iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045441

UUCD1 version

UUC-GoG-00447

Ensembl Protein ID

ENSGGOP00000010858.2

UniProt Accession

G3R6B2; G3R6B2_GORGO

Protein Name

Uncharacterized protein

Gene Name

TTC3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000011116.2	ENSGGOT00000011179.2	ENSGGOP00000010858.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.50e-07	32.2	1958	1998

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC+e f  k+ ++vl CgH +h+ C+++w       +++  CP C+
   Q: 1958 CEICHEVFksKN-VRVLKCGHKYHKGCFKQW------LKGQSACPACQ 1998
           99****998566.******************......**********7 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MDNFAEGDFT VADYALLEDC PHVDDCVFAA EFMTNDYVRV TQLYCDGVGV QYKDYIQSER 60
NLGEYVGIFN VNLWKDYKGR SIHPVIAIQQ IYMLFKNARI LHSFISSLSI SIFAFLLLSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAATT TTGCTGAGGG AGATTTCACT GTGGCGGATT ATGCCTTGTT AGAAGATTGC 60
CCTCACGTGG ATGATTGTGT CTTTGCTGCT GAATTTATGA CCAATGATTA TGTTCGTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0802--TPR repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR011029--DEATH-like_dom
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50005--TPR
PS50293--TPR_REGION
PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING
SM00028--TPR

Gene Ontology

GO:0005829--C:cytosol
GO:0016021--C:integral component of membrane
GO:0005730--C:nucleolus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0070936--P:protein K48-linked ubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002231	Ailuropoda melanoleuca	96.23	1.00e-27	113.00
IUUC-Apl-003622	Anas platyrhynchos	48.81	0.00e+00	974.00
IUUC-Aca-004579	Anolis carolinensis	40.24	2.00e-28	120.00
IUUC-Ame-011167	Astyanax mexicanus	37.86	3.00e-165	576.00
IUUC-Bta-012916	Bos taurus	76.22	0.00e+00	2742.00
IUUC-Cja-019100	Callithrix jacchus	85.53	0.00e+00	3063.00
IUUC-Cfa-020974	Canis familiaris	78.77	0.00e+00	2952.00
IUUC-Cpo-022435	Cavia porcellus	62.55	0.00e+00	1707.00
IUUC-Csa-023245	Chlorocebus sabaeus	87.46	0.00e+00	3275.00
IUUC-Cho-024822	Choloepus hoffmanni	67.33	0.00e+00	1162.00
IUUC-Dre-027805	Danio rerio	35.61	6.00e-106	379.00
IUUC-Dno-029413	Dasypus novemcinctus	61.32	0.00e+00	2126.00
IUUC-Dor-030670	Dipodomys ordii	80.10	0.00e+00	1516.00
IUUC-Ete-032367	Echinops telfairi	40.26	1.00e-111	399.00
IUUC-Eca-033891	Equus caballus	78.47	0.00e+00	2918.00
IUUC-Fca-035889	Felis catus	77.11	0.00e+00	2829.00
IUUC-Fal-037399	Ficedula albicollis	42.64	0.00e+00	833.00
IUUC-Gga-040490	Gallus gallus	46.62	0.00e+00	911.00
IUUC-Hsa-045811	Homo sapiens	93.31	0.00e+00	3507.00
IUUC-Itr-048367	Ictidomys tridecemlineatus	82.43	0.00e+00	944.00
IUUC-Lch-049809	Latimeria chalumnae	40.96	1.00e-127	451.00
IUUC-Loc-052533	Lepisosteus oculatus	33.90	0.00e+00	679.00
IUUC-Laf-053785	Loxodonta africana	62.41	0.00e+00	1373.00
IUUC-Mcc-054801	Macaca mulatta	90.47	0.00e+00	3374.00
IUUC-Mga-059963	Meleagris gallopavo	47.32	0.00e+00	951.00
IUUC-Mmr-060707	Microcebus murinus	79.19	0.00e+00	2851.00
IUUC-Mdo-062718	Monodelphis domestica	48.97	0.00e+00	1234.00
IUUC-Mmu-064257	Mus musculus	72.36	0.00e+00	2569.00
IUUC-Mpu-066020	Mustela putorius furo	77.92	0.00e+00	2886.00
IUUC-Mlu-067023	Myotis lucifugus	73.28	0.00e+00	2659.00
IUUC-Nle-069965	Nomascus leucogenys	91.72	0.00e+00	3401.00
IUUC-Opr-070629	Ochotona princeps	62.77	0.00e+00	937.00
IUUC-Ont-072604	Oreochromis niloticus	35.01	5.00e-144	506.00
IUUC-Oan-072830	Ornithorhynchus anatinus	47.07	0.00e+00	1393.00
IUUC-Ocu-073774	Oryctolagus cuniculus	77.43	0.00e+00	2763.00
IUUC-Ola-086847	Oryzias latipes	35.27	1.00e-144	507.00
IUUC-Oga-088372	Otolemur garnettii	81.25	0.00e+00	2252.00
IUUC-Oar-090039	Ovis aries	74.78	0.00e+00	2720.00
IUUC-Ptr-091171	Pan troglodytes	93.46	0.00e+00	3502.00
IUUC-Pan-091926	Papio anubis	87.10	0.00e+00	3357.00
IUUC-Psi-093680	Pelodiscus sinensis	48.72	0.00e+00	960.00
IUUC-Pab-098120	Pongo abelii	92.37	0.00e+00	3473.00
IUUC-Pva-102424	Pteropus vampyrus	74.21	0.00e+00	1604.00
IUUC-Pte-104037	Pyrenophora teres	35.42	8.00e-07	47.80
IUUC-Pyt-104680	Pyrenophora triticirepentis	37.50	4.00e-07	48.90
IUUC-Rno-105101	Rattus norvegicus	71.78	0.00e+00	2580.00
IUUC-Sha-106607	Sarcophilus harrisii	62.23	0.00e+00	915.00
IUUC-Sar-113589	Sorex araneus	71.05	0.00e+00	2026.00
IUUC-Ssc-115530	Sus scrofa	81.59	0.00e+00	2345.00
IUUC-Tgu-116671	Taeniopygia guttata	42.74	0.00e+00	773.00
IUUC-Tru-118283	Takifugu rubripes	33.20	7.00e-134	471.00
IUUC-Tsy-118872	Tarsius syrichta	77.73	0.00e+00	2110.00
IUUC-Tbe-127996	Tupaia belangeri	76.21	0.00e+00	1797.00
IUUC-Ttr-128379	Tursiops truncatus	80.24	0.00e+00	2754.00
IUUC-Vpa-130372	Vicugna pacos	77.40	0.00e+00	2438.00
IUUC-Xtr-132649	Xenopus tropicalis	36.10	6.00e-178	619.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence