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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046844
UUCD1 version UUC-HoS-00679
Ensembl Protein ID ENSP00000381652.4
UniProt Accession A8MUM1; A8MUM1_HUMAN
Genbank Protein ID ENSP00000381652
Protein Name Tumor-suppressing subtransferable candidate 1
Genbank Nucleotide ID AC019118
Gene Name TSSC1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000032389.12 ENST00000398659.8 ENSP00000381652.4
ENSG00000032389.12 ENST00000382125.8 ENSP00000371559.4
ENSG00000032389.12 ENST00000455162.5 ENSP00000389228.1
ENSG00000032389.12 ENST00000441271.1 ENSP00000393350.1
ENSG00000032389.12 ENST00000435721.5 ENSP00000403043.1
ENSG00000032389.12 ENST00000443925.6 ENSP00000389080.2
ENSG00000032389.12 ENST00000406835.6 ENSP00000385756.2
ENSG00000032389.12 ENST00000444776.1 ENSP00000400214.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBaseCircNet
miRTarBasemicroRNATRANSFACTargetScan
RepTarSomamiRmiRcodeRAID2
Protein-protein Interaction
HINTInWeb_IM
Disease-associated Variation
GWASdbGWAS CentralOMIM
Post-translational Modifications (PTMs)
CPLMBioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.30e-16 61.7 254 286
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlr 31
           H   v++l+f ++   +l+s++dD+++k WD+r
   Q: 254  HGQLVRDLDFnPNkqYYLASCGDDCKVKFWDTR 286
           8999*******555899**************86 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MEDDAPVIYG LEFQARALTP QTAETDAIRF LVGTQSLKYD NQIHIIDFDD ENNIINKNVL 60
LHQAGEIWHI SASPADRGVL TTCYNRTFCC VLSLDSFGAL GKSAAQLFIA LATSSDSKVL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046844|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GATGACACAT CCGAAAAATA GGAAGTGGCC ACTACGGAAG CTGTTCTGGG CCAGAAAGAC 60
TTCCAGTTTG GAGTCGTTTG CTGCGGGGAG GGAATGAATG GGCGCTGGGA ACACGCCCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046844|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001118 Aegilops tauschii 32.91 2.00e-39 156.00
IUUC-Aml-002348 Ailuropoda melanoleuca 94.35 3.00e-124 437.00
IUUC-Atr-003028 Amborella trichopoda 31.39 1.00e-48 187.00
IUUC-Apl-004211 Anas platyrhynchos 87.47 0.00e+00 652.00
IUUC-Aca-004893 Anolis carolinensis 85.75 0.00e+00 655.00
IUUC-Aly-005975 Arabidopsis lyrata 32.16 1.00e-49 190.00
IUUC-Ath-007527 Arabidopsis thaliana 31.66 1.00e-50 193.00
IUUC-Ame-010619 Astyanax mexicanus 81.40 0.00e+00 639.00
IUUC-Bta-013035 Bos taurus 83.09 0.00e+00 665.00
IUUC-Bdi-014619 Brachypodium distachyon 32.43 5.00e-52 198.00
IUUC-Bol-016581 Brassica oleracea 31.50 5.00e-50 191.00
IUUC-Bra-017885 Brassica rapa 31.83 1.00e-50 193.00
IUUC-Cel-018344 Caenorhabditis elegans 32.84 2.00e-53 203.00
IUUC-Cja-018975 Callithrix jacchus 92.51 0.00e+00 707.00
IUUC-Cfa-020214 Canis familiaris 87.92 0.00e+00 659.00
IUUC-Cpo-021363 Cavia porcellus 86.71 0.00e+00 631.00
IUUC-Cre-022554 Chlamydomonas reinhardtii 24.63 3.00e-28 119.00
IUUC-Csa-023240 Chlorocebus sabaeus 93.24 0.00e+00 666.00
IUUC-Cho-024713 Choloepus hoffmanni 89.37 0.00e+00 642.00
IUUC-Cin-025678 Ciona intestinalis 43.86 2.00e-101 362.00
IUUC-Csv-026022 Ciona savignyi 44.36 7.00e-99 353.00
IUUC-Dre-027817 Danio rerio 79.71 0.00e+00 665.00
IUUC-Dno-030097 Dasypus novemcinctus 90.10 0.00e+00 653.00
IUUC-Dme-031866 Drosophila melanogaster 36.36 7.00e-71 260.00
IUUC-Ete-032575 Echinops telfairi 76.12 3.00e-129 454.00
IUUC-Eca-034323 Equus caballus 87.00 1.00e-143 502.00
IUUC-Eeu-035217 Erinaceus europaeus 68.60 3.00e-134 471.00
IUUC-Fca-035709 Felis catus 85.71 6.00e-166 576.00
IUUC-Fal-036989 Ficedula albicollis 85.99 0.00e+00 641.00
IUUC-Gmo-038623 Gadus morhua 68.60 1.00e-151 529.00
IUUC-Gga-040157 Gallus gallus 85.99 0.00e+00 654.00
IUUC-Gac-041368 Gasterosteus aculeatus 58.18 3.00e-111 394.00
IUUC-Gma-044196 Glycine max 30.17 7.00e-48 184.00
IUUC-Ggo-044513 Gorilla gorilla 93.29 0.00e+00 674.00
IUUC-Hvu-047435 Hordeum vulgare 33.91 2.00e-53 202.00
IUUC-Itr-048726 Ictidomys tridecemlineatus 94.43 2.00e-147 514.00
IUUC-Lch-049696 Latimeria chalumnae 83.33 0.00e+00 644.00
IUUC-Lpe-050988 Leersia perrieri 32.30 4.00e-40 158.00
IUUC-Loc-052440 Lepisosteus oculatus 83.13 0.00e+00 637.00
IUUC-Laf-054088 Loxodonta africana 89.37 0.00e+00 644.00
IUUC-Mcc-055575 Macaca mulatta 96.38 0.00e+00 685.00
IUUC-Meu-056807 Macropus eugenii 69.57 6.00e-141 493.00
IUUC-Mtr-058599 Medicago truncatula 30.48 8.00e-49 187.00
IUUC-Mga-059336 Meleagris gallopavo 83.82 7.00e-177 613.00
IUUC-Mmr-061706 Microcebus murinus 90.10 0.00e+00 685.00
IUUC-Mdo-062736 Monodelphis domestica 87.44 0.00e+00 633.00
IUUC-Mmu-064265 Mus musculus 86.96 0.00e+00 690.00
IUUC-Mac-065342 Musa acuminata 30.62 9.00e-48 184.00
IUUC-Mpu-066514 Mustela putorius furo 85.99 0.00e+00 679.00
IUUC-Mlu-067072 Myotis lucifugus 91.88 2.00e-104 370.00
IUUC-Nle-069307 Nomascus leucogenys 91.06 0.00e+00 646.00
IUUC-Opr-070283 Ochotona princeps 68.84 2.00e-140 491.00
IUUC-Ont-072532 Oreochromis niloticus 77.78 1.00e-177 615.00
IUUC-Oan-073222 Ornithorhynchus anatinus 84.41 0.00e+00 635.00
IUUC-Oba-075849 Oryza barthii 33.23 1.00e-41 163.00
IUUC-Obr-076488 Oryza brachyantha 31.10 1.00e-44 173.00
IUUC-Ogl-077928 Oryza glaberrima 33.54 5.00e-44 171.00
IUUC-Ogu-077997 Oryza glumaepatula 33.23 1.00e-41 163.00
IUUC-Oin-079848 Oryza indica 33.54 1.00e-43 170.00
IUUC-Oni-082492 Oryza nivara 33.23 1.00e-41 164.00
IUUC-Oru-085119 Oryza rufipogon 33.23 2.00e-41 163.00
IUUC-Osa-086152 Oryza sativa 33.54 4.00e-44 171.00
IUUC-Ola-086694 Oryzias latipes 75.66 8.00e-180 623.00
IUUC-Olu-087749 Ostreococcus lucimarinus 33.82 3.00e-24 104.00
IUUC-Oga-088180 Otolemur garnettii 95.11 1.00e-150 525.00
IUUC-Oar-089621 Ovis aries 72.50 5.00e-141 493.00
IUUC-Ptr-091053 Pan troglodytes 88.65 0.00e+00 645.00
IUUC-Pan-091918 Papio anubis 92.75 0.00e+00 662.00
IUUC-Psi-093545 Pelodiscus sinensis 85.75 0.00e+00 635.00
IUUC-Pma-094439 Petromyzon marinus 70.00 2.00e-164 571.00
IUUC-Pfo-096127 Poecilia formosa 78.74 0.00e+00 627.00
IUUC-Pab-097916 Pongo abelii 96.14 0.00e+00 718.00
IUUC-Pop-098864 Populus trichocarpa 30.52 1.00e-47 183.00
IUUC-Pca-100797 Procavia capensis 73.67 6.00e-159 553.00
IUUC-Ppe-101796 Prunus persica 31.08 7.00e-51 194.00
IUUC-Pva-103228 Pteropus vampyrus 83.09 0.00e+00 634.00
IUUC-Rno-104877 Rattus norvegicus 86.96 0.00e+00 654.00
IUUC-Sha-106940 Sarcophilus harrisii 87.23 0.00e+00 660.00
IUUC-Smo-109355 Selaginella moellendorffii 31.92 1.00e-55 210.00
IUUC-Sit-109958 Setaria italica 33.08 3.00e-53 202.00
IUUC-Sly-111871 Solanum lycopersicum 30.10 9.00e-47 180.00
IUUC-Stu-112128 Solanum tuberosum 29.72 9.00e-45 174.00
IUUC-Sar-113084 Sorex araneus 71.91 1.00e-112 399.00
IUUC-Sbi-114122 Sorghum bicolor 33.17 2.00e-52 199.00
IUUC-Ssc-115385 Sus scrofa 81.88 1.00e-179 622.00
IUUC-Tgu-117090 Taeniopygia guttata 83.75 3.00e-177 614.00
IUUC-Tru-118548 Takifugu rubripes 76.85 0.00e+00 646.00
IUUC-Tsy-119435 Tarsius syrichta 91.06 0.00e+00 638.00
IUUC-Tni-120311 Tetraodon nigroviridis 67.31 6.00e-146 510.00
IUUC-Tca-121141 Theobroma cacao 30.75 2.00e-46 180.00
IUUC-Tae-122717 Triticum aestivum 33.91 3.00e-53 202.00
IUUC-Tbe-127623 Tupaia belangeri 72.18 4.00e-82 298.00
IUUC-Ttr-128706 Tursiops truncatus 71.74 9.00e-152 529.00
IUUC-Vvi-130871 Vitis vinifera 31.68 3.00e-45 175.00
IUUC-Xtr-131950 Xenopus tropicalis 81.40 0.00e+00 636.00
IUUC-Xma-133364 Xiphophorus maculatus 78.50 9.00e-180 622.00
Created Date 25-Jun-2017

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