iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-097601

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01219211

Gene Name

GNB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000017424.2	ENSPPYT00000020299.2	ENSPPYP00000019528.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-40	135.7	182	220
UBD/Beta-Prp	3.80e-53	180.7	47	270

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+++v +l++ +d +++vsG+ D +ik+WD+r+  + +
   Q: 182  GHSGDVMSLSLaPDgRTFVSGACDASIKLWDVRDSMCRQ 220
           8***********99999****************988866 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee. 131
           + r+l gh a+++a+ +  d+k+lv++s+D+ + +wd  t   vh++   ++ v+++++ psg++++ G+ d++  ++ l+t++     
   Q: 47   TRRTLHGHLAKIYAMHWGTDSKLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRv 135
           5689*****************************************************************************99877666 PP
   S: 132  ..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
              l gh+g  +c ++ + +n ++++s D+t+ lWd++tg+    + g h ++v sls+ ++g+ +vsg++d ++klwd++ + c +t+
   Q: 136  srELPGHTGYLSCCRFLD-DNQIITSSGDTTCALWDIETGQQTVGFAG-HSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF 222
           779*************99.7778999********************99.**************************************** PP
   S: 219  nghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvi 268
           +gh++ ++ v+f+pn+  + +gs+D + r++dlr ++ l ++++ n  +i
   Q: 223  IGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN--II 270
           ***************************************9999854..55 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MSELEQLRQE AEQLRNQIRD ARKACGDSTL TQIPAGLDPV GRIQMRTRRT LHGHLAKIYA 60
MHWGTDSKLL VSASQDGKLI IWDSYTTNKV HAIPLRSSWV MTCAYAPSGN FVACGGLDNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCTCGGGCC AGCGGCCAGG AGCTGCCTCC CCCAGCCCCC GTCCCGCGGC CCCCAGCCGC 60
CCCCAACCCC GCCCCACGGG CCCGGCGCCA TGAGTGAGCT GGAGCAACTG AGACAGGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0005925--C:focal adhesion
GO:0005765--C:lysosomal membrane
GO:0043209--C:myelin sheath
GO:0048471--C:perinuclear region of cytoplasm
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001395	Ailuropoda melanoleuca	98.14	0.00e+00	653.00
IUUC-Ame-011124	Astyanax mexicanus	93.24	0.00e+00	632.00
IUUC-Bta-013430	Bos taurus	99.07	0.00e+00	660.00
IUUC-Cel-018704	Caenorhabditis elegans	84.71	1.00e-178	618.00
IUUC-Cja-019794	Callithrix jacchus	99.07	0.00e+00	660.00
IUUC-Cfa-020395	Canis familiaris	88.54	1.00e-174	605.00
IUUC-Cpo-021865	Cavia porcellus	99.07	0.00e+00	659.00
IUUC-Csa-023572	Chlorocebus sabaeus	99.07	0.00e+00	660.00
IUUC-Cho-024766	Choloepus hoffmanni	88.00	3.00e-175	607.00
IUUC-Cin-025309	Ciona intestinalis	79.59	2.00e-168	584.00
IUUC-Csv-026258	Ciona savignyi	79.88	1.00e-168	585.00
IUUC-Cgl-026673	Colletotrichum gloeosporioides	65.20	4.00e-135	474.00
IUUC-Dre-027957	Danio rerio	93.50	0.00e+00	629.00
IUUC-Dno-029001	Dasypus novemcinctus	99.07	0.00e+00	659.00
IUUC-Dor-030322	Dipodomys ordii	87.93	6.00e-165	573.00
IUUC-Dme-031748	Drosophila melanogaster	80.88	2.00e-171	594.00
IUUC-Ete-032710	Echinops telfairi	87.66	4.00e-165	573.00
IUUC-Eca-034149	Equus caballus	99.07	0.00e+00	660.00
IUUC-Eeu-034978	Erinaceus europaeus	86.81	1.00e-142	499.00
IUUC-Fca-036537	Felis catus	99.07	0.00e+00	660.00
IUUC-Fox-037946	Fusarium oxysporum	65.50	3.00e-130	457.00
IUUC-Fso-038136	Fusarium solani	65.50	3.00e-130	457.00
IUUC-Gmo-039332	Gadus morhua	93.81	0.00e+00	629.00
IUUC-Ggr-039969	Gaeumannomyces graminis	64.91	6.00e-134	470.00
IUUC-Gac-041932	Gasterosteus aculeatus	92.88	0.00e+00	625.00
IUUC-Ggo-044543	Gorilla gorilla	99.07	0.00e+00	660.00
IUUC-Hsa-046432	Homo sapiens	99.07	0.00e+00	660.00
IUUC-Itr-048049	Ictidomys tridecemlineatus	99.10	0.00e+00	681.00
IUUC-Kpa-049192	Komagataella pastoris	38.06	2.00e-62	233.00
IUUC-Laf-053865	Loxodonta africana	99.07	0.00e+00	659.00
IUUC-Mcc-055781	Macaca mulatta	99.34	0.00e+00	628.00
IUUC-Meu-056902	Macropus eugenii	98.45	0.00e+00	657.00
IUUC-Mor-057188	Magnaporthe oryzae	64.62	3.00e-133	467.00
IUUC-Mpo-057544	Magnaporthe poae	64.62	4.00e-134	471.00
IUUC-Mtr-058752	Medicago truncatula	44.94	2.00e-85	308.00
IUUC-Mmr-061015	Microcebus murinus	99.07	0.00e+00	660.00
IUUC-Mdo-062734	Monodelphis domestica	98.45	0.00e+00	657.00
IUUC-Mmu-063737	Mus musculus	99.07	0.00e+00	659.00
IUUC-Mpu-066784	Mustela putorius furo	98.71	0.00e+00	632.00
IUUC-Mlu-067912	Myotis lucifugus	98.76	0.00e+00	658.00
IUUC-Nle-069612	Nomascus leucogenys	88.54	9.00e-175	605.00
IUUC-Opr-070866	Ochotona princeps	99.07	0.00e+00	660.00
IUUC-Ont-072526	Oreochromis niloticus	92.57	3.00e-180	623.00
IUUC-Ocu-074344	Oryctolagus cuniculus	99.07	0.00e+00	660.00
IUUC-Ola-087468	Oryzias latipes	90.09	5.00e-177	613.00
IUUC-Oga-089046	Otolemur garnettii	99.07	0.00e+00	660.00
IUUC-Oar-089822	Ovis aries	92.57	2.00e-175	607.00
IUUC-Ptr-091444	Pan troglodytes	99.07	0.00e+00	660.00
IUUC-Pan-092045	Papio anubis	99.07	0.00e+00	660.00
IUUC-Pma-094748	Petromyzon marinus	90.87	4.00e-139	486.00
IUUC-Pca-100940	Procavia capensis	99.07	0.00e+00	660.00
IUUC-Pva-102229	Pteropus vampyrus	98.76	0.00e+00	653.00
IUUC-Rno-106104	Rattus norvegicus	99.07	0.00e+00	660.00
IUUC-Sha-107632	Sarcophilus harrisii	98.45	0.00e+00	657.00
IUUC-Sja-107891	Schizosaccharomyces japonicus	35.57	1.00e-57	216.00
IUUC-Sar-113642	Sorex araneus	91.54	2.00e-150	525.00
IUUC-Ssc-115595	Sus scrofa	99.07	0.00e+00	660.00
IUUC-Tru-118401	Takifugu rubripes	92.26	4.00e-180	623.00
IUUC-Tsy-119354	Tarsius syrichta	86.69	2.00e-172	597.00
IUUC-Tni-120216	Tetraodon nigroviridis	91.95	8.00e-180	622.00
IUUC-Tre-122156	Trichoderma reesei	65.20	2.00e-134	471.00
IUUC-Tvi-122640	Trichoderma virens	65.20	2.00e-134	471.00
IUUC-Tbe-128132	Tupaia belangeri	99.22	4.00e-148	516.00
IUUC-Ttr-128403	Tursiops truncatus	99.07	0.00e+00	660.00
IUUC-Vda-129855	Verticillium dahliae	69.84	3.00e-128	451.00
IUUC-Vpa-130474	Vicugna pacos	97.79	3.00e-76	278.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence