iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066847

Ensembl Protein ID

ENSMPUP00000007675.1

UniProt Accession

M3Y8L8; M3Y8L8_MUSPF

Genbank Protein ID

ENSMPUP00000007675

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01029558

Gene Name

USP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000007732.1	ENSMPUT00000007798.1	ENSMPUP00000007675.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.80e-85	285.7	81	784

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkg..........ellkslqklfeel.......w..... 61
           +Gl+NlgNtCY+NS+LQ+L+++p +++ +++      +kke+l++e ++++kg          el++slq+l+ ++       +     
   Q: 81   VGLNNLGNTCYLNSILQVLYFCPGFKSGVKHlfniisRKKEALKDETNQKDKGnckedslasyELICSLQSLIISVeqlqasfLlnpek 169
           6***********************************9999999999998888899999999*999999999999995555555144555 PP
   S: 62   kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsde.... 129
           ++++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++e+++                  ek ++ke            e    
   Q: 170  YTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLlkkeevknvvelstkveEKPHQKE------------Emsgi 246
           88888*****************************************55555555555544444444444444............14444 PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 247  nsiemdnlrhsedykekltkgngkrkndtefgnmkkkvkvskehqsleenqrqtrskrkatgdtleipskiipkyvsenesarpsqkks 335
           56666666********************************************************************************* PP
   S: 130  ..............................................................................aeekkkkknk. 139
                                                                                               +k+  
   Q: 336  rvkinwlkpaakqpsilskfcslgkittnqgskgqlkeneydleedlgkcendnttngcelespgnnvkpvnvnevkpI-----NKGAe 419
           *****************************************************************99999998544443.....44445 PP
   S: 140  ....slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenkyycek 210
               +l+++lFqgql  +++clec++ ++r+e+f+d+s+pv+++e +k e              +l++++++f++ e++ ge+ky+ce+
   Q: 420  qigfELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEesseispepktemkTLRWAISQFASVERIVGEDKYFCEN 508
           5666*****************************************99998*************************************** PP
   S: 211  ckkkqeaekklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssG 293
           c++++eae++l ++k+Pev+++hLk+f     +f+++++  +kin+ + +pl+L+l+++ t+p+     +++Y L+avv+HsG ++ssG
   Q: 509  CHHYTEAERSLLFDKMPEVITIHLKCFaasglEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPT-----NDSYGLFAVVMHSGiTISSG 592
           **************************************************************99.....678***************** PP
   S: 294  HYvayvkn................................................................................. 301
           HY+a vk                                                                                  
   Q: 593  HYTASVKVtdlnsleldkgnfvidqmceigkpeplneeeargvvenyddeevsirvsgntqpskvlnkknveaigllggqkskadyely 681
           ***************************************************************************************** PP
   S: 302  .............................................................ekgkWllfdDskVtevkeeevleetg.. 327
                                                                         +gkWllfdDs+V++++e+++l++ +  
   Q: 682  nkasnsdkvastafaenrnsetnntngthefdtnkessdqtginfsgfenkisyvvqslkeYEGKWLLFDDSEVKVTEEKDFLNSLSps 770
           *************************9999999999999999999999988888888877766999*******************888** PP
   S: 328  ....staYvlfYkr 337
               st+Y+lfYk+
   Q: 771  tsptSTPYLLFYKK 784
           ************97 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MPGVIPTESN GLSRGSPSKK NRLSLKFFQK KETKRALDFT ESQENEEKAS EYRGSEIDQV 60
VPAAQSSPIN CEKRENLLPF VGLNNLGNTC YLNSILQVLY FCPGFKSGVK HLFNIISRKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTTCCTAA GCCTCTGATT GAAACGAATT TCAGGATTGC ACATAAAAGC CTGATGAACC 60
TGTTCATAAC TATTACAAAA GAGTCCAAAT TGCTTTTTAA GAATTCTGGT CTTCCAGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	97.46	0.00e+00	1483.00
IUUC-Apl-004204	Anas platyrhynchos	73.55	0.00e+00	952.00
IUUC-Aca-004637	Anolis carolinensis	66.12	0.00e+00	939.00
IUUC-Ame-011718	Astyanax mexicanus	48.49	8.00e-174	603.00
IUUC-Bta-012552	Bos taurus	93.38	0.00e+00	1432.00
IUUC-Cja-019588	Callithrix jacchus	94.90	0.00e+00	1483.00
IUUC-Cfa-020211	Canis familiaris	97.83	0.00e+00	1497.00
IUUC-Cpo-021551	Cavia porcellus	82.93	0.00e+00	1262.00
IUUC-Csa-024186	Chlorocebus sabaeus	94.65	0.00e+00	1481.00
IUUC-Cho-024739	Choloepus hoffmanni	84.27	0.00e+00	766.00
IUUC-Dre-028184	Danio rerio	48.96	2.00e-176	612.00
IUUC-Dno-029669	Dasypus novemcinctus	90.61	0.00e+00	1402.00
IUUC-Dor-030168	Dipodomys ordii	86.29	0.00e+00	1247.00
IUUC-Dme-031732	Drosophila melanogaster	28.77	8.00e-18	86.30
IUUC-Ete-032825	Echinops telfairi	87.33	0.00e+00	968.00
IUUC-Eca-033595	Equus caballus	93.68	0.00e+00	1360.00
IUUC-Eeu-034877	Erinaceus europaeus	81.89	4.00e-165	574.00
IUUC-Fca-035381	Felis catus	96.49	0.00e+00	1049.00
IUUC-Fal-037592	Ficedula albicollis	69.51	0.00e+00	977.00
IUUC-Gmo-039680	Gadus morhua	45.18	7.00e-154	537.00
IUUC-Gga-041196	Gallus gallus	73.16	0.00e+00	1077.00
IUUC-Gac-042292	Gasterosteus aculeatus	45.21	4.00e-153	535.00
IUUC-Ggo-044671	Gorilla gorilla	94.90	0.00e+00	1488.00
IUUC-Hsa-047020	Homo sapiens	94.78	0.00e+00	1483.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	85.37	0.00e+00	1265.00
IUUC-Lch-050543	Latimeria chalumnae	58.21	0.00e+00	706.00
IUUC-Loc-052338	Lepisosteus oculatus	52.59	0.00e+00	701.00
IUUC-Laf-053707	Loxodonta africana	91.63	0.00e+00	1434.00
IUUC-Mcc-055885	Macaca mulatta	94.90	0.00e+00	1486.00
IUUC-Meu-056573	Macropus eugenii	66.83	0.00e+00	960.00
IUUC-Mga-059346	Meleagris gallopavo	73.65	0.00e+00	1027.00
IUUC-Mmr-061612	Microcebus murinus	94.01	0.00e+00	1401.00
IUUC-Mdo-062887	Monodelphis domestica	72.24	0.00e+00	1054.00
IUUC-Mmu-064044	Mus musculus	87.40	0.00e+00	1355.00
IUUC-Mlu-067684	Myotis lucifugus	91.74	0.00e+00	1431.00
IUUC-Nle-070057	Nomascus leucogenys	94.90	0.00e+00	1488.00
IUUC-Opr-070463	Ochotona princeps	83.29	0.00e+00	1248.00
IUUC-Ont-071975	Oreochromis niloticus	46.30	1.00e-153	536.00
IUUC-Oan-073062	Ornithorhynchus anatinus	88.78	2.00e-48	184.00
IUUC-Ocu-074840	Oryctolagus cuniculus	93.38	0.00e+00	1438.00
IUUC-Ola-087088	Oryzias latipes	47.26	2.00e-176	612.00
IUUC-Oga-088472	Otolemur garnettii	92.36	0.00e+00	1426.00
IUUC-Oar-089498	Ovis aries	93.25	0.00e+00	1428.00
IUUC-Ptr-091395	Pan troglodytes	94.90	0.00e+00	1485.00
IUUC-Pan-092462	Papio anubis	95.03	0.00e+00	1486.00
IUUC-Psi-093583	Pelodiscus sinensis	73.25	0.00e+00	935.00
IUUC-Pma-094644	Petromyzon marinus	38.16	1.00e-28	119.00
IUUC-Pfo-096314	Poecilia formosa	46.76	2.00e-168	586.00
IUUC-Pab-098568	Pongo abelii	95.41	0.00e+00	1495.00
IUUC-Pca-100948	Procavia capensis	82.47	0.00e+00	1265.00
IUUC-Pva-102853	Pteropus vampyrus	93.75	0.00e+00	1445.00
IUUC-Rno-105573	Rattus norvegicus	88.41	0.00e+00	1348.00
IUUC-Sha-107495	Sarcophilus harrisii	71.73	0.00e+00	893.00
IUUC-Sar-113545	Sorex araneus	77.42	0.00e+00	1105.00
IUUC-Ssc-115962	Sus scrofa	94.55	0.00e+00	1469.00
IUUC-Tgu-116731	Taeniopygia guttata	70.20	0.00e+00	992.00
IUUC-Tru-117893	Takifugu rubripes	46.17	2.00e-158	553.00
IUUC-Tsy-119644	Tarsius syrichta	84.06	0.00e+00	1260.00
IUUC-Tni-119819	Tetraodon nigroviridis	44.78	5.00e-173	601.00
IUUC-Tbe-127272	Tupaia belangeri	89.30	0.00e+00	1272.00
IUUC-Ttr-128404	Tursiops truncatus	94.52	0.00e+00	1464.00
IUUC-Vpa-130205	Vicugna pacos	93.49	0.00e+00	1448.00
IUUC-Xtr-132613	Xenopus tropicalis	56.18	0.00e+00	753.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence