iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026974

Ensembl Protein ID

AAW42029

UniProt Accession

P0CS14; Q55V04; Q5KL78; DDI1_CRYNJ

Genbank Protein ID

AAW42029.1

Protein Name

DNA damage-inducible protein 1

Genbank Nucleotide ID

AE017343

Gene Name

DDI1; CNC00460

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNC00460	AAW42029	AAW42029

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	7.30e-07	27.6	398	433

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraannnleaAveyLl 39
           ed ++ lv+ G +r +a+q L+a+++n+++A+ +L+
   Q: 398  EDDIQTLVNLGAPRAQAIQLLEASGGNVDVAASMLF 433
           899********************************8 PP

Organism

Cryptococcus neoformans

Functional Description
(View)

Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Required for S-phase checkpoint control and may be involved in the regulation of exocytosis (By similarity).

Protein Sequence
(Fasta)

MRLTIIAPDS VHEHEVSPSL LIQDIINIVE ATADLPPAVI VLTSDAGTPL TDPTRTLESY 60
GLNGETATIF LTPTGPPVAS SSSIPFPDAD ADIERMRLQA LGNPSLMNDL RERDPETFAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCTCCTTC TTTAGCCTAC ACTCCTGTAT CACTGCCAAC CATGAGACTC ACGATTATTG 60
CCCCAGACTC GGTTCATGAG CACGAAGTGT CCCCTTCCTT GCTCATCCAA GACATCATCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR033322--DDI1
IPR019103--Peptidase_aspartic_DDI1-type
IPR021109--Peptidase_aspartic_dom
IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom

PROSITE

PS50030--UBA

Pfam

PF09668--Asp_protease
PF00627--UBA

SMART

SM00165--UBA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004190--F:aspartic-type endopeptidase activity
GO:0015031--P:protein transport

KEGG

cne:CNC00460

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000989	Aegilops tauschii	40.48	6.00e-64	236.00
IUUC-Aml-001440	Ailuropoda melanoleuca	44.16	3.00e-62	229.00
IUUC-Atr-002722	Amborella trichopoda	38.42	3.00e-59	220.00
IUUC-Apl-003902	Anas platyrhynchos	43.26	8.00e-55	204.00
IUUC-Aca-004811	Anolis carolinensis	52.63	3.00e-62	229.00
IUUC-Aly-006104	Arabidopsis lyrata	50.00	1.00e-16	77.40
IUUC-Ath-007673	Arabidopsis thaliana	40.18	7.00e-64	235.00
IUUC-Ago-007981	Ashbya gossypii	37.43	7.00e-58	216.00
IUUC-Acl-008073	Aspergillus clavatus	44.79	1.00e-69	254.00
IUUC-Afl-008728	Aspergillus flavus	42.74	2.00e-76	277.00
IUUC-Afu-008934	Aspergillus fumigatus	42.89	2.00e-71	261.00
IUUC-Ani-009436	Aspergillus nidulans	39.86	6.00e-76	275.00
IUUC-Ang-009596	Aspergillus niger	51.76	1.00e-65	241.00
IUUC-Aor-009968	Aspergillus oryzae	42.38	5.00e-76	276.00
IUUC-Ate-010376	Aspergillus terreus	42.08	8.00e-71	258.00
IUUC-Ame-011570	Astyanax mexicanus	43.77	2.00e-67	247.00
IUUC-Bgr-012020	Blumeria graminis	42.46	4.00e-78	283.00
IUUC-Bta-012334	Bos taurus	43.85	2.00e-61	227.00
IUUC-Bci-013907	Botrytis cinerea	46.80	6.00e-77	279.00
IUUC-Bdi-014595	Brachypodium distachyon	34.24	6.00e-64	236.00
IUUC-Bol-015258	Brassica oleracea	39.12	2.00e-63	234.00
IUUC-Bra-016740	Brassica rapa	39.76	5.00e-63	233.00
IUUC-Cel-018415	Caenorhabditis elegans	45.68	2.00e-37	148.00
IUUC-Cja-018968	Callithrix jacchus	43.85	1.00e-61	228.00
IUUC-Cfa-020530	Canis familiaris	43.56	2.00e-62	231.00
IUUC-Cpo-022103	Cavia porcellus	50.66	6.00e-52	196.00
IUUC-Cre-022841	Chlamydomonas reinhardtii	37.57	4.00e-53	200.00
IUUC-Csa-023591	Chlorocebus sabaeus	39.24	2.00e-64	239.00
IUUC-Cho-024777	Choloepus hoffmanni	34.08	9.00e-35	139.00
IUUC-Cin-025396	Ciona intestinalis	39.81	3.00e-27	112.00
IUUC-Csv-026270	Ciona savignyi	49.36	2.00e-58	217.00
IUUC-Cgl-026570	Colletotrichum gloeosporioides	57.73	2.00e-68	251.00
IUUC-Cme-027324	Cyanidioschyzon merolae	44.44	9.00e-38	148.00
IUUC-Dre-028030	Danio rerio	42.74	6.00e-66	242.00
IUUC-Dno-029264	Dasypus novemcinctus	44.03	6.00e-62	229.00
IUUC-Dor-030621	Dipodomys ordii	51.52	4.00e-14	70.50
IUUC-Dse-031180	Dothistroma septosporum	41.24	9.00e-11	59.30
IUUC-Dme-032067	Drosophila melanogaster	38.52	3.00e-61	227.00
IUUC-Ete-032664	Echinops telfairi	50.00	3.00e-46	177.00
IUUC-Eca-033648	Equus caballus	44.16	2.00e-62	231.00
IUUC-Eeu-035148	Erinaceus europaeus	50.66	5.00e-44	169.00
IUUC-Fca-035939	Felis catus	43.14	6.00e-49	186.00
IUUC-Fal-037210	Ficedula albicollis	26.61	1.00e-09	54.70
IUUC-Fox-037786	Fusarium oxysporum	60.91	9.00e-74	268.00
IUUC-Gmo-039324	Gadus morhua	41.83	7.00e-66	242.00
IUUC-Ggr-039750	Gaeumannomyces graminis	57.52	9.00e-69	252.00
IUUC-Gga-040917	Gallus gallus	56.36	9.00e-33	130.00
IUUC-Gac-041785	Gasterosteus aculeatus	41.37	2.00e-67	247.00
IUUC-Gma-043134	Glycine max	49.55	7.00e-62	229.00
IUUC-Ggo-044472	Gorilla gorilla	51.75	5.00e-47	179.00
IUUC-Hsa-046783	Homo sapiens	44.79	1.00e-63	234.00
IUUC-Hvu-047222	Hordeum vulgare	49.78	2.00e-62	231.00
IUUC-Itr-048836	Ictidomys tridecemlineatus	44.16	2.00e-62	230.00
IUUC-Kpa-049208	Komagataella pastoris	38.29	9.00e-57	212.00
IUUC-Lch-049953	Latimeria chalumnae	40.52	7.00e-62	230.00
IUUC-Lpe-050925	Leersia perrieri	37.96	3.00e-55	207.00
IUUC-Loc-052009	Lepisosteus oculatus	42.69	2.00e-65	241.00
IUUC-Lma-053305	Leptosphaeria maculans	45.89	2.00e-71	260.00
IUUC-Laf-054229	Loxodonta africana	44.48	7.00e-63	232.00
IUUC-Mcc-054796	Macaca mulatta	39.49	8.00e-65	240.00
IUUC-Meu-055944	Macropus eugenii	38.85	9.00e-45	172.00
IUUC-Mpo-057402	Magnaporthe poae	57.96	1.00e-70	258.00
IUUC-Mla-058983	Melampsora laricipopulina	41.59	6.00e-25	105.00
IUUC-Mga-059910	Meleagris gallopavo	44.59	6.00e-62	229.00
IUUC-Mvi-060225	Microbotryum violaceum	58.51	1.00e-81	295.00
IUUC-Mmr-061679	Microcebus murinus	44.77	1.00e-52	197.00
IUUC-Mdo-062992	Monodelphis domestica	44.79	2.00e-62	231.00
IUUC-Mmu-063187	Mus musculus	44.48	4.00e-62	229.00
IUUC-Mac-064640	Musa acuminata	34.00	3.00e-63	233.00
IUUC-Mpu-066770	Mustela putorius furo	42.46	2.00e-50	191.00
IUUC-Mlu-067804	Myotis lucifugus	44.13	2.00e-62	230.00
IUUC-Nfi-068555	Neosartorya fischeri	42.26	4.00e-71	259.00
IUUC-Ncr-068839	Neurospora crassa	36.82	4.00e-73	266.00
IUUC-Nle-069089	Nomascus leucogenys	38.85	3.00e-64	238.00
IUUC-Opr-070199	Ochotona princeps	51.53	3.00e-53	200.00
IUUC-Ont-072300	Oreochromis niloticus	41.42	4.00e-67	246.00
IUUC-Oan-073421	Ornithorhynchus anatinus	46.23	3.00e-64	236.00
IUUC-Ocu-074510	Oryctolagus cuniculus	51.09	3.00e-51	193.00
IUUC-Oba-075183	Oryza barthii	39.38	1.00e-64	238.00
IUUC-Obr-076044	Oryza brachyantha	43.16	1.00e-61	228.00
IUUC-Ogl-077284	Oryza glaberrima	39.09	3.00e-62	230.00
IUUC-Ogu-078171	Oryza glumaepatula	39.09	3.00e-62	230.00
IUUC-Oin-079871	Oryza indica	39.94	3.00e-64	237.00
IUUC-Olo-080579	Oryza longistaminata	39.94	5.00e-64	236.00
IUUC-Ome-081972	Oryza meridionalis	40.11	1.00e-63	234.00
IUUC-Oni-083027	Oryza nivara	39.09	3.00e-62	230.00
IUUC-Opu-083491	Oryza punctata	38.81	1.00e-61	228.00
IUUC-Oru-084589	Oryza rufipogon	39.09	3.00e-62	230.00
IUUC-Osa-085703	Oryza sativa	39.09	3.00e-62	230.00
IUUC-Ola-086911	Oryzias latipes	35.80	3.00e-30	123.00
IUUC-Olu-087654	Ostreococcus lucimarinus	49.00	3.00e-55	207.00
IUUC-Oga-089146	Otolemur garnettii	50.44	3.00e-43	166.00
IUUC-Oar-089924	Ovis aries	43.85	2.00e-61	227.00
IUUC-Ptr-090938	Pan troglodytes	44.79	1.00e-63	234.00
IUUC-Pan-091767	Papio anubis	44.16	4.00e-63	233.00
IUUC-Psi-093426	Pelodiscus sinensis	52.84	9.00e-63	231.00
IUUC-Pno-094977	Phaeosphaeria nodorum	44.26	2.00e-82	298.00
IUUC-Ppa-095744	Physcomitrella patens	38.94	2.00e-61	227.00
IUUC-Pfo-097404	Poecilia formosa	54.71	8.00e-62	228.00
IUUC-Pab-098128	Pongo abelii	44.79	1.00e-63	234.00
IUUC-Pop-099053	Populus trichocarpa	42.90	2.00e-63	234.00
IUUC-Pca-100554	Procavia capensis	49.78	1.00e-45	174.00
IUUC-Ppe-101690	Prunus persica	39.29	7.00e-63	232.00
IUUC-Pva-102638	Pteropus vampyrus	36.28	1.00e-38	152.00
IUUC-Pgr-103310	Puccinia graminis	70.49	3.00e-18	82.40
IUUC-Ptt-103798	Puccinia triticina	47.41	2.00e-85	307.00
IUUC-Pte-104408	Pyrenophora teres	45.54	4.00e-72	263.00
IUUC-Pyt-104420	Pyrenophora triticirepentis	41.05	2.00e-73	268.00
IUUC-Rno-105333	Rattus norvegicus	51.97	3.00e-61	228.00
IUUC-Sce-106167	Saccharomyces cerevisiae	40.42	2.00e-53	201.00
IUUC-Sha-107599	Sarcophilus harrisii	44.94	7.00e-63	232.00
IUUC-Sja-107968	Schizosaccharomyces japonicus	46.02	7.00e-54	202.00
IUUC-Spo-108130	Schizosaccharomyces pombe	41.50	2.00e-68	250.00
IUUC-Ssl-108671	Sclerotinia sclerotiorum	42.96	5.00e-76	276.00
IUUC-Smo-108826	Selaginella moellendorffii	25.86	3.00e-03	33.90
IUUC-Sit-109819	Setaria italica	40.36	3.00e-67	246.00
IUUC-Sly-110983	Solanum lycopersicum	41.35	1.00e-62	231.00
IUUC-Stu-112218	Solanum tuberosum	40.88	4.00e-64	236.00
IUUC-Sar-113702	Sorex araneus	29.27	3.00e-10	56.20
IUUC-Sbi-114118	Sorghum bicolor	40.77	2.00e-66	243.00
IUUC-Sre-115084	Sporisorium reilianum	38.98	2.00e-74	271.00
IUUC-Ssc-115545	Sus scrofa	43.85	8.00e-62	228.00
IUUC-Tgu-117353	Taeniopygia guttata	43.49	8.00e-61	225.00
IUUC-Tru-117838	Takifugu rubripes	56.25	3.00e-67	246.00
IUUC-Tsy-118783	Tarsius syrichta	52.17	4.00e-41	160.00
IUUC-Tni-120287	Tetraodon nigroviridis	41.82	2.00e-69	254.00
IUUC-Tca-121513	Theobroma cacao	58.08	2.00e-58	217.00
IUUC-Tvi-122402	Trichoderma virens	32.49	3.00e-08	50.80
IUUC-Tae-125471	Triticum aestivum	40.48	5.00e-64	236.00
IUUC-Tur-126159	Triticum urartu	57.99	1.00e-58	218.00
IUUC-Tme-127088	Tuber melanosporum	48.84	5.00e-86	309.00
IUUC-Tbe-127948	Tupaia belangeri	50.66	1.00e-49	188.00
IUUC-Ttr-128560	Tursiops truncatus	43.85	1.00e-61	228.00
IUUC-Uma-129478	Ustilago maydis	42.63	2.00e-68	251.00
IUUC-Vda-129758	Verticillium dahliae	49.82	6.00e-66	242.00
IUUC-Vpa-130132	Vicugna pacos	61.90	5.00e-51	192.00
IUUC-Vvi-131006	Vitis vinifera	44.19	1.00e-56	211.00
IUUC-Xtr-132758	Xenopus tropicalis	43.85	5.00e-62	229.00
IUUC-Xma-133125	Xiphophorus maculatus	54.46	2.00e-60	224.00
IUUC-Yli-134530	Yarrowia lipolytica	32.67	3.00e-60	223.00
IUUC-Zma-135856	Zea mays	39.82	1.00e-65	241.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence