iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Post-translational Modifications (PTMs)
CPLM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UBL/SUMO	4.10e-33	114.3	13	92

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UBL/SUMO

   S: 5    fkapvslkvagqdGsevlfklklsaqlkklmeavYvkrinldensvrfvfngqkireqetpeelevededkiellcqksGG 85
           +  +++lkvagqdGs v+fk+k++++l+klm+a Y++r++l+++++rf+f+gq+i+e++tp++le+eded+i++++q++GG
   Q: 13   NNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKA-YCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 92
           789******************************.**********************************************9 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

TDEKPKEGVK TENNDHINLK VAGQDGSVVQ FKIKRHTPLS KLMKAYCERQ GLSMRQIRFR 60
FDGQPINETD TPAQLEMEDE DTIDVFQQQT GGVY 94

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCGACGAGA AACCCAAGGT GAGCTCCGGG CGGCTGGTGT GCGGCCTCGC GTGCGGACCG 60
GTGAGGTTGG CGCGGCCCGG GTCCGTGGGC CGAAGCCGCG CGGGACTTCC CTGGCCTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR022617--Rad60/SUMO-like_dom
IPR033950--Sumo
IPR027218--SUMO_2/3
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF11976--Rad60-SLD

SMART

SM00213--UBQ

Gene Ontology

GO:0016605--C:PML body
GO:0003723--F:RNA binding
GO:0019789--F:SUMO transferase activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001918	Ailuropoda melanoleuca	98.94	3.00e-52	195.00
IUUC-Apl-003372	Anas platyrhynchos	98.88	3.00e-49	185.00
IUUC-Aca-005284	Anolis carolinensis	98.94	3.00e-52	195.00
IUUC-Ame-011427	Astyanax mexicanus	95.70	3.00e-50	188.00
IUUC-Bta-013208	Bos taurus	97.83	2.00e-50	189.00
IUUC-Cfa-020546	Canis familiaris	98.94	3.00e-52	195.00
IUUC-Cpo-021498	Cavia porcellus	98.94	3.00e-52	195.00
IUUC-Csa-023133	Chlorocebus sabaeus	98.94	3.00e-52	195.00
IUUC-Cin-025314	Ciona intestinalis	76.92	7.00e-38	148.00
IUUC-Csv-026212	Ciona savignyi	77.17	7.00e-39	151.00
IUUC-Cme-027181	Cyanidioschyzon merolae	55.32	1.00e-23	100.00
IUUC-Dre-027994	Danio rerio	97.83	2.00e-50	189.00
IUUC-Dno-029390	Dasypus novemcinctus	98.94	1.00e-52	198.00
IUUC-Dor-030760	Dipodomys ordii	32.47	3.00e-06	45.80
IUUC-Ete-032934	Echinops telfairi	79.79	4.00e-41	158.00
IUUC-Eca-033702	Equus caballus	100.00	4.00e-52	195.00
IUUC-Fca-036393	Felis catus	92.55	2.00e-48	183.00
IUUC-Fal-037226	Ficedula albicollis	98.89	8.00e-50	187.00
IUUC-Fso-038430	Fusarium solani	51.85	9.00e-20	87.80
IUUC-Gmo-038535	Gadus morhua	91.40	2.00e-48	182.00
IUUC-Gga-040145	Gallus gallus	98.94	3.00e-52	195.00
IUUC-Gma-043216	Glycine max	53.85	2.00e-21	93.20
IUUC-Ggo-045467	Gorilla gorilla	98.94	3.00e-52	195.00
IUUC-Hsa-046419	Homo sapiens	98.94	3.00e-52	195.00
IUUC-Itr-048667	Ictidomys tridecemlineatus	95.70	8.00e-50	187.00
IUUC-Lch-050572	Latimeria chalumnae	92.22	1.00e-45	173.00
IUUC-Loc-052560	Lepisosteus oculatus	96.81	1.00e-51	193.00
IUUC-Laf-054343	Loxodonta africana	97.87	8.00e-52	194.00
IUUC-Mcc-054832	Macaca mulatta	100.00	5.00e-52	196.00
IUUC-Mtr-057722	Medicago truncatula	52.75	3.00e-21	92.80
IUUC-Mga-059768	Meleagris gallopavo	98.88	3.00e-49	185.00
IUUC-Mmr-061593	Microcebus murinus	100.00	4.00e-52	196.00
IUUC-Mdo-062678	Monodelphis domestica	97.87	4.00e-52	195.00
IUUC-Mmu-063990	Mus musculus	98.94	3.00e-52	195.00
IUUC-Mpu-065909	Mustela putorius furo	98.89	5.00e-50	188.00
IUUC-Mlu-067634	Myotis lucifugus	98.88	3.00e-49	185.00
IUUC-Ncr-068663	Neurospora crassa	51.28	8.00e-19	84.70
IUUC-Nle-069631	Nomascus leucogenys	95.74	2.00e-50	189.00
IUUC-Ont-071512	Oreochromis niloticus	95.65	4.00e-49	185.00
IUUC-Ocu-074239	Oryctolagus cuniculus	97.87	5.00e-52	194.00
IUUC-Ola-086710	Oryzias latipes	96.74	1.00e-49	186.00
IUUC-Oar-089624	Ovis aries	97.80	3.00e-50	189.00
IUUC-Ptr-091082	Pan troglodytes	98.94	3.00e-52	195.00
IUUC-Pan-091949	Papio anubis	100.00	3.00e-52	196.00
IUUC-Psi-094000	Pelodiscus sinensis	98.94	3.00e-52	195.00
IUUC-Pfo-097304	Poecilia formosa	96.74	3.00e-50	188.00
IUUC-Pab-098572	Pongo abelii	98.94	3.00e-52	195.00
IUUC-Ppe-101648	Prunus persica	51.61	9.00e-22	94.40
IUUC-Smo-109051	Selaginella moellendorffii	47.31	3.00e-20	89.40
IUUC-Sar-113337	Sorex araneus	82.80	7.00e-42	161.00
IUUC-Sbi-114801	Sorghum bicolor	53.85	2.00e-21	93.60
IUUC-Ssc-115915	Sus scrofa	98.94	3.00e-52	195.00
IUUC-Tgu-116815	Taeniopygia guttata	98.89	5.00e-50	188.00
IUUC-Tca-120927	Theobroma cacao	52.17	5.00e-21	93.20
IUUC-Tre-121926	Trichoderma reesei	49.45	3.00e-21	93.20
IUUC-Tvi-122514	Trichoderma virens	53.75	6.00e-20	88.60
IUUC-Tae-125013	Triticum aestivum	52.17	4.00e-22	95.90
IUUC-Tur-126333	Triticum urartu	40.68	2.00e-17	81.30
IUUC-Tbe-127363	Tupaia belangeri	91.40	1.00e-46	177.00
IUUC-Vda-129731	Verticillium dahliae	46.15	4.00e-19	86.30
IUUC-Vvi-131092	Vitis vinifera	53.26	1.00e-21	94.40
IUUC-Xtr-132691	Xenopus tropicalis	94.68	3.00e-50	188.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence