iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069247

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01135989

Gene Name

FBXW10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000010480.2	ENSNLET00000013368.2	ENSNLEP00000012742.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.00e-29	98.8	493	530
UBD/Beta-Prp	3.70e-42	144.5	417	686

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvllks 38
           gH++ +tc+++ + ++lvsG++D+++kvWD++tg++lk+
   Q: 493  GHQGTITCMDL-CkNRLVSGGRDCQVKVWDVDTGKCLKT 530
           8**********.4489********************986 PP

UBD/Beta-Prp

   S: 15   cvkfspdksllatgsrdgtikvwdvttgkll.rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
           ++++  +++l+a++s +++i + d+ + k++  ++ gh + v+a+ + +++++l++gs D  i+ wdl++g c++++ gh+ +++++++
   Q: 417  VIHY-SGGDLIAVSS-NQKIHLLDIIQVKAIpVEFRGHAGSVRALFLCEEENFLLSGSYDLSIRYWDLKSGACIRIFGGHQGTITCMDL 503
           5556.6778888887.9**********99962567****************************************************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsn 191
           ++  ++lvsG++d  ++vwd++tg+cl+ t+  h++ +  +++++   ++vs++  ++v++W ++t++l++tl g h+++v++l fd+ 
   Q: 504  CK--NRLVSGGRDCQVKVWDVDTGKCLK-TF-RHKDPILATRIND--TYIVSSCERGVVKVWHIATAQLVKTLNG-HEGAVKCLFFDQ- 584
           **..***********************9.55.5777888889988..***************************9.************. PP
   S: 192  gkelvsgsldgtvklwdlq..tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdn 278
             +l+sgs+dg v  w++    ++c+++++  ++   +  ++    r++s+ +Dg iri++  +g+++k+++  n +  +v  + +++n
   Q: 585  -WHLLSGSTDGLVMAWSMVgkYERCLMAFKHPKEVLHVSLLF---LRVISACADGKIRIYNFLNGNCMKVIKA-NGRGDPVLSFFIQGN 668
           .8****************988899999998777666555555...89************************99.545555555566888 PP
   S: 279  vlvlgsedskvniwklkkn 297
            +v  +e s+v +++++ +
   Q: 669  RMVVNTE-SNVLMFQFEHI 686
           8888777.68888887665 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MENLESRLKN APYFRCEKGT DSIPLCQKCE TCVLAWKIFS TKEWFCRIND ISQRRFLVGI 60
LKQLNSLYLL HYFQNILQTT QGKDFIYNRS RIDLSKKEGK VVKSSLNQML DKTVEQKMKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAAACC TGGAATCGAG ACTCAAGAAT GCCCCCTATT TTCGTTGTGA GAAGGGAACT 60
GATTCCATTC CTCTGTGCCA GAAGTGTGAG ACGTGTGTCT TAGCCTGGAA GATCTTCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

KEGG

nle:100593897

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001837	Ailuropoda melanoleuca	74.94	0.00e+00	684.00
IUUC-Apl-003572	Anas platyrhynchos	50.71	1.00e-131	464.00
IUUC-Aca-004297	Anolis carolinensis	44.88	2.00e-174	606.00
IUUC-Ame-011058	Astyanax mexicanus	38.80	1.00e-138	486.00
IUUC-Bta-012667	Bos taurus	75.83	0.00e+00	729.00
IUUC-Cja-019163	Callithrix jacchus	85.68	0.00e+00	1380.00
IUUC-Cfa-020784	Canis familiaris	76.84	0.00e+00	1196.00
IUUC-Cpo-021429	Cavia porcellus	74.78	0.00e+00	723.00
IUUC-Csa-023597	Chlorocebus sabaeus	93.72	0.00e+00	1319.00
IUUC-Cho-024559	Choloepus hoffmanni	62.43	0.00e+00	645.00
IUUC-Dre-027496	Danio rerio	44.96	4.00e-112	399.00
IUUC-Dno-028995	Dasypus novemcinctus	77.70	0.00e+00	1201.00
IUUC-Ete-032823	Echinops telfairi	76.22	5.00e-88	319.00
IUUC-Eca-033666	Equus caballus	75.04	0.00e+00	915.00
IUUC-Eeu-035054	Erinaceus europaeus	78.18	4.00e-64	239.00
IUUC-Fca-035589	Felis catus	72.93	0.00e+00	1137.00
IUUC-Fal-037403	Ficedula albicollis	45.69	3.00e-117	416.00
IUUC-Gmo-038669	Gadus morhua	32.76	3.00e-75	275.00
IUUC-Gga-041227	Gallus gallus	45.55	5.00e-129	455.00
IUUC-Ggo-044603	Gorilla gorilla	61.41	2.00e-119	422.00
IUUC-Hsa-046221	Homo sapiens	95.32	0.00e+00	1499.00
IUUC-Itr-049011	Ictidomys tridecemlineatus	76.02	0.00e+00	1169.00
IUUC-Lch-050046	Latimeria chalumnae	38.60	1.00e-156	547.00
IUUC-Loc-052366	Lepisosteus oculatus	42.80	4.00e-160	558.00
IUUC-Laf-053745	Loxodonta africana	74.91	0.00e+00	1189.00
IUUC-Mcc-054826	Macaca mulatta	93.11	0.00e+00	1445.00
IUUC-Meu-056636	Macropus eugenii	53.25	2.00e-39	157.00
IUUC-Mga-060185	Meleagris gallopavo	45.34	1.00e-127	450.00
IUUC-Mdo-062382	Monodelphis domestica	52.17	0.00e+00	701.00
IUUC-Mmu-063623	Mus musculus	70.76	0.00e+00	1080.00
IUUC-Mpu-066872	Mustela putorius furo	71.07	0.00e+00	875.00
IUUC-Mlu-067552	Myotis lucifugus	66.27	0.00e+00	644.00
IUUC-Opr-070455	Ochotona princeps	75.33	0.00e+00	736.00
IUUC-Ont-071926	Oreochromis niloticus	42.69	3.00e-97	349.00
IUUC-Oan-073411	Ornithorhynchus anatinus	49.36	0.00e+00	661.00
IUUC-Ocu-073893	Oryctolagus cuniculus	76.65	0.00e+00	950.00
IUUC-Oga-087937	Otolemur garnettii	77.85	0.00e+00	757.00
IUUC-Oar-089680	Ovis aries	70.83	0.00e+00	1131.00
IUUC-Ptr-091549	Pan troglodytes	88.82	0.00e+00	1368.00
IUUC-Pan-091904	Papio anubis	93.54	0.00e+00	1437.00
IUUC-Psi-093181	Pelodiscus sinensis	48.60	0.00e+00	699.00
IUUC-Pma-094711	Petromyzon marinus	43.05	1.00e-72	265.00
IUUC-Pab-098067	Pongo abelii	95.53	0.00e+00	1489.00
IUUC-Pca-100867	Procavia capensis	77.55	1.00e-130	459.00
IUUC-Pva-102209	Pteropus vampyrus	77.54	0.00e+00	1121.00
IUUC-Rno-105374	Rattus norvegicus	65.11	0.00e+00	975.00
IUUC-Sha-107459	Sarcophilus harrisii	62.50	5.00e-60	224.00
IUUC-Tgu-117261	Taeniopygia guttata	43.06	6.00e-103	367.00
IUUC-Tru-117705	Takifugu rubripes	45.91	4.00e-42	163.00
IUUC-Tni-120365	Tetraodon nigroviridis	47.65	1.00e-40	159.00
IUUC-Tbe-128015	Tupaia belangeri	67.13	0.00e+00	1061.00
IUUC-Ttr-128654	Tursiops truncatus	72.18	0.00e+00	1040.00
IUUC-Vpa-130176	Vicugna pacos	65.28	0.00e+00	910.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence