iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116884

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01057336

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000001000.1	ENSTGUT00000001037.1	ENSTGUP00000001025.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	84.33	0.00e+00	803.00	IUUC-Hsa-045784
E3 activity/RING/RING	28.37	4.00e-28	120.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

QNMVMSFRVS DLQMLLGFVG RSKSGLKHEL VTRALQLVQF DCSPEVFKKI KELYETRYNK 60
KGSEVAAPPA PHRAEALALH SSYERGGAVP RPLPAASIDY PALYGKYLNG LGRLPPKVAK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAACATGG TGATGAGTTT CCGAGTCTCA GATCTTCAGA TGTTGCTGGG TTTTGTTGGC 60
AGGAGTAAAA GCGGACTAAA ACACGAGCTA GTGACCCGAG CTTTGCAGCT GGTCCAGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	81.80	0.00e+00	789.00
IUUC-Atr-002963	Amborella trichopoda	25.05	2.00e-17	84.30
IUUC-Apl-003765	Anas platyrhynchos	87.23	0.00e+00	844.00
IUUC-Ame-010763	Astyanax mexicanus	60.69	5.00e-143	500.00
IUUC-Bta-012369	Bos taurus	84.22	0.00e+00	806.00
IUUC-Cja-019450	Callithrix jacchus	82.94	0.00e+00	796.00
IUUC-Cfa-020933	Canis familiaris	83.30	0.00e+00	796.00
IUUC-Cpo-022112	Cavia porcellus	87.67	0.00e+00	772.00
IUUC-Csa-023913	Chlorocebus sabaeus	71.99	0.00e+00	626.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	33.91	2.00e-32	132.00
IUUC-Dre-027609	Danio rerio	58.49	6.00e-138	483.00
IUUC-Dno-029664	Dasypus novemcinctus	68.56	9.00e-144	503.00
IUUC-Ete-032988	Echinops telfairi	84.57	2.00e-151	528.00
IUUC-Eca-034430	Equus caballus	83.17	0.00e+00	789.00
IUUC-Fca-035968	Felis catus	86.39	4.00e-148	516.00
IUUC-Fal-037449	Ficedula albicollis	92.99	0.00e+00	881.00
IUUC-Gmo-038925	Gadus morhua	61.15	7.00e-137	479.00
IUUC-Gga-040362	Gallus gallus	90.40	0.00e+00	860.00
IUUC-Gac-042353	Gasterosteus aculeatus	58.66	3.00e-129	454.00
IUUC-Ggo-044810	Gorilla gorilla	82.14	0.00e+00	763.00
IUUC-Hsa-045784	Homo sapiens	84.33	0.00e+00	803.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	82.57	0.00e+00	796.00
IUUC-Lch-049727	Latimeria chalumnae	70.48	9.00e-150	522.00
IUUC-Loc-052354	Lepisosteus oculatus	50.59	8.00e-122	429.00
IUUC-Laf-054261	Loxodonta africana	81.93	0.00e+00	795.00
IUUC-Mcc-054931	Macaca mulatta	83.93	0.00e+00	792.00
IUUC-Meu-056468	Macropus eugenii	84.46	0.00e+00	821.00
IUUC-Mtr-058267	Medicago truncatula	34.23	1.00e-18	87.80
IUUC-Mga-059981	Meleagris gallopavo	92.35	0.00e+00	710.00
IUUC-Mvi-060421	Microbotryum violaceum	28.64	2.00e-29	123.00
IUUC-Mmr-061181	Microcebus murinus	81.55	0.00e+00	760.00
IUUC-Mdo-062345	Monodelphis domestica	84.69	0.00e+00	826.00
IUUC-Mmu-063197	Mus musculus	79.09	0.00e+00	760.00
IUUC-Mpu-066275	Mustela putorius furo	83.07	0.00e+00	798.00
IUUC-Mlu-067194	Myotis lucifugus	83.30	0.00e+00	801.00
IUUC-Ont-072227	Oreochromis niloticus	58.43	2.00e-134	471.00
IUUC-Obr-076179	Oryza brachyantha	42.86	2.00e-20	94.40
IUUC-Ola-086865	Oryzias latipes	56.22	4.00e-133	467.00
IUUC-Oga-088945	Otolemur garnettii	83.76	0.00e+00	802.00
IUUC-Oar-089412	Ovis aries	82.68	0.00e+00	795.00
IUUC-Ptr-091550	Pan troglodytes	78.82	2.00e-166	577.00
IUUC-Pan-092183	Papio anubis	83.93	0.00e+00	801.00
IUUC-Psi-093003	Pelodiscus sinensis	88.78	0.00e+00	850.00
IUUC-Pfo-096704	Poecilia formosa	57.47	3.00e-136	478.00
IUUC-Pab-097923	Pongo abelii	89.87	0.00e+00	688.00
IUUC-Pca-100249	Procavia capensis	72.30	5.00e-137	479.00
IUUC-Pva-102562	Pteropus vampyrus	80.75	0.00e+00	762.00
IUUC-Rno-105762	Rattus norvegicus	79.68	0.00e+00	763.00
IUUC-Sce-106398	Saccharomyces cerevisiae	33.53	2.00e-28	120.00
IUUC-Sha-107253	Sarcophilus harrisii	84.49	0.00e+00	822.00
IUUC-Sja-107662	Schizosaccharomyces japonicus	30.67	8.00e-30	125.00
IUUC-Smo-109174	Selaginella moellendorffii	37.08	7.00e-14	72.40
IUUC-Sar-113149	Sorex araneus	79.69	5.00e-116	410.00
IUUC-Ssc-115241	Sus scrofa	84.02	0.00e+00	806.00
IUUC-Tru-118031	Takifugu rubripes	58.89	8.00e-141	493.00
IUUC-Tni-119766	Tetraodon nigroviridis	57.81	6.00e-137	480.00
IUUC-Ttr-128556	Tursiops truncatus	75.66	0.00e+00	661.00
IUUC-Xtr-131866	Xenopus tropicalis	76.68	0.00e+00	751.00
IUUC-Xma-133963	Xiphophorus maculatus	57.74	2.00e-129	455.00
IUUC-Yli-134583	Yarrowia lipolytica	28.92	3.00e-20	93.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence