iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069122

Ensembl Protein ID

ENSNLEP00000009727.1

UniProt Accession

G1R938; G1R938_NOMLE

Genbank Protein ID

ENSNLEP00000009727

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

ADFV01054171

Gene Name

ING1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000007977.2	ENSNLET00000010195.2	ENSNLEP00000009727.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.00e-09	36.5	211	258

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 211  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 258
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MLSPANGEQL HLVNYVEDYL DSIESLPFDL QRNVSLMREI DAKYQEILKE LDECYERFSR 60
ETDGAQKRRM LHCVQRALIR SQELGDEKIQ IVSQMVELVE NRTRQVDSHV ELLEAQQELG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGCGGACC CGGAGGCGGC AGACGGGCTC GGCAGATGTA GCCGCCGGGC CGAAGCAGGA 60
GCCGGTGGGG GGGTCGCCGG GAGAGCGAGA GCTTTGCATT TTGCAGTGCT ATTTTTTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0010941--P:regulation of cell death

KEGG

nle:100604798

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	89.96	4.00e-125	440.00
IUUC-Apl-003910	Anas platyrhynchos	89.93	5.00e-123	433.00
IUUC-Aca-004874	Anolis carolinensis	87.86	5.00e-119	420.00
IUUC-Ame-011262	Astyanax mexicanus	68.97	2.00e-96	345.00
IUUC-Bta-013507	Bos taurus	88.03	3.00e-89	321.00
IUUC-Cja-018925	Callithrix jacchus	99.28	3.00e-137	480.00
IUUC-Cfa-020947	Canis familiaris	89.61	6.00e-124	436.00
IUUC-Cpo-022286	Cavia porcellus	86.86	2.00e-95	342.00
IUUC-Cre-022920	Chlamydomonas reinhardtii	30.37	3.00e-29	121.00
IUUC-Csa-023825	Chlorocebus sabaeus	98.92	1.00e-136	478.00
IUUC-Cho-024577	Choloepus hoffmanni	88.41	8.00e-96	342.00
IUUC-Cne-027005	Cryptococcus neoformans	45.95	3.00e-16	79.30
IUUC-Dre-028562	Danio rerio	58.46	5.00e-74	270.00
IUUC-Dno-029834	Dasypus novemcinctus	90.32	4.00e-125	440.00
IUUC-Dor-030315	Dipodomys ordii	87.18	2.00e-105	375.00
IUUC-Ete-032408	Echinops telfairi	85.96	5.00e-90	324.00
IUUC-Eca-034244	Equus caballus	87.61	4.00e-97	347.00
IUUC-Fca-035391	Felis catus	85.33	6.00e-105	373.00
IUUC-Fal-036838	Ficedula albicollis	88.89	4.00e-122	430.00
IUUC-Fox-037925	Fusarium oxysporum	64.71	1.00e-19	90.90
IUUC-Gmo-038748	Gadus morhua	55.26	5.00e-77	280.00
IUUC-Gga-040619	Gallus gallus	89.25	3.00e-122	431.00
IUUC-Gac-041996	Gasterosteus aculeatus	67.02	2.00e-96	344.00
IUUC-Ggo-045481	Gorilla gorilla	98.31	7.00e-110	390.00
IUUC-Hsa-046170	Homo sapiens	98.31	7.00e-110	390.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	90.17	6.00e-99	353.00
IUUC-Lch-050397	Latimeria chalumnae	85.66	3.00e-120	424.00
IUUC-Loc-052038	Lepisosteus oculatus	77.13	6.00e-96	343.00
IUUC-Laf-054126	Loxodonta africana	91.04	6.00e-126	443.00
IUUC-Mcc-055031	Macaca mulatta	97.45	1.00e-107	382.00
IUUC-Meu-056248	Macropus eugenii	87.29	9.00e-95	339.00
IUUC-Mga-059217	Meleagris gallopavo	86.27	6.00e-93	333.00
IUUC-Mmr-061581	Microcebus murinus	89.71	2.00e-103	367.00
IUUC-Mdo-062452	Monodelphis domestica	89.61	3.00e-123	434.00
IUUC-Mmu-063412	Mus musculus	89.96	4.00e-124	437.00
IUUC-Mpu-066479	Mustela putorius furo	88.46	1.00e-97	349.00
IUUC-Mlu-067586	Myotis lucifugus	76.51	4.00e-112	397.00
IUUC-Opr-070835	Ochotona princeps	83.69	3.00e-83	300.00
IUUC-Ont-071524	Oreochromis niloticus	57.36	4.00e-78	284.00
IUUC-Oan-073023	Ornithorhynchus anatinus	88.89	1.00e-120	425.00
IUUC-Ocu-073779	Oryctolagus cuniculus	85.83	2.00e-90	324.00
IUUC-Ola-086891	Oryzias latipes	66.07	7.00e-97	346.00
IUUC-Oga-087954	Otolemur garnettii	89.96	1.00e-123	435.00
IUUC-Oar-090006	Ovis aries	89.25	7.00e-122	429.00
IUUC-Ptr-090589	Pan troglodytes	99.64	1.00e-137	481.00
IUUC-Pan-091896	Papio anubis	97.87	2.00e-108	385.00
IUUC-Psi-093266	Pelodiscus sinensis	89.96	1.00e-123	435.00
IUUC-Pma-094265	Petromyzon marinus	75.34	1.00e-33	134.00
IUUC-Pfo-096633	Poecilia formosa	57.20	5.00e-72	264.00
IUUC-Pab-098253	Pongo abelii	99.28	4.00e-137	479.00
IUUC-Pva-102753	Pteropus vampyrus	78.38	3.00e-85	308.00
IUUC-Rno-105964	Rattus norvegicus	87.61	3.00e-88	317.00
IUUC-Sha-107270	Sarcophilus harrisii	89.25	3.00e-122	431.00
IUUC-Tgu-116822	Taeniopygia guttata	89.96	2.00e-123	434.00
IUUC-Tru-118168	Takifugu rubripes	56.03	4.00e-73	267.00
IUUC-Tni-119980	Tetraodon nigroviridis	62.14	2.00e-83	302.00
IUUC-Tre-121950	Trichoderma reesei	64.29	2.00e-19	91.30
IUUC-Tvi-122341	Trichoderma virens	62.50	4.00e-16	77.00
IUUC-Ttr-128672	Tursiops truncatus	88.09	2.00e-95	342.00
IUUC-Xtr-132200	Xenopus tropicalis	82.80	5.00e-114	403.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence