iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010713

Ensembl Protein ID

ENSAMXP00000007010.1

UniProt Accession

W5KHE8; W5KHE8_ASTMX

Genbank Protein ID

ENSAMXP00000007010

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01013588

Gene Name

EML6 (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000006744.1	ENSAMXT00000007010.1	ENSAMXP00000007010.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-54	179.2	1692	1724
UBD/Beta-Prp	2.30e-119	398.2	58	265

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           +++++l+  ++ ++++s+sdDgti++WDl + +
   Q: 1692 GRIWGLSThPSkDIFISASDDGTIRIWDLADKK 1724
           4588888787779***************98765 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvht 89
            gh+++ i+ ++ +pdk ++atg  ++d  i vwd  t  +++ l   h+ +v+++ f+ dg+ lv+++ D  +t+ vwd ++g  + t
   Q: 58   LGHNDDIIS-LALHPDKIQVATGqvGKDPYICVWDSYTLITVSILrDVHTHGVACLAFDADGQRLVSVGLDakNTVSVWDWKKGRVLAT 145
           578899998.9999********95558999***************889***************************************** PP
   S: 90   lkghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkll 172
            +gh+d++ ++s++p   ++lvs + ++ i+ w l  +    +     ++g  +++ c+++   +  +  sG+l++ + +W+    +l+
   Q: 146  ATGHSDRIFDISWDPFLpHRLVSCG-VKHIKFWTLCGNALTPKrgifGKTGDLQTILCLAT--AKeEVTYSGALNGDIYVWKG--LNLV 229
           ***************6649999988.*********99999999995545555555555555..4449999***********66..99** PP
   S: 173  rtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq 210
           rt + +h   + s+   ++g  +++g++dg v+lwd+ 
   Q: 230  RTVQAAHGAGIFSMHACEEG--FATGGRDGCVRLWDVD 265
           ***************99965..**************85 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MADKTAPRCQ LRLEWIHGYR GHQCRNNLFY TAGKEIVYFV AGVGVVYNTR EHSQKFYLGH 60
NDDIISLALH PDKIQVATGQ VGKDPYICVW DSYTLITVSI LRDVHTHGVA CLAFDADGQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCAAGGCTT AAGCCCAGAC CCTGTTTGAG TCATCTGCGC TGCGCTGAAT TCGGTTTTAG 60
GAGGGATTAA GCACAGAAAA CGAGCGGCGC GGATTTGTGC TGATTTTTGC TCCCTTTTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	80.39	0.00e+00	3200.00
IUUC-Apl-003604	Anas platyrhynchos	80.65	0.00e+00	3189.00
IUUC-Aca-004572	Anolis carolinensis	77.73	0.00e+00	3122.00
IUUC-Bta-012812	Bos taurus	80.59	0.00e+00	3205.00
IUUC-Cja-019191	Callithrix jacchus	80.01	0.00e+00	3167.00
IUUC-Cfa-020041	Canis familiaris	80.24	0.00e+00	2954.00
IUUC-Cre-022931	Chlamydomonas reinhardtii	33.33	2.00e-99	358.00
IUUC-Csa-023689	Chlorocebus sabaeus	79.84	0.00e+00	3097.00
IUUC-Csv-026014	Ciona savignyi	60.47	0.00e+00	2440.00
IUUC-Dno-029982	Dasypus novemcinctus	79.76	0.00e+00	3093.00
IUUC-Eca-034161	Equus caballus	79.14	0.00e+00	3054.00
IUUC-Fca-036307	Felis catus	80.59	0.00e+00	3206.00
IUUC-Fal-037332	Ficedula albicollis	79.81	0.00e+00	3141.00
IUUC-Gmo-039057	Gadus morhua	79.39	0.00e+00	3143.00
IUUC-Gac-042555	Gasterosteus aculeatus	85.61	0.00e+00	3406.00
IUUC-Ggo-045107	Gorilla gorilla	80.64	0.00e+00	3209.00
IUUC-Hsa-046482	Homo sapiens	80.64	0.00e+00	3209.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	79.17	0.00e+00	3103.00
IUUC-Loc-052642	Lepisosteus oculatus	84.59	0.00e+00	3336.00
IUUC-Laf-053649	Loxodonta africana	78.84	0.00e+00	3101.00
IUUC-Meu-056618	Macropus eugenii	69.68	0.00e+00	1597.00
IUUC-Mga-059202	Meleagris gallopavo	79.62	0.00e+00	3076.00
IUUC-Mmr-060729	Microcebus murinus	79.42	0.00e+00	3209.00
IUUC-Mdo-062462	Monodelphis domestica	80.52	0.00e+00	3111.00
IUUC-Mmu-063865	Mus musculus	79.98	0.00e+00	3207.00
IUUC-Mpu-066724	Mustela putorius furo	80.64	0.00e+00	3208.00
IUUC-Mlu-067816	Myotis lucifugus	80.49	0.00e+00	3219.00
IUUC-Opr-070213	Ochotona princeps	80.51	0.00e+00	1730.00
IUUC-Ont-071928	Oreochromis niloticus	77.63	0.00e+00	3132.00
IUUC-Oan-073563	Ornithorhynchus anatinus	80.55	0.00e+00	3191.00
IUUC-Ocu-074531	Oryctolagus cuniculus	80.33	0.00e+00	3200.00
IUUC-Ola-086943	Oryzias latipes	76.08	0.00e+00	3001.00
IUUC-Oga-088665	Otolemur garnettii	80.12	0.00e+00	3090.00
IUUC-Oar-090429	Ovis aries	80.69	0.00e+00	3211.00
IUUC-Psi-093281	Pelodiscus sinensis	79.37	0.00e+00	3168.00
IUUC-Pfo-096150	Poecilia formosa	85.96	0.00e+00	3312.00
IUUC-Rno-105002	Rattus norvegicus	79.78	0.00e+00	3209.00
IUUC-Sha-107105	Sarcophilus harrisii	78.47	0.00e+00	3006.00
IUUC-Ssc-116282	Sus scrofa	80.21	0.00e+00	3107.00
IUUC-Tgu-116807	Taeniopygia guttata	80.03	0.00e+00	3161.00
IUUC-Tru-118040	Takifugu rubripes	84.09	0.00e+00	3346.00
IUUC-Tni-120118	Tetraodon nigroviridis	81.70	0.00e+00	3326.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence