iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000027916.2	ENSXETT00000065221.1	ENSXETP00000064087.1
ENSXETG00000027916.2	ENSXETT00000058013.2	ENSXETP00000058013.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.40e-12	47.4	290	330

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 10   eprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlye 50
            prSL  LCRl+Ir+c+g+ r ++i++L+LP +Lkd+L+y+
   Q: 290  TPRSLCLLCRLCIRNCIGRSRFHLIPQLQLPTVLKDFLQYR 330
           6**************************************96 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MTVLEEKPFA QQLSNVYFTI LALFCFKLFV KISLAILSHF YIVKGNRKEA ARIAAEFYTV 60
TQGQGSWADR SPLHEAASQG RLLALKTLLS QGYNVNTLTI DHVTPRVTAA LSTSANCKGV 120

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Nucleotide Sequence
(Fasta)

GCCGCACACT GCAAATGAAA AGCTGCTCCA GGAGCAGTCT CTCGGAGTGT CGGTACTCAC 60
AGCATCACCC GGGACACATG AATGTTGACA GGAACTATCC GCTCCTTGAA CGCGGTGGTG 120

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Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR001496--SOCS_box

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50225--SOCS

Pfam

PF07525--SOCS_box

SMART

SM00248--ANK
SM00969--SOCS_box

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-010976	Astyanax mexicanus	37.61	1.00e-47	183.00
IUUC-Meu-056306	Macropus eugenii	66.67	5.00e-63	234.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence