iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049256

Ensembl Protein ID

CAY67670

UniProt Accession

C4QWP7; C4QWP7_KOMPG

Genbank Protein ID

CAY67670.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

FN392319

Gene Name

PAS_chr1-1_0294

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr1-1_0294	CAY67670	CAY67670

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.60e-38	125.4	52	88
UBD/Beta-Prp	4.00e-85	283.6	4	332

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f ++ +++vsG+dD +ikvW+l t ++l
   Q: 52   HDGPVRGVDFhPTqPYFVSGGDDYSIKVWSLQTRKCL 88
           99*********888*****************999987 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfs 103
            t +++++s  + v+f+p++++++++  ++ti++wd+++g+l+ ++++h+++v+ v+f+p+++++v+g++D+ ikvw+l+t+kc+ tl+gh d+v+++ f+
   Q: 4    LTKFESKSSKAKGVAFHPKRPWILVSLHSSTIQLWDYRMGTLIDRFEDHDGPVRGVDFHPTQPYFVSGGDDYSIKVWSLQTRKCLFTLSGHLDYVRTVFFH 104
           678899999******************************************************************************************** PP
   S: 104  psgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.................................ktgkl 171
            +  ++vs+s+d+tir+w+++++q++  +l+gh++ v+++++hp+++l+vs+slD+tvr+Wd+                                 +t+ +
   Q: 105  YDLPWIVSASDDQTIRIWNWQNRQEIA-CLTGHNHYVMSAKFHPSEDLIVSASLDQTVRVWDItglrkkhsapanmrntyedqfarqnmpqqdifgNTDAM 204
           ***************************.********************************************************************99999 PP
   S: 172  lrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisv 270
           ++   +gh++ v++ +f+++ + +vsg++d+ vk+w +++ +   v+t++ght+nv +v f+p +++++s+++D++ir Wdl +++++k++++ n++++ +
   Q: 205  VKYVLEGHDKGVNWADFHPTLPLIVSGADDRLVKIWRMSEHKAweVDTCRGHTNNVPCVLFHPTQDLIISVGEDKTIRTWDLNKRTPVKQFKRDNDRFWLI 305
           9988788********************************777778******************************************************** PP
   S: 271  avlsfgdnvlvlgsedskvniwklkknep 299
           a+ +++ n ++++  ds v+++kl++++p
   Q: 306  AA-HPEINLFATC-HDSGVMVFKLDRERP 332
           **.7777777777.589*******98876 PP

Organism

Komagataella pastoris

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MKMLTKFESK SSKAKGVAFH PKRPWILVSL HSSTIQLWDY RMGTLIDRFE DHDGPVRGVD 60
FHPTQPYFVS GGDDYSIKVW SLQTRKCLFT LSGHLDYVRT VFFHYDLPWI VSASDDQTIR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGATGC TAACCAAATT CGAATCCAAG TCTTCTAAGG CTAAGGGTGT AGCATTCCAT 60
CCTAAAAGGC CTTGGATACT TGTTTCGCTG CACTCGTCGA CGATCCAATT ATGGGATTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

ppa:PAS_chr1-1_0294

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	45.01	0.00e+00	1046.00
IUUC-Aml-001758	Ailuropoda melanoleuca	44.96	0.00e+00	1087.00
IUUC-Atr-002493	Amborella trichopoda	44.72	0.00e+00	1001.00
IUUC-Apl-003385	Anas platyrhynchos	40.52	0.00e+00	793.00
IUUC-Aca-005154	Anolis carolinensis	66.35	6.00e-87	310.00
IUUC-Aly-006020	Arabidopsis lyrata	53.24	0.00e+00	902.00
IUUC-Ath-007058	Arabidopsis thaliana	53.24	0.00e+00	901.00
IUUC-Ago-007992	Ashbya gossypii	60.02	0.00e+00	1497.00
IUUC-Acl-008027	Aspergillus clavatus	57.17	0.00e+00	1382.00
IUUC-Afl-008644	Aspergillus flavus	56.37	0.00e+00	1363.00
IUUC-Afu-008964	Aspergillus fumigatus	57.34	0.00e+00	1410.00
IUUC-Ani-009379	Aspergillus nidulans	63.73	0.00e+00	1160.00
IUUC-Ang-009756	Aspergillus niger	56.48	0.00e+00	1373.00
IUUC-Aor-010174	Aspergillus oryzae	56.37	0.00e+00	1363.00
IUUC-Ate-010302	Aspergillus terreus	56.70	0.00e+00	1413.00
IUUC-Ame-011229	Astyanax mexicanus	51.64	0.00e+00	916.00
IUUC-Bgr-012300	Blumeria graminis	53.98	0.00e+00	1298.00
IUUC-Bta-012524	Bos taurus	45.29	0.00e+00	1084.00
IUUC-Bci-013781	Botrytis cinerea	53.86	0.00e+00	1346.00
IUUC-Bdi-014549	Brachypodium distachyon	43.96	0.00e+00	1055.00
IUUC-Bol-015967	Brassica oleracea	46.05	0.00e+00	986.00
IUUC-Bra-016978	Brassica rapa	53.36	0.00e+00	899.00
IUUC-Cel-018115	Caenorhabditis elegans	50.00	0.00e+00	815.00
IUUC-Cja-019107	Callithrix jacchus	44.61	0.00e+00	1063.00
IUUC-Cfa-020675	Canis familiaris	44.37	0.00e+00	1059.00
IUUC-Cpo-021813	Cavia porcellus	45.29	0.00e+00	1098.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	52.13	0.00e+00	904.00
IUUC-Csa-023523	Chlorocebus sabaeus	45.43	0.00e+00	1097.00
IUUC-Cho-024704	Choloepus hoffmanni	58.73	3.00e-116	411.00
IUUC-Cin-025572	Ciona intestinalis	50.54	0.00e+00	887.00
IUUC-Csv-025864	Ciona savignyi	52.64	0.00e+00	862.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	63.27	0.00e+00	1157.00
IUUC-Cne-027053	Cryptococcus neoformans	49.02	0.00e+00	1110.00
IUUC-Cme-027222	Cyanidioschyzon merolae	37.95	1.00e-123	436.00
IUUC-Dre-027421	Danio rerio	44.77	0.00e+00	1084.00
IUUC-Dno-029303	Dasypus novemcinctus	44.92	0.00e+00	1096.00
IUUC-Dor-030290	Dipodomys ordii	44.06	5.00e-138	483.00
IUUC-Dse-031543	Dothistroma septosporum	52.64	0.00e+00	1266.00
IUUC-Dme-031945	Drosophila melanogaster	51.59	0.00e+00	862.00
IUUC-Ete-032873	Echinops telfairi	44.00	0.00e+00	969.00
IUUC-Eca-033773	Equus caballus	44.69	0.00e+00	1061.00
IUUC-Eeu-034874	Erinaceus europaeus	33.91	2.00e-139	488.00
IUUC-Fca-035739	Felis catus	44.34	0.00e+00	1069.00
IUUC-Fal-037263	Ficedula albicollis	41.75	0.00e+00	959.00
IUUC-Fox-037738	Fusarium oxysporum	53.12	0.00e+00	1343.00
IUUC-Fso-038153	Fusarium solani	53.60	0.00e+00	1350.00
IUUC-Gmo-039602	Gadus morhua	42.91	0.00e+00	1005.00
IUUC-Ggr-039931	Gaeumannomyces graminis	61.81	0.00e+00	1134.00
IUUC-Gga-040590	Gallus gallus	53.12	0.00e+00	932.00
IUUC-Gac-041318	Gasterosteus aculeatus	44.95	0.00e+00	1083.00
IUUC-Gma-043894	Glycine max	45.39	0.00e+00	1044.00
IUUC-Ggo-045029	Gorilla gorilla	45.02	0.00e+00	1090.00
IUUC-Hsa-046078	Homo sapiens	45.02	0.00e+00	1089.00
IUUC-Hvu-047556	Hordeum vulgare	44.70	0.00e+00	1055.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	37.00	4.00e-161	559.00
IUUC-Lch-049706	Latimeria chalumnae	44.70	0.00e+00	1068.00
IUUC-Lpe-051316	Leersia perrieri	52.62	0.00e+00	905.00
IUUC-Loc-051867	Lepisosteus oculatus	35.85	0.00e+00	712.00
IUUC-Lma-053138	Leptosphaeria maculans	62.60	0.00e+00	1150.00
IUUC-Laf-053510	Loxodonta africana	45.60	0.00e+00	1099.00
IUUC-Mcc-055836	Macaca mulatta	45.12	0.00e+00	1091.00
IUUC-Meu-056238	Macropus eugenii	48.09	0.00e+00	652.00
IUUC-Mor-057172	Magnaporthe oryzae	53.73	0.00e+00	1351.00
IUUC-Mpo-057300	Magnaporthe poae	52.06	0.00e+00	1306.00
IUUC-Mtr-058248	Medicago truncatula	44.71	0.00e+00	1048.00
IUUC-Mla-059019	Melampsora laricipopulina	49.76	0.00e+00	1194.00
IUUC-Mga-059499	Meleagris gallopavo	52.99	0.00e+00	928.00
IUUC-Mvi-060336	Microbotryum violaceum	47.86	0.00e+00	1139.00
IUUC-Mmr-061102	Microcebus murinus	44.80	0.00e+00	1085.00
IUUC-Mdo-062594	Monodelphis domestica	45.90	0.00e+00	1104.00
IUUC-Mmu-063736	Mus musculus	45.32	0.00e+00	1088.00
IUUC-Mac-065398	Musa acuminata	43.07	0.00e+00	951.00
IUUC-Mpu-066701	Mustela putorius furo	44.89	0.00e+00	1088.00
IUUC-Mlu-067392	Myotis lucifugus	45.09	0.00e+00	1087.00
IUUC-Nfi-068270	Neosartorya fischeri	57.31	0.00e+00	1395.00
IUUC-Ncr-068892	Neurospora crassa	54.29	0.00e+00	1333.00
IUUC-Nle-069634	Nomascus leucogenys	55.65	0.00e+00	809.00
IUUC-Opr-070952	Ochotona princeps	33.60	9.00e-137	479.00
IUUC-Ont-072488	Oreochromis niloticus	44.87	0.00e+00	1077.00
IUUC-Ocu-074211	Oryctolagus cuniculus	45.04	0.00e+00	1090.00
IUUC-Oba-075761	Oryza barthii	52.26	0.00e+00	904.00
IUUC-Obr-076429	Oryza brachyantha	52.50	0.00e+00	907.00
IUUC-Ogl-077364	Oryza glaberrima	52.26	0.00e+00	904.00
IUUC-Ogu-078257	Oryza glumaepatula	52.14	0.00e+00	901.00
IUUC-Oin-080029	Oryza indica	52.62	0.00e+00	909.00
IUUC-Olo-080895	Oryza longistaminata	53.16	0.00e+00	905.00
IUUC-Ome-081993	Oryza meridionalis	54.45	0.00e+00	870.00
IUUC-Oni-082874	Oryza nivara	52.32	0.00e+00	906.00
IUUC-Opu-083697	Oryza punctata	52.50	0.00e+00	908.00
IUUC-Oru-084274	Oryza rufipogon	52.26	0.00e+00	904.00
IUUC-Osa-085565	Oryza sativa	52.26	0.00e+00	904.00
IUUC-Ola-086921	Oryzias latipes	44.96	0.00e+00	1082.00
IUUC-Olu-087639	Ostreococcus lucimarinus	46.45	0.00e+00	1100.00
IUUC-Oga-087991	Otolemur garnettii	43.22	0.00e+00	1021.00
IUUC-Oar-089590	Ovis aries	45.29	0.00e+00	1093.00
IUUC-Ptr-090808	Pan troglodytes	45.02	0.00e+00	1089.00
IUUC-Pan-092475	Papio anubis	45.15	0.00e+00	1086.00
IUUC-Psi-093044	Pelodiscus sinensis	48.67	0.00e+00	780.00
IUUC-Pno-094839	Phaeosphaeria nodorum	52.50	0.00e+00	1252.00
IUUC-Ppa-095785	Physcomitrella patens	45.48	0.00e+00	1091.00
IUUC-Pfo-097493	Poecilia formosa	45.73	0.00e+00	1087.00
IUUC-Pab-098497	Pongo abelii	45.34	0.00e+00	1096.00
IUUC-Pop-099992	Populus trichocarpa	52.69	0.00e+00	892.00
IUUC-Pca-100413	Procavia capensis	49.73	3.00e-166	577.00
IUUC-Ppe-101392	Prunus persica	44.31	0.00e+00	1034.00
IUUC-Pva-102126	Pteropus vampyrus	43.68	0.00e+00	1033.00
IUUC-Pgr-103376	Puccinia graminis	48.69	0.00e+00	1208.00
IUUC-Ptt-103978	Puccinia triticina	43.92	0.00e+00	998.00
IUUC-Pte-104126	Pyrenophora teres	61.32	0.00e+00	1091.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	51.64	0.00e+00	738.00
IUUC-Rno-105428	Rattus norvegicus	45.82	0.00e+00	1098.00
IUUC-Sce-106464	Saccharomyces cerevisiae	59.50	0.00e+00	1461.00
IUUC-Sha-107301	Sarcophilus harrisii	45.20	0.00e+00	1080.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	47.34	0.00e+00	1163.00
IUUC-Spo-108217	Schizosaccharomyces pombe	50.16	0.00e+00	1224.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	53.75	0.00e+00	1345.00
IUUC-Smo-109582	Selaginella moellendorffii	53.76	0.00e+00	942.00
IUUC-Sit-109697	Setaria italica	52.38	0.00e+00	907.00
IUUC-Sly-111447	Solanum lycopersicum	44.52	0.00e+00	1054.00
IUUC-Stu-112564	Solanum tuberosum	44.96	0.00e+00	1048.00
IUUC-Sar-113313	Sorex araneus	37.36	3.00e-136	476.00
IUUC-Sbi-114388	Sorghum bicolor	44.75	0.00e+00	1049.00
IUUC-Sre-115209	Sporisorium reilianum	56.23	0.00e+00	993.00
IUUC-Ssc-115933	Sus scrofa	45.37	0.00e+00	1095.00
IUUC-Tgu-117109	Taeniopygia guttata	42.15	3.00e-84	303.00
IUUC-Tru-117772	Takifugu rubripes	44.28	0.00e+00	1064.00
IUUC-Tsy-119105	Tarsius syrichta	42.79	0.00e+00	818.00
IUUC-Tni-120556	Tetraodon nigroviridis	35.58	2.00e-123	434.00
IUUC-Tca-120918	Theobroma cacao	52.40	0.00e+00	899.00
IUUC-Tre-121951	Trichoderma reesei	53.85	0.00e+00	1317.00
IUUC-Tvi-122359	Trichoderma virens	53.93	0.00e+00	1338.00
IUUC-Tae-125527	Triticum aestivum	52.74	0.00e+00	909.00
IUUC-Tur-126754	Triticum urartu	45.48	0.00e+00	1046.00
IUUC-Tme-127170	Tuber melanosporum	56.72	0.00e+00	1434.00
IUUC-Tbe-127882	Tupaia belangeri	59.11	4.00e-114	404.00
IUUC-Ttr-128217	Tursiops truncatus	43.52	0.00e+00	1033.00
IUUC-Uma-129337	Ustilago maydis	55.84	0.00e+00	986.00
IUUC-Vda-129828	Verticillium dahliae	51.95	0.00e+00	1299.00
IUUC-Vpa-130537	Vicugna pacos	44.90	0.00e+00	1076.00
IUUC-Vvi-130958	Vitis vinifera	53.00	0.00e+00	909.00
IUUC-Xtr-132857	Xenopus tropicalis	43.96	0.00e+00	1008.00
IUUC-Xma-133138	Xiphophorus maculatus	45.65	0.00e+00	1086.00
IUUC-Yli-134399	Yarrowia lipolytica	60.47	0.00e+00	1083.00
IUUC-Zma-135612	Zea mays	44.14	0.00e+00	1055.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence