iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000024839.3	ENSCAFT00000044625.2	ENSCAFP00000042324.1
ENSCAFG00000024839.3	ENSCAFT00000017574.3	ENSCAFP00000016271.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-31	107.7	1543	1577
UBD/Beta-Prp	3.00e-42	145.1	1410	1613

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H+d+v++laf ++ ++l+s+++ g+ikvW+++ ++
   Q: 1543 HKDWVCALAFvPGrPMLLSACRAGVIKVWNVDNFT 1577
           ***********999****************98765 PP

UBD/Beta-Prp

   S: 51   heaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp...sgdklvsGshdrtirvwdletgqclee... 131
            e +++++ +sp+g +++ +++ +++++w+ls +++v +l+gh   v++l++ +   + d +v+Gs+d ++++++l  g+c+     
   Q: 1410 GEHQINQIALSPSG-TMLYAASGNAVRIWELSRFQPVGKLTGHIGPVMCLTVTQtasQHDLVVTGSKDHYVKMFEL--GECVTGtig 1493
           56789********9.9999**********************************998556***************65..667766779 PP
   S: 132  ....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec 214
               ++ +h + + c+++++  ++l+sGs D+ ++ Wdl++++l+++   +h+d v  l+f + ++ l+s+ + g +k+w++ + + 
   Q: 1494 pthnFEPPHYDGIECLAIQG--DILFSGSRDNGIKKWDLEQQELIQQIPNAHKDWVCALAFVPGRPMLLSACRAGVIKVWNVDNFTP 1578
           9999999************9..9*************************999************************************ PP
   S: 215  vrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
           + + +gh+++++ + +    +++ ++ssD  +++W++
   Q: 1579 IGEIRGHDSPINAICTN--AKHIFTASSDCRVKVWNY 1613
           ************77777..****************96 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAGQGDCCVK VAVRIRPQLS KEKIEGCHIC TSVTPGEPQV LLGKDKAFTY DFVFDLDTWQ 60
EQIYSTCVSK LIEGCFEGYN ATVLAYGQTG AGKTYTMGTG FDTATSEEEQ GIIPRAIAHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTCGCGCTG CGGCGGGAGG CGGCTGCAGG GCGGGAGGTG TGTGCGCGCG TGTCCGCGCC 60
GTGGGGAGCT GCGCGCCGCC GCCCGATGGC GCGAGGAGGC GCGCGGGCCG AGCCCCGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005871--C:kinesin complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	97.77	0.00e+00	2857.00
IUUC-Apl-003204	Anas platyrhynchos	76.36	0.00e+00	1582.00
IUUC-Aca-004506	Anolis carolinensis	82.72	0.00e+00	1640.00
IUUC-Ame-011515	Astyanax mexicanus	76.23	0.00e+00	1469.00
IUUC-Bta-013185	Bos taurus	76.99	0.00e+00	2166.00
IUUC-Cja-018844	Callithrix jacchus	93.97	0.00e+00	2826.00
IUUC-Cpo-022444	Cavia porcellus	94.38	0.00e+00	2850.00
IUUC-Csa-023852	Chlorocebus sabaeus	97.92	0.00e+00	2912.00
IUUC-Csv-026158	Ciona savignyi	59.00	3.00e-178	619.00
IUUC-Dre-027839	Danio rerio	75.10	0.00e+00	1453.00
IUUC-Dno-030058	Dasypus novemcinctus	93.28	0.00e+00	2778.00
IUUC-Dor-030673	Dipodomys ordii	92.85	0.00e+00	2699.00
IUUC-Ete-032705	Echinops telfairi	82.99	0.00e+00	904.00
IUUC-Eca-033885	Equus caballus	96.31	0.00e+00	2811.00
IUUC-Eeu-035338	Erinaceus europaeus	83.20	0.00e+00	2213.00
IUUC-Fca-035388	Felis catus	99.22	0.00e+00	2743.00
IUUC-Fal-037044	Ficedula albicollis	88.06	0.00e+00	2709.00
IUUC-Gmo-039034	Gadus morhua	68.52	0.00e+00	1277.00
IUUC-Gac-041328	Gasterosteus aculeatus	73.21	0.00e+00	2303.00
IUUC-Ggo-045392	Gorilla gorilla	97.45	0.00e+00	2897.00
IUUC-Hsa-046713	Homo sapiens	98.05	0.00e+00	2916.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	97.65	0.00e+00	1691.00
IUUC-Loc-052703	Lepisosteus oculatus	80.05	0.00e+00	2512.00
IUUC-Laf-054193	Loxodonta africana	87.05	0.00e+00	2501.00
IUUC-Mcc-055484	Macaca mulatta	96.27	0.00e+00	2861.00
IUUC-Meu-056278	Macropus eugenii	86.45	0.00e+00	1199.00
IUUC-Mga-059816	Meleagris gallopavo	84.54	0.00e+00	2584.00
IUUC-Mmr-061071	Microcebus murinus	93.33	0.00e+00	2781.00
IUUC-Mdo-062845	Monodelphis domestica	91.51	0.00e+00	2798.00
IUUC-Mmu-063967	Mus musculus	95.91	0.00e+00	2826.00
IUUC-Mpu-066448	Mustela putorius furo	97.50	0.00e+00	2917.00
IUUC-Nle-070037	Nomascus leucogenys	96.34	0.00e+00	2230.00
IUUC-Opr-070325	Ochotona princeps	92.16	0.00e+00	2664.00
IUUC-Ont-071851	Oreochromis niloticus	73.57	0.00e+00	2339.00
IUUC-Oan-073615	Ornithorhynchus anatinus	88.74	0.00e+00	2548.00
IUUC-Ocu-073855	Oryctolagus cuniculus	96.71	0.00e+00	2855.00
IUUC-Ola-086703	Oryzias latipes	72.35	0.00e+00	2306.00
IUUC-Oga-088171	Otolemur garnettii	94.69	0.00e+00	2806.00
IUUC-Oar-089693	Ovis aries	79.08	0.00e+00	1241.00
IUUC-Ptr-090535	Pan troglodytes	97.03	0.00e+00	1828.00
IUUC-Pan-091917	Papio anubis	97.72	0.00e+00	2679.00
IUUC-Psi-093752	Pelodiscus sinensis	78.87	0.00e+00	1414.00
IUUC-Pfo-096827	Poecilia formosa	70.69	0.00e+00	1368.00
IUUC-Pab-098441	Pongo abelii	98.05	0.00e+00	2926.00
IUUC-Pca-100781	Procavia capensis	96.03	0.00e+00	911.00
IUUC-Pva-103099	Pteropus vampyrus	92.15	0.00e+00	1362.00
IUUC-Rno-105872	Rattus norvegicus	95.12	0.00e+00	2872.00
IUUC-Sha-107097	Sarcophilus harrisii	89.70	0.00e+00	2654.00
IUUC-Ssc-115638	Sus scrofa	95.23	0.00e+00	2472.00
IUUC-Tgu-116504	Taeniopygia guttata	87.22	0.00e+00	1700.00
IUUC-Tru-118242	Takifugu rubripes	74.38	0.00e+00	1502.00
IUUC-Ttr-128824	Tursiops truncatus	90.14	0.00e+00	2266.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence