iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062854

Ensembl Protein ID

ENSMODP00000026300.1

UniProt Accession

F6W0L0; F6W0L0_MONDO

Protein Name

Uncharacterized protein

Gene Name

SIK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000021031.2	ENSMODT00000026768.2	ENSMODP00000026300.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	69.15	0.00e+00	894.00	IUUC-Hsa-046775

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MVIMSEFTSV PISNQTQQRP LRVGFYDIER TLGKGNFAVV KLARHRVTKT QVAIKIIDKA 60
RLDPSNLEKI YREVQIMKLL NHPHIIKLYQ VMETKDMLYI VTEFAKNGEM FDYLTSNGHL 120

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Nucleotide Sequence
(Fasta)

GTGCAAGCCA TAACAGAAGA AAATTGCATG AAGGTTCTCT AAGTATCTCT AATCACAATC 60
GAAGCCATGG TGATCATGTC AGAATTTACC TCAGTCCCCA TTTCAAATCA GACACAGCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR034672--SIK
IPR015940--UBA

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0043276--P:anoikis
GO:0055007--P:cardiac muscle cell differentiation
GO:0032870--P:cellular response to hormone stimulus
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0035556--P:intracellular signal transduction
GO:0032792--P:negative regulation of CREB transcription factor activity
GO:0045721--P:negative regulation of gluconeogenesis
GO:0010868--P:negative regulation of triglyceride biosynthetic process
GO:0006468--P:protein phosphorylation
GO:0007346--P:regulation of mitotic cell cycle
GO:0010830--P:regulation of myotube differentiation

KEGG

mdo:100014612

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001538	Ailuropoda melanoleuca	47.07	2.00e-124	439.00
IUUC-Aca-004739	Anolis carolinensis	69.89	0.00e+00	984.00
IUUC-Ame-011603	Astyanax mexicanus	65.55	0.00e+00	738.00
IUUC-Cja-019873	Callithrix jacchus	67.97	0.00e+00	895.00
IUUC-Cfa-020801	Canis familiaris	66.79	0.00e+00	818.00
IUUC-Cpo-022296	Cavia porcellus	71.92	0.00e+00	816.00
IUUC-Csa-023676	Chlorocebus sabaeus	67.76	0.00e+00	875.00
IUUC-Cho-025021	Choloepus hoffmanni	68.38	7.00e-139	487.00
IUUC-Cin-025762	Ciona intestinalis	63.42	2.00e-126	446.00
IUUC-Csv-026013	Ciona savignyi	58.82	3.00e-120	424.00
IUUC-Dre-028021	Danio rerio	64.99	0.00e+00	735.00
IUUC-Dno-029103	Dasypus novemcinctus	67.55	0.00e+00	668.00
IUUC-Dme-031957	Drosophila melanogaster	63.88	2.00e-128	454.00
IUUC-Ete-033190	Echinops telfairi	75.62	0.00e+00	637.00
IUUC-Eca-033614	Equus caballus	57.28	5.00e-110	392.00
IUUC-Gmo-039423	Gadus morhua	62.44	0.00e+00	709.00
IUUC-Gga-040174	Gallus gallus	70.63	0.00e+00	961.00
IUUC-Gac-041875	Gasterosteus aculeatus	50.91	1.00e-167	583.00
IUUC-Ggo-045090	Gorilla gorilla	68.30	0.00e+00	878.00
IUUC-Hsa-046775	Homo sapiens	68.06	0.00e+00	877.00
IUUC-Itr-048715	Ictidomys tridecemlineatus	69.17	0.00e+00	903.00
IUUC-Lch-049933	Latimeria chalumnae	60.25	0.00e+00	815.00
IUUC-Loc-052048	Lepisosteus oculatus	58.84	0.00e+00	761.00
IUUC-Laf-054466	Loxodonta africana	69.38	0.00e+00	913.00
IUUC-Mcc-054655	Macaca mulatta	67.89	0.00e+00	876.00
IUUC-Meu-056705	Macropus eugenii	86.75	0.00e+00	933.00
IUUC-Mmr-061419	Microcebus murinus	72.04	0.00e+00	869.00
IUUC-Mmu-064252	Mus musculus	68.53	0.00e+00	950.00
IUUC-Nle-069329	Nomascus leucogenys	64.94	0.00e+00	815.00
IUUC-Opr-071101	Ochotona princeps	55.11	1.00e-159	556.00
IUUC-Ont-071887	Oreochromis niloticus	69.29	0.00e+00	658.00
IUUC-Oan-073050	Ornithorhynchus anatinus	76.05	0.00e+00	920.00
IUUC-Oga-088220	Otolemur garnettii	67.05	0.00e+00	895.00
IUUC-Oar-089420	Ovis aries	62.24	0.00e+00	756.00
IUUC-Ptr-091258	Pan troglodytes	68.19	0.00e+00	878.00
IUUC-Pan-092031	Papio anubis	67.89	0.00e+00	877.00
IUUC-Pfo-097451	Poecilia formosa	63.69	0.00e+00	697.00
IUUC-Pab-097806	Pongo abelii	68.06	0.00e+00	877.00
IUUC-Pva-102182	Pteropus vampyrus	60.89	0.00e+00	649.00
IUUC-Sha-107262	Sarcophilus harrisii	82.61	0.00e+00	1215.00
IUUC-Ssc-115584	Sus scrofa	91.53	2.00e-137	481.00
IUUC-Tgu-116973	Taeniopygia guttata	70.01	0.00e+00	954.00
IUUC-Tru-117598	Takifugu rubripes	60.66	2.00e-115	410.00
IUUC-Tsy-119567	Tarsius syrichta	45.82	1.00e-114	407.00
IUUC-Tni-120589	Tetraodon nigroviridis	59.71	1.00e-116	414.00
IUUC-Tbe-127501	Tupaia belangeri	60.48	8.00e-123	435.00
IUUC-Ttr-128365	Tursiops truncatus	69.56	0.00e+00	684.00
IUUC-Xtr-131848	Xenopus tropicalis	60.19	2.00e-110	394.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence