iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001467

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01000429

Gene Name

MDM4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000001126.1	ENSAMET00000001249.1	ENSAMEP00000001201.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	92.89	0.00e+00	806.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MTSFSTSAQC STSDSACRIS PEQTNQVRPK QPLLKILQAA GAQGEMFTVK EVMHYLGQYI 60
MVKQLYDQQE QHMVYCGGDL LGELLGRQSF SVKDPSPLYD MLRKNLVSLA SAATDAAQTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACATCAT TTTCTACTTC TGCCCAGTGT TCAACTTCTG ACAGTGCTTG CAGAATCTCT 60
CCAGAACAAA CCAATCAGGT AAATCATTTT TAGGCATTCC TAGTTTTCTG TAAGCTTTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

KEGG

aml:100466328

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003800	Anas platyrhynchos	60.85	3.00e-156	545.00
IUUC-Aca-004608	Anolis carolinensis	56.60	2.00e-141	495.00
IUUC-Ame-010869	Astyanax mexicanus	47.58	5.00e-111	394.00
IUUC-Bta-013287	Bos taurus	91.46	0.00e+00	882.00
IUUC-Cja-019305	Callithrix jacchus	90.45	0.00e+00	815.00
IUUC-Cfa-020393	Canis familiaris	96.75	0.00e+00	876.00
IUUC-Cpo-022166	Cavia porcellus	88.65	0.00e+00	754.00
IUUC-Csa-023654	Chlorocebus sabaeus	92.68	0.00e+00	809.00
IUUC-Cho-024403	Choloepus hoffmanni	88.81	2.00e-126	445.00
IUUC-Dre-027754	Danio rerio	48.52	2.00e-120	425.00
IUUC-Dno-029630	Dasypus novemcinctus	88.44	0.00e+00	846.00
IUUC-Dor-031064	Dipodomys ordii	69.11	0.00e+00	660.00
IUUC-Ete-032901	Echinops telfairi	79.31	0.00e+00	766.00
IUUC-Eca-034234	Equus caballus	95.12	0.00e+00	948.00
IUUC-Eeu-035015	Erinaceus europaeus	66.13	6.00e-165	573.00
IUUC-Fca-036587	Felis catus	95.93	0.00e+00	878.00
IUUC-Fal-036906	Ficedula albicollis	52.64	1.00e-137	482.00
IUUC-Gmo-038646	Gadus morhua	44.64	4.00e-98	352.00
IUUC-Gga-040124	Gallus gallus	59.06	2.00e-115	408.00
IUUC-Gac-042397	Gasterosteus aculeatus	47.26	7.00e-111	394.00
IUUC-Ggo-045505	Gorilla gorilla	92.68	0.00e+00	830.00
IUUC-Hsa-046950	Homo sapiens	92.89	0.00e+00	834.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	89.23	0.00e+00	829.00
IUUC-Lch-050141	Latimeria chalumnae	55.16	8.00e-126	443.00
IUUC-Loc-051921	Lepisosteus oculatus	49.90	2.00e-118	419.00
IUUC-Laf-054281	Loxodonta africana	86.79	0.00e+00	791.00
IUUC-Mcc-055462	Macaca mulatta	89.05	0.00e+00	759.00
IUUC-Meu-056294	Macropus eugenii	72.27	8.00e-148	516.00
IUUC-Mga-059924	Meleagris gallopavo	60.53	2.00e-168	585.00
IUUC-Mmr-061428	Microcebus murinus	90.65	0.00e+00	865.00
IUUC-Mdo-062643	Monodelphis domestica	75.90	0.00e+00	729.00
IUUC-Mmu-063229	Mus musculus	83.13	0.00e+00	787.00
IUUC-Mpu-065782	Mustela putorius furo	94.93	0.00e+00	864.00
IUUC-Mlu-068105	Myotis lucifugus	82.76	0.00e+00	791.00
IUUC-Nle-069549	Nomascus leucogenys	93.09	0.00e+00	835.00
IUUC-Opr-070568	Ochotona princeps	89.06	0.00e+00	777.00
IUUC-Ont-072276	Oreochromis niloticus	47.30	1.00e-119	423.00
IUUC-Oan-072787	Ornithorhynchus anatinus	73.99	0.00e+00	667.00
IUUC-Ocu-074912	Oryctolagus cuniculus	89.84	0.00e+00	827.00
IUUC-Ola-087037	Oryzias latipes	45.22	1.00e-99	356.00
IUUC-Oga-088953	Otolemur garnettii	86.90	0.00e+00	805.00
IUUC-Oar-089202	Ovis aries	90.85	0.00e+00	881.00
IUUC-Ptr-090964	Pan troglodytes	93.09	0.00e+00	835.00
IUUC-Pan-091975	Papio anubis	92.48	0.00e+00	825.00
IUUC-Psi-093558	Pelodiscus sinensis	61.79	3.00e-163	568.00
IUUC-Pfo-096454	Poecilia formosa	48.77	2.00e-115	409.00
IUUC-Pab-098123	Pongo abelii	93.09	0.00e+00	838.00
IUUC-Pca-101112	Procavia capensis	78.70	0.00e+00	733.00
IUUC-Pva-103098	Pteropus vampyrus	81.50	0.00e+00	774.00
IUUC-Rno-105930	Rattus norvegicus	83.77	0.00e+00	765.00
IUUC-Sha-107512	Sarcophilus harrisii	73.63	0.00e+00	645.00
IUUC-Sar-113584	Sorex araneus	82.72	0.00e+00	727.00
IUUC-Tgu-116766	Taeniopygia guttata	56.21	5.00e-101	360.00
IUUC-Tru-117829	Takifugu rubripes	48.57	2.00e-117	416.00
IUUC-Tsy-119268	Tarsius syrichta	77.85	0.00e+00	689.00
IUUC-Tni-120204	Tetraodon nigroviridis	47.14	6.00e-112	397.00
IUUC-Tbe-127840	Tupaia belangeri	83.23	6.00e-125	440.00
IUUC-Ttr-128863	Tursiops truncatus	90.65	0.00e+00	851.00
IUUC-Vpa-130718	Vicugna pacos	93.13	0.00e+00	828.00
IUUC-Xtr-132320	Xenopus tropicalis	46.94	8.00e-92	330.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence