iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054323

Ensembl Protein ID

ENSLAFP00000011195.3

UniProt Accession

G3TB71; G3TB71_LOXAF

Protein Name

Uncharacterized protein

Gene Name

PPARA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000013377.3	ENSLAFT00000013377.3	ENSLAFP00000011195.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	95.09	0.00e+00	890.00	IUUC-Hsa-046893

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MMDMESPICP LTPLEADDLE SPLSEEFLQE MGNIQEISQS IGEDSSGSFS FTDYQYVGSG 60
PGSDGSVITD TLSPASSPSS VNYPVVPGST DETSSRALNI ECRICGDKAS GYHYGVHACE 120

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Nucleotide Sequence
(Fasta)

ATGATGGACA TGGAAAGCCC TATTTGTCCC CTGACCCCGC TCGAGGCTGA CGACCTGGAA 60
AGCCCACTGT CTGAAGAATT CCTACAGGAA ATGGGAAATA TTCAAGAGAT TTCCCAGTCC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003076--1Cnucl_rcpt_A
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01289--PROXISOMPAAR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008144--F:drug binding
GO:0008289--F:lipid binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0070166--P:enamel mineralization
GO:0008544--P:epidermis development
GO:0006631--P:fatty acid metabolic process
GO:0032099--P:negative regulation of appetite
GO:0010887--P:negative regulation of cholesterol storage
GO:0050728--P:negative regulation of inflammatory response
GO:1903038--P:negative regulation of leukocyte cell-cell adhesion
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:1902894--P:negative regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0046321--P:positive regulation of fatty acid oxidation
GO:0045722--P:positive regulation of gluconeogenesis
GO:0072366--P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0042752--P:regulation of circadian rhythm
GO:0072363--P:regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072369--P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
GO:0042060--P:wound healing

KEGG

lav:100657770

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002222	Ailuropoda melanoleuca	93.40	0.00e+00	918.00
IUUC-Apl-003330	Anas platyrhynchos	87.50	0.00e+00	837.00
IUUC-Aca-004598	Anolis carolinensis	86.11	0.00e+00	828.00
IUUC-Acl-008339	Aspergillus clavatus	45.45	1.30e-01	29.60
IUUC-Ame-011508	Astyanax mexicanus	72.55	0.00e+00	692.00
IUUC-Bta-012621	Bos taurus	94.66	0.00e+00	889.00
IUUC-Cja-019688	Callithrix jacchus	95.30	0.00e+00	897.00
IUUC-Cfa-020859	Canis familiaris	94.23	0.00e+00	921.00
IUUC-Cpo-021607	Cavia porcellus	87.82	0.00e+00	830.00
IUUC-Csa-023313	Chlorocebus sabaeus	94.44	0.00e+00	880.00
IUUC-Cho-024741	Choloepus hoffmanni	83.12	0.00e+00	748.00
IUUC-Dre-027446	Danio rerio	72.13	0.00e+00	683.00
IUUC-Dno-029173	Dasypus novemcinctus	91.67	0.00e+00	861.00
IUUC-Dor-030581	Dipodomys ordii	89.94	0.00e+00	807.00
IUUC-Dme-031794	Drosophila melanogaster	34.47	1.00e-55	212.00
IUUC-Ete-032330	Echinops telfairi	92.09	0.00e+00	894.00
IUUC-Eca-033712	Equus caballus	95.09	0.00e+00	880.00
IUUC-Fca-036555	Felis catus	94.89	0.00e+00	924.00
IUUC-Fal-036677	Ficedula albicollis	87.18	0.00e+00	833.00
IUUC-Gmo-039240	Gadus morhua	81.02	0.00e+00	637.00
IUUC-Gga-040473	Gallus gallus	88.03	0.00e+00	839.00
IUUC-Gac-041872	Gasterosteus aculeatus	71.88	0.00e+00	704.00
IUUC-Ggo-045226	Gorilla gorilla	95.09	0.00e+00	889.00
IUUC-Hsa-046893	Homo sapiens	95.09	0.00e+00	889.00
IUUC-Itr-048952	Ictidomys tridecemlineatus	91.45	0.00e+00	861.00
IUUC-Lch-050116	Latimeria chalumnae	79.27	0.00e+00	765.00
IUUC-Loc-052131	Lepisosteus oculatus	83.00	0.00e+00	684.00
IUUC-Mcc-054841	Macaca mulatta	95.09	0.00e+00	886.00
IUUC-Meu-056833	Macropus eugenii	81.84	0.00e+00	746.00
IUUC-Mga-059995	Meleagris gallopavo	79.03	0.00e+00	743.00
IUUC-Mdo-061954	Monodelphis domestica	88.17	0.00e+00	784.00
IUUC-Mmu-064295	Mus musculus	91.03	0.00e+00	829.00
IUUC-Mpu-066216	Mustela putorius furo	94.44	0.00e+00	922.00
IUUC-Nle-069970	Nomascus leucogenys	94.87	0.00e+00	886.00
IUUC-Ont-071594	Oreochromis niloticus	72.94	0.00e+00	695.00
IUUC-Oan-073501	Ornithorhynchus anatinus	91.20	0.00e+00	769.00
IUUC-Ocu-074634	Oryctolagus cuniculus	83.30	0.00e+00	821.00
IUUC-Oni-082926	Oryza nivara	29.41	1.20e-02	30.80
IUUC-Ola-086585	Oryzias latipes	78.84	0.00e+00	630.00
IUUC-Oga-088738	Otolemur garnettii	95.30	0.00e+00	880.00
IUUC-Oar-090453	Ovis aries	94.23	0.00e+00	888.00
IUUC-Ptr-091518	Pan troglodytes	94.87	0.00e+00	882.00
IUUC-Pan-092006	Papio anubis	94.87	0.00e+00	882.00
IUUC-Psi-093352	Pelodiscus sinensis	86.23	0.00e+00	837.00
IUUC-Pfo-096060	Poecilia formosa	71.25	0.00e+00	680.00
IUUC-Pab-098602	Pongo abelii	88.61	0.00e+00	789.00
IUUC-Pva-102175	Pteropus vampyrus	88.46	0.00e+00	858.00
IUUC-Rno-105283	Rattus norvegicus	91.24	0.00e+00	829.00
IUUC-Sce-106436	Saccharomyces cerevisiae	29.03	8.00e-03	32.00
IUUC-Sha-106560	Sarcophilus harrisii	91.88	0.00e+00	867.00
IUUC-Smo-109075	Selaginella moellendorffii	30.00	1.00e-01	29.60
IUUC-Ssc-115266	Sus scrofa	94.66	0.00e+00	930.00
IUUC-Tgu-116778	Taeniopygia guttata	87.18	0.00e+00	833.00
IUUC-Tru-118436	Takifugu rubripes	71.88	0.00e+00	695.00
IUUC-Tsy-119642	Tarsius syrichta	97.84	6.00e-133	467.00
IUUC-Tni-119859	Tetraodon nigroviridis	71.88	0.00e+00	690.00
IUUC-Tbe-127464	Tupaia belangeri	92.52	0.00e+00	903.00
IUUC-Ttr-129307	Tursiops truncatus	90.83	0.00e+00	836.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence