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Tag Content
UUCD2 ID IUUC-Mcc-055546
UUCD1 version UUC-MaM-00990
Ensembl Protein ID ENSMMUP00000029841.3
UniProt Accession F7GU37; F7GU37_MACMU
Genbank Protein ID ENSMMUP00000029841
Protein Name Uncharacterized protein
Genbank Nucleotide ID JSUE03046608
Gene Name UBE2A
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000022667.3 ENSMMUT00000031894.3 ENSMMUP00000029841.3
ENSMMUG00000022667.3 ENSMMUT00000079183.1 ENSMMUP00000056917.1
ENSMMUG00000022667.3 ENSMMUT00000069099.1 ENSMMUP00000052808.1
Status Unreviewed
Classification
Family E-Value Score Start End
E2/UBC 2.70e-54 183.8 80 214
Active Site
Position(s) Description Evidence
160 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00388}
Domain Profile

   E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
    Rl++++k+l++dpp+g+s p+++ +++ w+++i+Gpe+tp+e+g+Fkl+ief+e+YP kPP+v+f++k+fhPnvy++G++Cl+il+
   Q: 80 RLMRDFKRLQEDPPAGVSGAPSEN-NIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQ-- 165
    9**********************9.9************************************************************9.. PP
   S: 90 ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
    ++Wsp+++v+s+l+siqsll+epnp+sp+n++aa+l+++n++ey+k+v+
   Q: 166 NRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVS 214
    **********************************************996 PP
   

Organism Macaca mulatta
Protein Sequence
(Fasta)
MWFQSQIVGS APVYTGVVLS RRQTDPRLRR GSAVPLGASA SPSPASPASS ASSPAAGTRD 60
PSVCPTPDPA RDMSTPARRR LMRDFKRLQE DPPAGVSGAP SENNIMVWNA VIFGPEGTPF 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Mcc-055546|E2,E2/UBC|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGAGACTTG CCTTAACTGA TATATTGGAG TTAATGGGAG ATAGAAATCC TTGACCATGA 60
AAGTACCTGT TATTAAACAG CAGCTAGAAT TACTACCATT GTCAAGTGCC TCCTGCTTCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Mcc-055546|E2,E2/UBC|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0001741--C:XY body
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006281--P:DNA repair
GO:0033522--P:histone H2A ubiquitination
GO:0016574--P:histone ubiquitination
GO:0001701--P:in utero embryonic development
GO:0060135--P:maternal process involved in female pregnancy
GO:0008284--P:positive regulation of cell proliferation
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0000209--P:protein polyubiquitination
GO:0009411--P:response to UV

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001001 Aegilops tauschii 75.84 1.00e-69 254.00
IUUC-Atr-002862 Amborella trichopoda 79.19 1.00e-71 261.00
IUUC-Aly-005584 Arabidopsis lyrata 77.18 2.00e-70 257.00
IUUC-Ath-007149 Arabidopsis thaliana 77.18 2.00e-70 257.00
IUUC-Ame-011594 Astyanax mexicanus 100.00 4.00e-89 319.00
IUUC-Bgr-012039 Blumeria graminis 66.91 2.00e-56 210.00
IUUC-Bdi-014308 Brachypodium distachyon 78.52 5.00e-71 259.00
IUUC-Bol-016084 Brassica oleracea 78.52 3.00e-71 259.00
IUUC-Bra-016643 Brassica rapa 78.52 3.00e-71 259.00
IUUC-Cel-018244 Caenorhabditis elegans 85.91 1.00e-77 282.00
IUUC-Cja-018783 Callithrix jacchus 100.00 4.00e-89 319.00
IUUC-Cfa-020646 Canis familiaris 94.91 2.00e-110 391.00
IUUC-Cpo-021323 Cavia porcellus 99.34 6.00e-89 318.00
IUUC-Csa-023588 Chlorocebus sabaeus 100.00 4.00e-89 319.00
IUUC-Cin-025537 Ciona intestinalis 82.89 8.00e-63 232.00
IUUC-Csv-025846 Ciona savignyi 83.89 2.00e-67 247.00
IUUC-Cne-026864 Cryptococcus neoformans 71.81 5.00e-65 239.00
IUUC-Dre-028358 Danio rerio 100.00 4.00e-89 319.00
IUUC-Dme-031863 Drosophila melanogaster 88.08 7.00e-78 282.00
IUUC-Eca-033562 Equus caballus 98.05 8.00e-87 311.00
IUUC-Eeu-035191 Erinaceus europaeus 79.22 2.00e-64 237.00
IUUC-Fca-036581 Felis catus 100.00 4.00e-89 319.00
IUUC-Fal-037474 Ficedula albicollis 100.00 3.00e-69 253.00
IUUC-Gmo-038517 Gadus morhua 100.00 4.00e-89 319.00
IUUC-Gga-040588 Gallus gallus 100.00 4.00e-89 319.00
IUUC-Gac-041504 Gasterosteus aculeatus 99.34 1.00e-88 318.00
IUUC-Gma-043883 Glycine max 79.19 1.00e-71 261.00
IUUC-Ggo-044896 Gorilla gorilla 100.00 4.00e-89 319.00
IUUC-Hsa-046383 Homo sapiens 100.00 4.00e-89 319.00
IUUC-Hvu-047054 Hordeum vulgare 75.84 1.00e-69 254.00
IUUC-Itr-048507 Ictidomys tridecemlineatus 100.00 4.00e-89 319.00
IUUC-Lch-049964 Latimeria chalumnae 100.00 4.00e-89 319.00
IUUC-Lpe-051301 Leersia perrieri 79.19 1.00e-71 261.00
IUUC-Loc-051731 Lepisosteus oculatus 100.00 4.00e-89 319.00
IUUC-Laf-053680 Loxodonta africana 100.00 4.00e-89 319.00
IUUC-Meu-056231 Macropus eugenii 100.00 4.00e-89 319.00
IUUC-Mtr-058305 Medicago truncatula 79.19 9.00e-72 262.00
IUUC-Mvi-060330 Microbotryum violaceum 74.17 3.00e-59 220.00
IUUC-Mmr-060956 Microcebus murinus 98.03 6.00e-85 305.00
IUUC-Mdo-062292 Monodelphis domestica 100.00 4.00e-89 319.00
IUUC-Mmu-063680 Mus musculus 100.00 4.00e-89 319.00
IUUC-Mac-064774 Musa acuminata 79.19 2.00e-71 260.00
IUUC-Nle-069121 Nomascus leucogenys 100.00 4.00e-89 319.00
IUUC-Ont-071335 Oreochromis niloticus 98.68 2.00e-87 313.00
IUUC-Ocu-074550 Oryctolagus cuniculus 94.50 6.00e-107 379.00
IUUC-Oba-075896 Oryza barthii 78.52 5.00e-71 259.00
IUUC-Obr-076713 Oryza brachyantha 79.19 1.00e-71 261.00
IUUC-Ogl-077116 Oryza glaberrima 79.19 1.00e-71 261.00
IUUC-Ogu-078696 Oryza glumaepatula 79.19 1.00e-71 261.00
IUUC-Oin-079099 Oryza indica 79.19 1.00e-71 261.00
IUUC-Olo-081018 Oryza longistaminata 67.27 4.00e-62 230.00
IUUC-Ome-081285 Oryza meridionalis 79.19 1.00e-71 261.00
IUUC-Oni-082088 Oryza nivara 79.19 1.00e-71 261.00
IUUC-Opu-083310 Oryza punctata 79.19 1.00e-71 261.00
IUUC-Oru-084449 Oryza rufipogon 79.19 1.00e-71 261.00
IUUC-Osa-085923 Oryza sativa 79.19 1.00e-71 261.00
IUUC-Ola-086407 Oryzias latipes 100.00 4.00e-89 319.00
IUUC-Olu-087830 Ostreococcus lucimarinus 79.87 3.00e-62 229.00
IUUC-Oga-088659 Otolemur garnettii 100.00 4.00e-89 319.00
IUUC-Ptr-091305 Pan troglodytes 100.00 4.00e-89 319.00
IUUC-Pan-092740 Papio anubis 99.55 4.00e-118 416.00
IUUC-Psi-094094 Pelodiscus sinensis 100.00 4.00e-89 319.00
IUUC-Pma-094376 Petromyzon marinus 96.03 2.00e-85 307.00
IUUC-Ppa-095689 Physcomitrella patens 79.19 2.00e-62 231.00
IUUC-Pfo-096656 Poecilia formosa 99.34 6.00e-89 318.00
IUUC-Pab-097972 Pongo abelii 100.00 4.00e-89 319.00
IUUC-Pop-099517 Populus trichocarpa 79.19 1.00e-71 261.00
IUUC-Pca-100906 Procavia capensis 93.42 8.00e-81 291.00
IUUC-Ppe-101949 Prunus persica 79.19 3.00e-71 261.00
IUUC-Pva-102380 Pteropus vampyrus 98.68 2.00e-85 307.00
IUUC-Rno-105577 Rattus norvegicus 93.83 3.00e-86 310.00
IUUC-Sja-107790 Schizosaccharomyces japonicus 72.48 8.00e-59 219.00
IUUC-Spo-108073 Schizosaccharomyces pombe 72.48 6.00e-59 219.00
IUUC-Smo-109512 Selaginella moellendorffii 79.19 5.00e-72 262.00
IUUC-Sit-110731 Setaria italica 79.19 1.00e-71 261.00
IUUC-Sly-111506 Solanum lycopersicum 78.52 3.00e-71 259.00
IUUC-Stu-112080 Solanum tuberosum 78.52 3.00e-71 259.00
IUUC-Sbi-114289 Sorghum bicolor 79.19 1.00e-71 261.00
IUUC-Ssc-116265 Sus scrofa 100.00 4.00e-89 319.00
IUUC-Tgu-117383 Taeniopygia guttata 100.00 4.00e-89 319.00
IUUC-Tru-117924 Takifugu rubripes 90.74 6.00e-81 292.00
IUUC-Tni-119743 Tetraodon nigroviridis 96.05 3.00e-84 303.00
IUUC-Tca-121827 Theobroma cacao 78.52 2.00e-71 261.00
IUUC-Tae-124461 Triticum aestivum 77.85 5.00e-71 260.00
IUUC-Tur-126866 Triticum urartu 77.85 7.00e-71 259.00
IUUC-Tme-127148 Tuber melanosporum 70.39 3.00e-65 239.00
IUUC-Ttr-129050 Tursiops truncatus 99.34 2.00e-85 307.00
IUUC-Vvi-131547 Vitis vinifera 79.19 1.00e-71 262.00
IUUC-Xtr-132301 Xenopus tropicalis 100.00 4.00e-89 319.00
IUUC-Xma-133937 Xiphophorus maculatus 100.00 4.00e-89 319.00
Created Date 25-Jun-2017

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