iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062412

UUCD1 version

UUC-MoD-00181

Ensembl Protein ID

ENSMODP00000002256.3

UniProt Accession

F6SPD8; F6SPD8_MONDO

Protein Name

Uncharacterized protein

Gene Name

RNF139

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000001847.4	ENSMODT00000002301.4	ENSMODP00000002256.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.50e-08	35.2	548	586

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           CaiC+ +f +  +++pC+H fha Cl kw       + +++CP C
   Q: 548  CAICYHEFTTSARITPCNHYFHALCLRKW------LYIQDTCPMC 586
           ********999******************......********** PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAAVGAPQQV RMAQQQVWTA LEVALRVPCL FIIDAIFNSY YDASQGRFCV GLQILIRLLG 60
IFVSSVVLIL SQRSLFKFYM YSSAFLLAAT SVLVNYYASL HIDFYGAYNT SAFGIEFLPR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAACTGGCG ATAGGCGGCC GGAAACACCG ACGCCCGGAG GCCCCGCAGA AAGCCGCCCC 60
TGCCACCGCC ACCGCCGCCG CCGCCGCCAC CGCCGCCGCC GCCGCCTGCT CCTGCCGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025754--TRC8_N_dom
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13705--TRC8_N
PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0036503--P:ERAD pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0017148--P:negative regulation of translation
GO:2000060--P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0060628--P:regulation of ER to Golgi vesicle-mediated transport
GO:0070613--P:regulation of protein processing

KEGG

mdo:100026171

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002401	Ailuropoda melanoleuca	90.28	0.00e+00	1174.00
IUUC-Apl-004214	Anas platyrhynchos	87.85	0.00e+00	982.00
IUUC-Aca-005326	Anolis carolinensis	78.59	0.00e+00	975.00
IUUC-Ame-011687	Astyanax mexicanus	73.61	0.00e+00	860.00
IUUC-Bta-013394	Bos taurus	89.88	0.00e+00	1208.00
IUUC-Bci-013813	Botrytis cinerea	65.38	3.00e-07	49.70
IUUC-Cja-019499	Callithrix jacchus	89.14	0.00e+00	1199.00
IUUC-Cfa-020357	Canis familiaris	90.33	0.00e+00	1184.00
IUUC-Cpo-021924	Cavia porcellus	89.98	0.00e+00	1110.00
IUUC-Csa-023513	Chlorocebus sabaeus	89.43	0.00e+00	1192.00
IUUC-Cho-024285	Choloepus hoffmanni	84.52	0.00e+00	1056.00
IUUC-Cin-025223	Ciona intestinalis	53.56	3.00e-74	271.00
IUUC-Csv-026018	Ciona savignyi	47.32	6.00e-64	237.00
IUUC-Dre-028660	Danio rerio	67.68	0.00e+00	777.00
IUUC-Dno-029463	Dasypus novemcinctus	87.24	3.00e-155	541.00
IUUC-Dor-030728	Dipodomys ordii	89.00	0.00e+00	1078.00
IUUC-Dse-031284	Dothistroma septosporum	41.94	2.00e-09	56.60
IUUC-Dme-032186	Drosophila melanogaster	44.35	7.00e-98	351.00
IUUC-Ete-032368	Echinops telfairi	84.08	0.00e+00	1113.00
IUUC-Eca-034325	Equus caballus	90.18	0.00e+00	1162.00
IUUC-Fca-035537	Felis catus	88.89	0.00e+00	1134.00
IUUC-Fal-037459	Ficedula albicollis	87.38	0.00e+00	962.00
IUUC-Gmo-039442	Gadus morhua	77.99	6.00e-99	355.00
IUUC-Gga-041071	Gallus gallus	83.25	0.00e+00	1006.00
IUUC-Gac-042483	Gasterosteus aculeatus	66.37	0.00e+00	905.00
IUUC-Ggo-044672	Gorilla gorilla	89.14	0.00e+00	1190.00
IUUC-Hsa-045836	Homo sapiens	88.39	0.00e+00	1155.00
IUUC-Itr-048588	Ictidomys tridecemlineatus	90.36	0.00e+00	1191.00
IUUC-Lch-050073	Latimeria chalumnae	72.94	0.00e+00	985.00
IUUC-Loc-052908	Lepisosteus oculatus	71.66	0.00e+00	954.00
IUUC-Laf-053519	Loxodonta africana	87.80	0.00e+00	1198.00
IUUC-Mcc-054674	Macaca mulatta	87.94	1.00e-97	348.00
IUUC-Mor-057262	Magnaporthe oryzae	32.56	2.00e-08	55.10
IUUC-Mga-059922	Meleagris gallopavo	87.16	0.00e+00	969.00
IUUC-Mmr-061452	Microcebus murinus	88.69	0.00e+00	1165.00
IUUC-Mmu-063147	Mus musculus	87.26	0.00e+00	1164.00
IUUC-Mpu-065929	Mustela putorius furo	90.18	0.00e+00	1181.00
IUUC-Mlu-067899	Myotis lucifugus	88.24	0.00e+00	1148.00
IUUC-Nle-070083	Nomascus leucogenys	89.14	0.00e+00	1188.00
IUUC-Opr-070461	Ochotona princeps	85.63	0.00e+00	1152.00
IUUC-Ont-072256	Oreochromis niloticus	70.15	0.00e+00	914.00
IUUC-Oan-073150	Ornithorhynchus anatinus	83.97	0.00e+00	937.00
IUUC-Ocu-073748	Oryctolagus cuniculus	87.37	0.00e+00	1134.00
IUUC-Oga-088565	Otolemur garnettii	89.76	0.00e+00	1190.00
IUUC-Oar-089432	Ovis aries	91.16	0.00e+00	1129.00
IUUC-Ptr-091422	Pan troglodytes	88.99	0.00e+00	1189.00
IUUC-Pan-092331	Papio anubis	89.29	0.00e+00	1192.00
IUUC-Psi-092933	Pelodiscus sinensis	86.39	0.00e+00	963.00
IUUC-Pfo-097466	Poecilia formosa	65.49	0.00e+00	909.00
IUUC-Pab-098702	Pongo abelii	88.99	0.00e+00	1188.00
IUUC-Pca-100125	Procavia capensis	86.93	0.00e+00	1156.00
IUUC-Pva-102628	Pteropus vampyrus	89.70	0.00e+00	1179.00
IUUC-Pgr-103678	Puccinia graminis	40.58	6.00e-09	53.50
IUUC-Rno-104886	Rattus norvegicus	88.99	0.00e+00	1181.00
IUUC-Sha-106702	Sarcophilus harrisii	95.68	0.00e+00	1250.00
IUUC-Ssc-116164	Sus scrofa	88.99	0.00e+00	1191.00
IUUC-Tgu-116829	Taeniopygia guttata	85.76	0.00e+00	1000.00
IUUC-Tru-118557	Takifugu rubripes	65.77	0.00e+00	875.00
IUUC-Tsy-119399	Tarsius syrichta	87.17	0.00e+00	663.00
IUUC-Tni-120006	Tetraodon nigroviridis	64.85	0.00e+00	762.00
IUUC-Tbe-127664	Tupaia belangeri	89.55	0.00e+00	1178.00
IUUC-Ttr-129144	Tursiops truncatus	89.58	0.00e+00	1217.00
IUUC-Vpa-130226	Vicugna pacos	89.73	0.00e+00	1204.00
IUUC-Xtr-132461	Xenopus tropicalis	71.32	0.00e+00	916.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence