00e+00	766.00
IUUC-Pca-100401	Procavia capensis	74.13	9.00e-142	496.00
IUUC-Pva-103128	Pteropus vampyrus	84.43	0.00e+00	765.00
IUUC-Rno-105945	Rattus norvegicus	72.81	2.00e-177	615.00
IUUC-Sha-107518	Sarcophilus harrisii	92.75	0.00e+00	659.00
IUUC-Smo-108742	Selaginella moellendorffii	34.20	1.00e-51	196.00
IUUC-Sar-113026	Sorex araneus	83.24	8.00e-175	606.00
IUUC-Ssc-115446	Sus scrofa	85.08	0.00e+00	732.00
IUUC-Tgu-117240	Taeniopygia guttata	84.86	0.00e+00	653.00
IUUC-Tru-118560	Takifugu rubripes	74.82	3.00e-180	624.00
IUUC-Tsy-119344	Tarsius syrichta	90.34	0.00e+00	721.00
IUUC-Tni-119714	Tetraodon nigroviridis	80.26	0.00e+00	632.00
IUUC-Tbe-127634	Tupaia belangeri	90.00	8.00e-86	310.00
IUUC-Ttr-128503	Tursiops truncatus	84.21	0.00e+00	759.00
IUUC-Vpa-130126	Vicugna pacos	81.60	2.00e-129	455.00
IUUC-Xtr-132744	Xenopus tropicalis	46.70	2.00e-89	322.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence