iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012968

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02023865

Gene Name

UBE2R2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000000693.3	ENSBTAT00000000925.3	ENSBTAP00000000925.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.80e-49	165.6	2	140

Active Site

Position(s)	Description	Evidence
80	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk..... 87
            elk+l+++p+eg+++++vdesdl++wev+i+Gp++t Yegg+Fk++i+fp dYP++PP+++fltk++hPn+yenG+vC+sil+     
   Q: 2    LELKSLQEEPVEGFRITLVDESDLYNWEVAIFGPPNTLYEGGYFKAHIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHppvdd 90
           599********************************************************************************999999 PP
   S: 88   ......eeekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
                 ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ +++k+r 
   Q: 91   pqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMFRKWRD 140
           999*9*************************************99998875 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MLELKSLQEE PVEGFRITLV DESDLYNWEV AIFGPPNTLY EGGYFKAHIK FPIDYPYSPP 60
TFRFLTKMWH PNIYENGDVC ISILHPPVDD PQSGELPSER WNPTQNVRTI LLSVISLLNE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGGCCCTG ATGCTCGAGC TGAAATCCCT GCAGGAGGAA CCGGTGGAGG GCTTCCGGAT 60
CACCCTGGTG GATGAATCCG ACCTCTACAA CTGGGAGGTT GCCATCTTCG GACCCCCTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003563	Anas platyrhynchos	97.96	7.00e-84	302.00
IUUC-Aca-004589	Anolis carolinensis	98.42	3.00e-111	394.00
IUUC-Ame-011300	Astyanax mexicanus	95.70	2.00e-106	378.00
IUUC-Cel-018460	Caenorhabditis elegans	68.16	7.00e-73	266.00
IUUC-Cja-018764	Callithrix jacchus	100.00	2.00e-112	397.00
IUUC-Cfa-020955	Canis familiaris	100.00	2.00e-112	397.00
IUUC-Cpo-021451	Cavia porcellus	100.00	2.00e-112	397.00
IUUC-Csa-024239	Chlorocebus sabaeus	100.00	2.00e-112	397.00
IUUC-Cho-024999	Choloepus hoffmanni	81.67	6.00e-26	110.00
IUUC-Cin-025257	Ciona intestinalis	71.28	1.00e-83	302.00
IUUC-Csv-025954	Ciona savignyi	72.87	5.00e-85	306.00
IUUC-Dre-028153	Danio rerio	94.74	2.00e-107	381.00
IUUC-Dno-029368	Dasypus novemcinctus	100.00	1.00e-111	395.00
IUUC-Dor-030686	Dipodomys ordii	100.00	2.00e-112	397.00
IUUC-Dme-032106	Drosophila melanogaster	74.60	2.00e-86	312.00
IUUC-Ete-033001	Echinops telfairi	100.00	3.00e-64	236.00
IUUC-Eca-034221	Equus caballus	99.32	3.00e-84	303.00
IUUC-Fca-036381	Felis catus	98.65	8.00e-85	305.00
IUUC-Fal-037135	Ficedula albicollis	99.47	4.00e-111	393.00
IUUC-Gmo-039565	Gadus morhua	94.09	1.00e-105	375.00
IUUC-Gga-040477	Gallus gallus	98.45	2.00e-112	398.00
IUUC-Gac-041909	Gasterosteus aculeatus	93.55	2.00e-105	374.00
IUUC-Ggo-045150	Gorilla gorilla	99.47	1.00e-111	395.00
IUUC-Hsa-046611	Homo sapiens	100.00	2.00e-112	397.00
IUUC-Itr-047984	Ictidomys tridecemlineatus	92.11	8.00e-99	352.00
IUUC-Lch-050173	Latimeria chalumnae	98.95	3.00e-111	394.00
IUUC-Loc-051916	Lepisosteus oculatus	96.81	4.00e-106	377.00
IUUC-Laf-053860	Loxodonta africana	100.00	2.00e-112	397.00
IUUC-Mcc-054820	Macaca mulatta	100.00	2.00e-112	397.00
IUUC-Meu-056681	Macropus eugenii	93.68	2.00e-104	371.00
IUUC-Mmr-060666	Microcebus murinus	100.00	2.00e-112	397.00
IUUC-Mdo-062804	Monodelphis domestica	99.47	9.00e-112	395.00
IUUC-Mmu-063472	Mus musculus	100.00	2.00e-112	397.00
IUUC-Mlu-067397	Myotis lucifugus	96.20	8.00e-104	369.00
IUUC-Nle-070152	Nomascus leucogenys	99.08	1.00e-62	230.00
IUUC-Ont-071627	Oreochromis niloticus	94.12	2.00e-106	378.00
IUUC-Ocu-074229	Oryctolagus cuniculus	100.00	1.00e-111	395.00
IUUC-Ola-086587	Oryzias latipes	93.01	2.00e-105	374.00
IUUC-Oga-089161	Otolemur garnettii	100.00	8.00e-112	395.00
IUUC-Oar-089383	Ovis aries	100.00	2.00e-112	397.00
IUUC-Ptr-091096	Pan troglodytes	100.00	2.00e-112	397.00
IUUC-Pan-092560	Papio anubis	100.00	1.00e-111	395.00
IUUC-Psi-093263	Pelodiscus sinensis	98.63	2.00e-83	301.00
IUUC-Pma-094368	Petromyzon marinus	88.03	4.00e-74	270.00
IUUC-Pfo-096974	Poecilia formosa	93.55	2.00e-105	375.00
IUUC-Pab-098344	Pongo abelii	100.00	2.00e-112	397.00
IUUC-Rno-105821	Rattus norvegicus	100.00	2.00e-112	397.00
IUUC-Sha-107364	Sarcophilus harrisii	99.47	9.00e-112	395.00
IUUC-Sar-112992	Sorex araneus	96.34	2.00e-104	371.00
IUUC-Tgu-117074	Taeniopygia guttata	99.47	4.00e-111	393.00
IUUC-Tru-118641	Takifugu rubripes	92.93	5.00e-104	370.00
IUUC-Tsy-118797	Tarsius syrichta	97.10	4.00e-77	280.00
IUUC-Tni-119817	Tetraodon nigroviridis	92.47	1.00e-104	372.00
IUUC-Tbe-128014	Tupaia belangeri	100.00	2.00e-112	397.00
IUUC-Ttr-129037	Tursiops truncatus	99.46	9.00e-107	379.00
IUUC-Vpa-130680	Vicugna pacos	100.00	3.00e-83	300.00
IUUC-Xtr-131819	Xenopus tropicalis	100.00	3.00e-108	383.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence