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Tag Content
UUCD2 ID IUUC-Ptr-090581
UUCD1 version UUC-PaT-01027
Ensembl Protein ID ENSPTRP00000025778.3
UniProt Accession H2QMM5; H2QMM5_PANTR
Genbank Protein ID ENSPTRP00000025778
Protein Name Uncharacterized protein
Genbank Nucleotide ID AACZ03025879
Gene Name UBA7
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPTRG00000014936.5 ENSPTRT00000027948.3 ENSPTRP00000025778.3
Status Unreviewed
Classification
Family E-Value Score Start End
E1 2.70e-217 721.8 396 871
Active Site
Position(s) Description Evidence
580 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU10132}
Domain Profile

   E1
   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkel 84
           YD+Qi+++G+  qekl+++++llvGag++GcEllK ++l+G+     g +tvvDmd++e snl+rqFLfr +dvg++KAevaa+a++ l
   Q: 396  YDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKIFALVGLgagnsGGLTVVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGL 484
           ***************************************************************************************** PP
   S: 85   npdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsd...dpp 167
           npd +v + ++++++++e+i+   Ff+++d+V++ald+++arr+v+ +c+++ +pl+e+gtlG++G ++v+++++te+y+++     ++
   Q: 485  NPDLQVIPLTYPLDPTTEHIYgdnFFSRVDGVAAALDSFQARRYVAARCTHYLKPLLEAGTLGTWGSATVFMPHVTEAYRAPAsaaASE 573
           ************************************************************************************999** PP
   S: 168  qktiPfctlketpnaaehtiewa........vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakt 248
           +  +P+ct++ +p++aeht++wa        +l ++++++++++++ l+++d+ ++++ +++v   l+  +++n+++++++a+ +++ +
   Q: 574  DAPYPVCTVRYFPSTAEHTLQWArhefeelfRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLRV-RPQNWQDCVAWALGHWKLC 661
           *******************************9*******************************888777.6****************** PP
   S: 249  tinsikqllksfecdivtkskspfwv................................................sfcsnaealqvpekv 289
           ++++ikqll++f++++v ++++pfw+                                                ++ ++ + +q+ +  
   Q: 662  FHYGIKQLLRHFPPNKVLEDGTPFWSgpkqcpqplefdtnqdthllyvlaaanlyaqmhglpgsqdwtalrkllKLLPQPDPQQMAPIF 750
           ***************************************************************************************** PP
   S: 290  ekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiat 371
           +++ e  +asa+     ++ l +ale ++  + +kp  l+fekddds  +vd+v aaa+lr++++gi+p +++ + k+i+g+iipaiat
   Q: 751  ASNLELASASAEfgpeqQKELNKALEVWSVGPPLKP--LMFEKDDDSnfHVDFVVAAASLRCQNYGIPP-VNRAQSKRIVGQIIPAIAT 836
           ***********9***********************9..*******************************.******************* PP
   S: 372  tnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           t+a+v+Gl+ +E++Kvv g  + +++++ +l++ae
   Q: 837  TTAAVAGLLGLELYKVVGGprPRSAFRHSYLHLAE 871
           *******************7777789988888765 PP
   
Organism Pan troglodytes
Protein Sequence
(Fasta)
YVLGSPAMQR IQGARVLVSG LQGLGAEVAK NLVLMGVGSL TLHDPHPTCW SDLAAQFLLS 60
EQDLERSRAE ASQELLAQLN RAVQVVVHTG DITEDLLLDF QVVVLTAAKL EEQLKVGTLC 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ptr-090581|E1,E1_ThiF|Pan troglodytes
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTATGTGCTG GGCTCACCTG CCATGCAGAG GATTCAGGGA GCCAGGGTCC TGGTGTCAGG 60
CCTGCAGGGC CTGGGGGCCG AGGTGGCCAA GAACTTGGTT CTGATGGGTG TGGGCAGCCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ptr-090581|E1,E1_ThiF|Pan troglodytes
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like
PROSITE

PS00865--UBIQUITIN_ACTIVAT_2
Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys
PRINTS

PR01849--UBIQUITINACT
SMART

SM00985--UBA_e1_C
Gene Ontology

GO:0005524--F:ATP binding
GO:0019782--F:ISG15 activating enzyme activity
GO:0032020--P:ISG15-protein conjugation
GO:0019941--P:modification-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001816 Ailuropoda melanoleuca 79.80 0.00e+00 1434.00
IUUC-Aca-004746 Anolis carolinensis 46.12 0.00e+00 815.00
IUUC-Ame-010933 Astyanax mexicanus 44.68 0.00e+00 769.00
IUUC-Bta-012665 Bos taurus 76.44 0.00e+00 1334.00
IUUC-Cja-019047 Callithrix jacchus 90.43 0.00e+00 1678.00
IUUC-Cfa-021225 Canis familiaris 81.07 0.00e+00 1511.00
IUUC-Cpo-022336 Cavia porcellus 71.94 0.00e+00 1306.00
IUUC-Csa-023462 Chlorocebus sabaeus 96.27 0.00e+00 1718.00
IUUC-Cho-024436 Choloepus hoffmanni 76.37 6.00e-93 335.00
IUUC-Dre-028149 Danio rerio 45.24 0.00e+00 803.00
IUUC-Dno-029347 Dasypus novemcinctus 79.86 0.00e+00 1450.00
IUUC-Dor-030997 Dipodomys ordii 75.33 0.00e+00 1348.00
IUUC-Ete-033124 Echinops telfairi 73.72 0.00e+00 910.00
IUUC-Eca-033929 Equus caballus 82.38 0.00e+00 1536.00
IUUC-Eeu-034717 Erinaceus europaeus 69.13 0.00e+00 954.00
IUUC-Fca-036564 Felis catus 82.31 0.00e+00 1488.00
IUUC-Fal-037445 Ficedula albicollis 46.05 0.00e+00 743.00
IUUC-Gmo-039338 Gadus morhua 43.91 0.00e+00 738.00
IUUC-Gga-040365 Gallus gallus 46.86 0.00e+00 742.00
IUUC-Ggo-044480 Gorilla gorilla 98.58 0.00e+00 1780.00
IUUC-Hsa-046498 Homo sapiens 99.19 0.00e+00 1793.00
IUUC-Itr-048657 Ictidomys tridecemlineatus 78.42 0.00e+00 1425.00
IUUC-Lch-050371 Latimeria chalumnae 45.17 0.00e+00 827.00
IUUC-Loc-052936 Lepisosteus oculatus 45.27 0.00e+00 806.00
IUUC-Laf-054119 Loxodonta africana 79.05 0.00e+00 1476.00
IUUC-Mcc-055597 Macaca mulatta 94.17 0.00e+00 1650.00
IUUC-Meu-056534 Macropus eugenii 54.37 0.00e+00 828.00
IUUC-Mga-060052 Meleagris gallopavo 47.98 0.00e+00 655.00
IUUC-Mmr-061405 Microcebus murinus 45.80 0.00e+00 790.00
IUUC-Mdo-063058 Monodelphis domestica 56.93 0.00e+00 995.00
IUUC-Mmu-063578 Mus musculus 73.17 0.00e+00 1375.00
IUUC-Mpu-066255 Mustela putorius furo 80.10 0.00e+00 1479.00
IUUC-Mlu-067814 Myotis lucifugus 76.37 0.00e+00 1332.00
IUUC-Nle-069193 Nomascus leucogenys 96.17 0.00e+00 1738.00
IUUC-Opr-070715 Ochotona princeps 73.41 0.00e+00 1354.00
IUUC-Ont-071671 Oreochromis niloticus 43.73 0.00e+00 784.00
IUUC-Oan-073306 Ornithorhynchus anatinus 53.49 0.00e+00 722.00
IUUC-Ocu-074162 Oryctolagus cuniculus 78.17 0.00e+00 1436.00
IUUC-Ola-087002 Oryzias latipes 45.12 0.00e+00 801.00
IUUC-Oga-088895 Otolemur garnettii 80.24 0.00e+00 1462.00
IUUC-Oar-089579 Ovis aries 76.13 0.00e+00 1327.00
IUUC-Pan-092458 Papio anubis 96.37 0.00e+00 1712.00
IUUC-Pma-094214 Petromyzon marinus 54.90 2.00e-40 158.00
IUUC-Pfo-097184 Poecilia formosa 44.69 0.00e+00 796.00
IUUC-Pab-098653 Pongo abelii 91.14 0.00e+00 1623.00
IUUC-Pca-100578 Procavia capensis 76.49 0.00e+00 882.00
IUUC-Pva-102914 Pteropus vampyrus 79.55 0.00e+00 1180.00
IUUC-Rno-106066 Rattus norvegicus 72.94 0.00e+00 1383.00
IUUC-Sha-107368 Sarcophilus harrisii 59.82 0.00e+00 1091.00
IUUC-Smo-108831 Selaginella moellendorffii 34.55 2.00e-147 516.00
IUUC-Sar-113737 Sorex araneus 46.02 0.00e+00 810.00
IUUC-Ssc-115743 Sus scrofa 81.97 0.00e+00 1479.00
IUUC-Tru-118742 Takifugu rubripes 44.29 0.00e+00 770.00
IUUC-Tni-120401 Tetraodon nigroviridis 44.19 0.00e+00 768.00
IUUC-Tbe-127587 Tupaia belangeri 74.60 0.00e+00 1186.00
IUUC-Ttr-128422 Tursiops truncatus 81.87 0.00e+00 1393.00
IUUC-Xtr-132026 Xenopus tropicalis 38.91 1.00e-172 600.00
Created Date 25-Jun-2017

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