iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011430

Ensembl Protein ID

ENSAMXP00000018251.1

UniProt Accession

W5LEI9; W5LEI9_ASTMX

Genbank Protein ID

ENSAMXP00000018251

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01001296

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000017720.1	ENSAMXT00000018251.1	ENSAMXP00000018251.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-24	84.4	1268	1302
UBD/Beta-Prp	5.70e-42	144.2	1262	1504

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gH+  v c++ +d+ll +Gs D t+kvW+l tg  
   Q: 1268 GHSKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQE 1302
           89999***99766*****************99976 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdle.tgqcl 129
           +++  +gh+++v +v+  +d  +l tgs+Drt kvw+l tg+ +++l gh ++v+s+++s s  + vs+s   +i+vwd++ + +c+
   Q: 1262 CVHVAEGHSKAVLCVDSTDD--LLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVRYSSSLVFTVSTS---YIKVWDIRdSAKCI 1343
           366679*********99999..9**************************************777777777...*******8346778 PP
   S: 130  ee......................tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng. 192
           ++                      + +g++  +n ++++p+g  l+++++  + vr+Wdl++     +ltg h ++v +l++d++g 
   Q: 1344 RTlassgqvssgdacaattnrtvtIPTGEN-QINQISLNPTGtVLYAAAG--NSVRMWDLRRFVSTGKLTG-HLGPVMCLTVDHSGn 1426
           77*******************998888888.67889****9944444444..68****************9.*********999888 PP
   S: 193  ..kelvsgsldgtvklwdlqtgecvrtlnght......dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
               +++gs+d ++k++d+ +g    +   h+      d + sv +   ++ l sgs D+ i+ Wdl ++dl +++ + +
   Q: 1427 gqDLVITGSKDHYIKMFDVTEGALGSISPTHNfepphyDGIESVVVQ--GDCLFSGSRDNGIKKWDLAHKDLQQQVPNAH 1504
           877889**************998866666666666666*********..***********************99987766 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MTTGQDESSV RVALRIRPQL AREKIEGCHI CTFVTPGEPQ VILGKDKAFT FDYVFDMDSQ 60
QDTIYSNCTE KLIEGCFEGY NATIFAYGQT GSGKTYTMGT GFDVSIPDDE LGIIPRAVSH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTGGTGAC GCATTGCGGC TCCCGGTTCG TCAGCGGCGG CGGCGCGTGA GCTTCGCTTC 60
TCCCGTCCGG CTCGCGAGCT CTCGAGCAAC GGAGTCGCTT CGGAGTGCAT AAATCTACCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	65.23	0.00e+00	1315.00
IUUC-Apl-003353	Anas platyrhynchos	66.47	0.00e+00	2086.00
IUUC-Aca-004467	Anolis carolinensis	68.32	0.00e+00	2212.00
IUUC-Bta-013485	Bos taurus	68.59	0.00e+00	1583.00
IUUC-Cpo-022297	Cavia porcellus	65.60	0.00e+00	1253.00
IUUC-Cho-024531	Choloepus hoffmanni	71.52	1.00e-176	614.00
IUUC-Cin-025160	Ciona intestinalis	38.80	7.00e-84	304.00
IUUC-Dre-028532	Danio rerio	84.26	0.00e+00	2526.00
IUUC-Dno-029972	Dasypus novemcinctus	78.57	0.00e+00	900.00
IUUC-Ete-032872	Echinops telfairi	54.08	0.00e+00	731.00
IUUC-Eca-033518	Equus caballus	64.64	0.00e+00	1279.00
IUUC-Gmo-039407	Gadus morhua	75.21	0.00e+00	1569.00
IUUC-Gga-040687	Gallus gallus	70.08	0.00e+00	2139.00
IUUC-Gac-041626	Gasterosteus aculeatus	73.90	0.00e+00	2357.00
IUUC-Hsa-046372	Homo sapiens	64.16	0.00e+00	1270.00
IUUC-Lch-050618	Latimeria chalumnae	55.70	2.00e-122	433.00
IUUC-Loc-052689	Lepisosteus oculatus	76.39	0.00e+00	2408.00
IUUC-Laf-054018	Loxodonta africana	61.44	0.00e+00	1169.00
IUUC-Mcc-055558	Macaca mulatta	64.64	0.00e+00	1280.00
IUUC-Meu-056080	Macropus eugenii	72.93	0.00e+00	824.00
IUUC-Mmr-060773	Microcebus murinus	64.56	0.00e+00	1243.00
IUUC-Mmu-063997	Mus musculus	65.32	0.00e+00	1269.00
IUUC-Opr-070188	Ochotona princeps	62.04	0.00e+00	939.00
IUUC-Ont-071938	Oreochromis niloticus	74.41	0.00e+00	2303.00
IUUC-Ola-086604	Oryzias latipes	75.54	0.00e+00	2335.00
IUUC-Oga-088799	Otolemur garnettii	65.05	0.00e+00	1300.00
IUUC-Oar-089629	Ovis aries	65.25	0.00e+00	1281.00
IUUC-Psi-093757	Pelodiscus sinensis	68.44	0.00e+00	1232.00
IUUC-Pab-097984	Pongo abelii	64.45	0.00e+00	1273.00
IUUC-Rno-105354	Rattus norvegicus	66.09	0.00e+00	1274.00
IUUC-Sha-106938	Sarcophilus harrisii	63.65	0.00e+00	1271.00
IUUC-Tgu-117076	Taeniopygia guttata	63.89	0.00e+00	1204.00
IUUC-Tru-118091	Takifugu rubripes	75.05	0.00e+00	1456.00
IUUC-Tsy-119020	Tarsius syrichta	65.03	0.00e+00	1290.00
IUUC-Tni-120813	Tetraodon nigroviridis	73.68	0.00e+00	1431.00
IUUC-Tbe-127494	Tupaia belangeri	58.24	6.00e-154	538.00
IUUC-Ttr-128393	Tursiops truncatus	64.84	0.00e+00	1282.00
IUUC-Vpa-130675	Vicugna pacos	80.76	4.00e-175	609.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence