iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-110972

Ensembl Protein ID

Solyc09g018730.2.1

UniProt Accession

K4CSD5; K4CSD5_SOLLC

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc09g018730.2	Solyc09g018730.2.1	Solyc09g018730.2.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	3.80e-69	234.3	3	306

Active Site

Position(s)	Description	Evidence
63	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
138	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 27   vkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAllsvllncedklld 117
           vk++ qveelysLd + l+++ +pv gl++lFk+ + ++  r           v +d   ++ffa qvi+N+Cat+A+ls lln  d+  d
   Q: 3    VKGV-QVEELYSLDLDELNSL-RPVFGLIFLFKWRPGEKDDR----------LVIKDPNPNLFFASQVINNACATQAILSILLNSPDV--D 79
           7888.****************.**************999998..........44567789***************************9..* PP
   S: 118  lGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglkpfPldlgkk.. 206
           +G++ls lke+tk + pe k+la++n+++++ +hns+ar+e++  +e++++ +   +++++hf+sy++++g lyeldglk+ P+ lg++  
   Q: 80   IGPELSALKEFTKNFPPELKGLAINNSEAIRTAHNSFARPEPFVPEEQKAAGK---DDDVYHFISYIPVDGVLYELDGLKEGPISLGPCpg 167
           *******************************************9888886665...9*******************************977 PP
   S: 207  .keteelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkid......................keLlkLlkdieseee 274
            + + e+   ++ v+   eri+ +++ eirfnl+a+v++r+ ++t+ l+ l+                        + L k l +++s +e
   Q: 168  gQGDIEWLRMVQPVI--QERIERYSQSEIRFNLMAVVKNRKEVYTAELKELQKRrerilqqlaasqservvdssqvESLNKSLAEVNSGIE 256
           667788999999999..*****************************9987666679*******************999************* PP
   S: 275  kieaqlddekekrkkfkiddirRtenydeficifikdlaregilrklvee 324
             + ++  e+ek kk+k ++irR++ny  f++ f+k la++++lr l e+
   Q: 257  AVSDKILREEEKFKKWKTENIRRKHNYIPFLFNFLKILAEKKQLRPLIEK 306
           **********************************************9997 PP

Organism

Solanum lycopersicum

Protein Sequence
(Fasta)

MQVKGVQVEE LYSLDLDELN SLRPVFGLIF LFKWRPGEKD DRLVIKDPNP NLFFASQVIN 60
NACATQAILS ILLNSPDVDI GPELSALKEF TKNFPPELKG LAINNSEAIR TAHNSFARPE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAAGTAA AAGGTGTGCA GGTATTTTCA GTTTACTCTT AAATTATGAT TTGTTTTCTT 60
CAATCTTAGG TGGTTTAATT TCTTAGTTGT GTGGAACAGT TCCACTAAGC AACGAGAATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0010016--P:shoot system morphogenesis
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	74.19	5.00e-132	462.00
IUUC-Aml-001866	Ailuropoda melanoleuca	49.84	5.00e-78	283.00
IUUC-Atr-002966	Amborella trichopoda	80.94	2.00e-146	511.00
IUUC-Apl-003306	Anas platyrhynchos	45.43	7.00e-75	273.00
IUUC-Aca-004763	Anolis carolinensis	48.85	3.00e-77	281.00
IUUC-Aly-005581	Arabidopsis lyrata	80.45	7.00e-133	465.00
IUUC-Ath-007283	Arabidopsis thaliana	79.49	2.00e-135	474.00
IUUC-Ago-007999	Ashbya gossypii	34.84	1.00e-24	106.00
IUUC-Acl-008231	Aspergillus clavatus	53.42	1.00e-57	215.00
IUUC-Afl-008557	Aspergillus flavus	48.76	6.00e-54	203.00
IUUC-Afu-008988	Aspergillus fumigatus	52.51	1.00e-54	206.00
IUUC-Ani-009420	Aspergillus nidulans	41.10	5.00e-55	207.00
IUUC-Ang-009859	Aspergillus niger	49.33	2.00e-51	195.00
IUUC-Aor-010145	Aspergillus oryzae	48.76	6.00e-54	203.00
IUUC-Ate-010347	Aspergillus terreus	47.68	9.00e-53	199.00
IUUC-Ame-010791	Astyanax mexicanus	48.88	4.00e-80	290.00
IUUC-Bgr-012298	Blumeria graminis	40.45	1.00e-52	199.00
IUUC-Bta-013251	Bos taurus	49.84	4.00e-78	283.00
IUUC-Bci-013786	Botrytis cinerea	39.09	9.00e-55	206.00
IUUC-Bdi-014132	Brachypodium distachyon	73.72	1.00e-127	448.00
IUUC-Bol-015611	Brassica oleracea	79.49	1.00e-138	484.00
IUUC-Bra-017769	Brassica rapa	79.49	5.00e-138	482.00
IUUC-Cel-018604	Caenorhabditis elegans	41.10	5.00e-61	227.00
IUUC-Cja-019768	Callithrix jacchus	45.37	2.00e-72	265.00
IUUC-Cfa-020207	Canis familiaris	49.84	5.00e-78	283.00
IUUC-Cpo-021925	Cavia porcellus	46.91	2.00e-71	261.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	48.72	4.00e-75	273.00
IUUC-Csa-023958	Chlorocebus sabaeus	49.84	6.00e-78	283.00
IUUC-Cho-024928	Choloepus hoffmanni	58.11	1.00e-18	86.70
IUUC-Cin-025771	Ciona intestinalis	41.35	3.00e-61	227.00
IUUC-Csv-026149	Ciona savignyi	42.68	2.00e-63	234.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	38.13	6.00e-50	190.00
IUUC-Cne-026955	Cryptococcus neoformans	31.21	3.00e-39	154.00
IUUC-Cme-027104	Cyanidioschyzon merolae	28.74	2.00e-35	142.00
IUUC-Dre-027409	Danio rerio	48.24	3.00e-79	287.00
IUUC-Dno-028921	Dasypus novemcinctus	49.84	1.00e-77	282.00
IUUC-Dor-030891	Dipodomys ordii	48.59	2.00e-38	153.00
IUUC-Dse-031170	Dothistroma septosporum	37.65	5.00e-51	193.00
IUUC-Dme-031677	Drosophila melanogaster	44.66	1.00e-69	255.00
IUUC-Ete-032646	Echinops telfairi	46.61	4.00e-45	175.00
IUUC-Eca-033776	Equus caballus	49.84	4.00e-78	283.00
IUUC-Eeu-035305	Erinaceus europaeus	57.01	3.00e-31	128.00
IUUC-Fca-035846	Felis catus	45.81	2.00e-73	268.00
IUUC-Fal-037597	Ficedula albicollis	47.54	4.00e-76	276.00
IUUC-Fox-037670	Fusarium oxysporum	46.98	1.00e-45	176.00
IUUC-Fso-038243	Fusarium solani	47.91	2.00e-46	178.00
IUUC-Gmo-038499	Gadus morhua	44.92	4.00e-69	254.00
IUUC-Ggr-039975	Gaeumannomyces graminis	45.33	5.00e-46	177.00
IUUC-Gga-040904	Gallus gallus	49.20	1.00e-80	292.00
IUUC-Gac-042058	Gasterosteus aculeatus	48.20	4.00e-77	280.00
IUUC-Gma-043030	Glycine max	88.89	8.00e-162	561.00
IUUC-Ggo-044699	Gorilla gorilla	46.15	3.00e-66	244.00
IUUC-Hsa-046227	Homo sapiens	49.84	3.00e-78	284.00
IUUC-Hvu-047359	Hordeum vulgare	73.87	1.00e-130	457.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	45.27	1.00e-72	266.00
IUUC-Lch-049829	Latimeria chalumnae	49.51	6.00e-78	283.00
IUUC-Lpe-050899	Leersia perrieri	76.07	2.00e-124	437.00
IUUC-Loc-052264	Lepisosteus oculatus	48.69	4.00e-76	277.00
IUUC-Lma-053110	Leptosphaeria maculans	50.95	4.00e-48	184.00
IUUC-Laf-053639	Loxodonta africana	49.84	5.00e-78	283.00
IUUC-Mcc-055506	Macaca mulatta	49.84	6.00e-78	283.00
IUUC-Meu-056267	Macropus eugenii	46.69	4.00e-48	185.00
IUUC-Mor-057001	Magnaporthe oryzae	45.81	2.00e-50	191.00
IUUC-Mpo-057608	Magnaporthe poae	45.56	4.00e-30	123.00
IUUC-Mtr-057731	Medicago truncatula	86.67	9.00e-152	528.00
IUUC-Mla-059016	Melampsora laricipopulina	45.60	7.00e-38	149.00
IUUC-Mga-060178	Meleagris gallopavo	49.52	3.00e-81	294.00
IUUC-Mvi-060353	Microbotryum violaceum	39.17	4.00e-50	191.00
IUUC-Mmr-060738	Microcebus murinus	50.16	2.00e-78	285.00
IUUC-Mdo-062266	Monodelphis domestica	52.91	9.00e-53	198.00
IUUC-Mmu-063619	Mus musculus	49.51	2.00e-77	281.00
IUUC-Mac-065301	Musa acuminata	81.21	1.00e-149	521.00
IUUC-Mpu-066058	Mustela putorius furo	49.51	8.00e-78	283.00
IUUC-Mlu-067292	Myotis lucifugus	48.53	7.00e-77	279.00
IUUC-Nfi-068275	Neosartorya fischeri	41.44	1.00e-56	212.00
IUUC-Ncr-068713	Neurospora crassa	38.17	8.00e-50	189.00
IUUC-Nle-069013	Nomascus leucogenys	49.84	3.00e-78	284.00
IUUC-Opr-070628	Ochotona princeps	44.48	1.00e-71	262.00
IUUC-Ont-072688	Oreochromis niloticus	47.06	5.00e-76	276.00
IUUC-Oan-073004	Ornithorhynchus anatinus	53.18	5.00e-65	239.00
IUUC-Ocu-074303	Oryctolagus cuniculus	49.51	2.00e-77	282.00
IUUC-Oba-075002	Oryza barthii	74.84	5.00e-130	456.00
IUUC-Obr-076392	Oryza brachyantha	74.10	4.00e-126	443.00
IUUC-Ogl-077271	Oryza glaberrima	74.84	5.00e-130	456.00
IUUC-Ogu-078493	Oryza glumaepatula	76.77	6.00e-131	459.00
IUUC-Oin-080084	Oryza indica	76.77	6.00e-131	459.00
IUUC-Olo-080803	Oryza longistaminata	76.45	2.00e-130	457.00
IUUC-Ome-081146	Oryza meridionalis	75.81	2.00e-129	454.00
IUUC-Oni-082146	Oryza nivara	76.77	6.00e-131	459.00
IUUC-Opu-083633	Oryza punctata	74.75	4.00e-126	443.00
IUUC-Oru-084789	Oryza rufipogon	76.77	6.00e-131	459.00
IUUC-Osa-086196	Oryza sativa	76.77	6.00e-131	459.00
IUUC-Ola-087126	Oryzias latipes	48.21	4.00e-75	273.00
IUUC-Olu-087665	Ostreococcus lucimarinus	44.25	4.00e-64	237.00
IUUC-Oga-089140	Otolemur garnettii	46.11	9.00e-74	269.00
IUUC-Oar-090296	Ovis aries	49.84	3.00e-78	284.00
IUUC-Ptr-090566	Pan troglodytes	49.84	3.00e-78	284.00
IUUC-Pan-092052	Papio anubis	49.84	5.00e-78	283.00
IUUC-Psi-093723	Pelodiscus sinensis	48.85	2.00e-78	285.00
IUUC-Pma-094568	Petromyzon marinus	50.92	9.00e-63	232.00
IUUC-Pno-095120	Phaeosphaeria nodorum	50.00	1.00e-48	186.00
IUUC-Ppa-095761	Physcomitrella patens	71.91	4.00e-128	449.00
IUUC-Pfo-096210	Poecilia formosa	48.85	6.00e-78	283.00
IUUC-Pab-098463	Pongo abelii	49.84	3.00e-78	284.00
IUUC-Pop-099109	Populus trichocarpa	83.60	3.00e-152	530.00
IUUC-Pca-100108	Procavia capensis	51.80	2.00e-61	228.00
IUUC-Ppe-101176	Prunus persica	86.67	6.00e-157	545.00
IUUC-Pva-102629	Pteropus vampyrus	53.18	2.00e-63	235.00
IUUC-Pgr-103419	Puccinia graminis	45.05	1.00e-47	182.00
IUUC-Pte-104207	Pyrenophora teres	51.02	4.00e-32	129.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	50.00	1.00e-52	199.00
IUUC-Rno-105579	Rattus norvegicus	44.44	4.00e-74	270.00
IUUC-Sha-106894	Sarcophilus harrisii	50.69	6.00e-75	273.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	40.88	2.00e-54	204.00
IUUC-Spo-108371	Schizosaccharomyces pombe	41.46	1.00e-61	228.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	39.02	1.00e-49	188.00
IUUC-Smo-109396	Selaginella moellendorffii	72.76	2.00e-124	437.00
IUUC-Sit-110630	Setaria italica	74.60	2.00e-131	461.00
IUUC-Stu-112185	Solanum tuberosum	99.05	0.00e+00	634.00
IUUC-Sar-113294	Sorex araneus	53.99	2.00e-47	182.00
IUUC-Sbi-113951	Sorghum bicolor	74.60	5.00e-131	459.00
IUUC-Ssc-115501	Sus scrofa	49.51	6.00e-78	283.00
IUUC-Tgu-117152	Taeniopygia guttata	47.54	4.00e-76	276.00
IUUC-Tru-118388	Takifugu rubripes	46.89	6.00e-77	280.00
IUUC-Tsy-119109	Tarsius syrichta	49.84	4.00e-78	284.00
IUUC-Tni-120048	Tetraodon nigroviridis	46.89	5.00e-77	280.00
IUUC-Tca-121750	Theobroma cacao	87.34	8.00e-166	575.00
IUUC-Tre-122130	Trichoderma reesei	44.44	2.00e-50	191.00
IUUC-Tvi-122284	Trichoderma virens	39.86	1.00e-46	179.00
IUUC-Tae-124082	Triticum aestivum	74.52	5.00e-132	462.00
IUUC-Tur-126366	Triticum urartu	65.16	1.00e-109	389.00
IUUC-Tme-127187	Tuber melanosporum	40.68	2.00e-61	228.00
IUUC-Tbe-127619	Tupaia belangeri	44.30	1.00e-59	222.00
IUUC-Ttr-128867	Tursiops truncatus	46.96	2.00e-59	221.00
IUUC-Vda-129912	Verticillium dahliae	36.39	6.00e-49	186.00
IUUC-Vpa-130552	Vicugna pacos	52.66	3.00e-52	198.00
IUUC-Vvi-130881	Vitis vinifera	88.25	3.00e-161	560.00
IUUC-Xtr-131934	Xenopus tropicalis	49.68	4.00e-83	300.00
IUUC-Xma-133312	Xiphophorus maculatus	48.85	4.00e-78	283.00
IUUC-Yli-134487	Yarrowia lipolytica	31.80	2.00e-44	171.00
IUUC-Zma-135462	Zea mays	64.35	4.00e-108	383.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence