iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-107270

Ensembl Protein ID

ENSSHAP00000008395.1

UniProt Accession

G3VYZ0; G3VYZ0_SARHA

Genbank Protein ID

ENSSHAP00000008395

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AEFK01128660

Gene Name

ING1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000007276.1	ENSSHAT00000008463.1	ENSSHAP00000008395.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.90e-09	36.4	211	258

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 211  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 258
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MLSPANGEQI HLVNYVEDYL DSIESLPFDL QRNVSLMREI DAKYQEILKE LDEYYEKFKR 60
ETDSVQKRRV LHCIQRALIR SQELGDEKIQ IVSQMVELVE NRTRQVDSHV ELFETCQETN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNNN AAGAGCTTTG CATTTTGCAG TGCTATTTTT TTAGGGGGGC GGGGGGTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

KEGG

shr:100922812

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	94.98	3.00e-130	457.00
IUUC-Apl-003910	Anas platyrhynchos	95.68	1.00e-131	461.00
IUUC-Aca-004874	Anolis carolinensis	94.29	5.00e-129	453.00
IUUC-Ame-011262	Astyanax mexicanus	68.62	2.00e-97	348.00
IUUC-Bta-013507	Bos taurus	88.03	2.00e-91	328.00
IUUC-Cja-018925	Callithrix jacchus	89.96	4.00e-123	433.00
IUUC-Cfa-020947	Canis familiaris	95.34	4.00e-130	457.00
IUUC-Cpo-022286	Cavia porcellus	91.10	2.00e-99	355.00
IUUC-Csa-023825	Chlorocebus sabaeus	89.61	1.00e-122	432.00
IUUC-Cho-024577	Choloepus hoffmanni	94.85	2.00e-101	360.00
IUUC-Cne-027005	Cryptococcus neoformans	45.95	3.00e-16	79.30
IUUC-Dno-029834	Dasypus novemcinctus	97.13	2.00e-132	464.00
IUUC-Dor-030315	Dipodomys ordii	88.46	3.00e-107	381.00
IUUC-Ete-032408	Echinops telfairi	92.34	3.00e-97	348.00
IUUC-Eca-034244	Equus caballus	92.74	3.00e-101	360.00
IUUC-Fca-035391	Felis catus	89.19	2.00e-109	387.00
IUUC-Fal-036838	Ficedula albicollis	94.98	4.00e-131	460.00
IUUC-Fox-037925	Fusarium oxysporum	69.57	1.00e-19	90.50
IUUC-Gga-040619	Gallus gallus	95.34	2.00e-131	461.00
IUUC-Gac-041996	Gasterosteus aculeatus	64.08	5.00e-97	347.00
IUUC-Ggo-045481	Gorilla gorilla	86.86	1.00e-95	343.00
IUUC-Hsa-046170	Homo sapiens	86.86	7.00e-96	343.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	96.15	3.00e-104	370.00
IUUC-Lch-050397	Latimeria chalumnae	91.76	8.00e-128	449.00
IUUC-Loc-052038	Lepisosteus oculatus	81.78	2.00e-102	365.00
IUUC-Laf-054126	Loxodonta africana	95.70	9.00e-131	459.00
IUUC-Mcc-055031	Macaca mulatta	87.23	3.00e-95	341.00
IUUC-Meu-056248	Macropus eugenii	96.22	5.00e-107	380.00
IUUC-Mga-059217	Meleagris gallopavo	94.42	8.00e-103	365.00
IUUC-Mmr-061581	Microcebus murinus	93.42	1.00e-106	378.00
IUUC-Mdo-062452	Monodelphis domestica	98.21	6.00e-135	473.00
IUUC-Mmu-063412	Mus musculus	92.83	8.00e-127	446.00
IUUC-Mpu-066479	Mustela putorius furo	94.02	9.00e-103	366.00
IUUC-Mlu-067586	Myotis lucifugus	81.14	2.00e-119	421.00
IUUC-Nle-069122	Nomascus leucogenys	89.25	5.00e-122	429.00
IUUC-Opr-070835	Ochotona princeps	86.27	9.00e-87	312.00
IUUC-Ont-071606	Oreochromis niloticus	60.46	1.00e-90	326.00
IUUC-Oan-073023	Ornithorhynchus anatinus	92.47	5.00e-125	440.00
IUUC-Ocu-073779	Oryctolagus cuniculus	87.50	8.00e-94	336.00
IUUC-Ola-086891	Oryzias latipes	65.71	5.00e-97	347.00
IUUC-Oga-087954	Otolemur garnettii	92.83	3.00e-127	447.00
IUUC-Oar-090006	Ovis aries	89.96	5.00e-123	433.00
IUUC-Ptr-090589	Pan troglodytes	89.61	1.00e-122	432.00
IUUC-Pan-091896	Papio anubis	87.23	2.00e-95	342.00
IUUC-Psi-093266	Pelodiscus sinensis	95.70	3.00e-132	463.00
IUUC-Pma-094265	Petromyzon marinus	75.34	7.00e-34	135.00
IUUC-Pfo-097531	Poecilia formosa	61.69	5.00e-94	337.00
IUUC-Pab-098253	Pongo abelii	89.61	2.00e-122	431.00
IUUC-Pva-102753	Pteropus vampyrus	84.17	4.00e-93	334.00
IUUC-Rno-105964	Rattus norvegicus	91.45	2.00e-91	328.00
IUUC-Tgu-116822	Taeniopygia guttata	94.98	4.00e-131	460.00
IUUC-Tru-118262	Takifugu rubripes	57.79	2.00e-79	288.00
IUUC-Tni-119980	Tetraodon nigroviridis	57.65	1.00e-84	306.00
IUUC-Tvi-122341	Trichoderma virens	62.50	3.00e-16	77.40
IUUC-Ttr-128672	Tursiops truncatus	90.64	7.00e-99	352.00
IUUC-Xtr-132200	Xenopus tropicalis	87.10	6.00e-119	419.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence