iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000014074.2	ENSCJAT00000060318.1	ENSCJAP00000049785.1
ENSCJAG00000014074.2	ENSCJAT00000052843.1	ENSCJAP00000048418.1
ENSCJAG00000014074.2	ENSCJAT00000027398.1	ENSCJAP00000025927.1
ENSCJAG00000014074.2	ENSCJAT00000027421.1	ENSCJAP00000025948.1
ENSCJAG00000014074.2	ENSCJAT00000060375.1	ENSCJAP00000048306.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.70e-79	267.3	42	482

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           G++N+g tCY+NS+LQ+L+++pe+re+l++  +e+l   ++k++       +  +lq+lf++l+  +++a s+++l+++++++++e  +
   Q: 42   GIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGLFEDKDKPDakirIIPLQLQRLFAQLLLLDQEAASTTDLTDSFGWTSNE--E 128
           9*****************************888888765543333245557889******************************98..* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           ++q+D+qE+ ++l+++le++l                            +++++li++l++g++ +qi+c+ec+nvs+r+e+fldl+++
   Q: 129  MRQHDVQELNRILFSALETSL--------------------------VGTSGHDLINRLYHGTIVNQIVCKECKNVSERQEDFLDLTVA 191
           *********************..........................789*************************************** PP
   S: 176  vpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           v++ +      l+d+L +++++ee ++++n y+c +c+++++a k+ kl+klP++L++ L Rf+f+  ++ r k +++++fpl+++l+p
   Q: 192  VKNVS-----GLEDALwNMYVEEEVFDCDNLYHCGTCDRLVKAAKSAKLRKLPPFLTVSLLRFNFDFVKCERYKETSCYTFPLRINLKP 275
           *****.....9****************************************************************************** PP
   S: 264  fctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................... 301
           fc+++e ++  +++Y+L++v++H+G++ +GHY++y+k+                                                   
   Q: 276  FCEQSELDDL-EYTYDLFSVIIHKGGCYGGHYHVYIKDvdhlgnwqfqeekskpdvnlkdpqneeeidhplmilkaillqeennlipvd 363
           ****999987.9***************************************************************************** PP
   S: 302  ..............................................................................ekgk.....Wl 307
                                                                                         +  +     W+
   Q: 364  qlgqkllkkigiswnkkyrkqhgplrkflqlhsqifllssdestvrllkngslqaetdfqsndqqifktpppespglnN--SiscphWF 450
           *******************************************************999999999999998888887651..234567** PP
   S: 308  lfdDskVtevkeeevleetg..staYvlfYkr 337
            ++DskV++++e++++++ +  ++aY+lfY++
   Q: 451  DINDSKVQPIREKDIEQQFQgkESAYMLFYRK 482
           *****************9889*********98 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MFGNLFEEDY STVSNNQYGK GKKLKTKVLE PPAPREFTNL SGIRNQGGTC YLNSLLQTLH 60
FTPEFREALF SLGPEELGLF EDKDKPDAKI RIIPLQLQRL FAQLLLLDQE AASTTDLTDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTTCCGGA GACCCGCCCT CGCCAACATG GCGGCGCCCC ACAGGGGCGG GTTCGTTCGC 60
TTCGCTTTTT GGCCAAGGCG GGGGTCTGGG CTTCAGGCAG TAAGTTGGGC AGGCGGCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	84.53	0.00e+00	1951.00
IUUC-Apl-004105	Anas platyrhynchos	64.47	0.00e+00	1556.00
IUUC-Aca-004715	Anolis carolinensis	62.49	0.00e+00	1480.00
IUUC-Ame-011073	Astyanax mexicanus	46.88	0.00e+00	1015.00
IUUC-Bta-012487	Bos taurus	83.02	0.00e+00	2005.00
IUUC-Cfa-020645	Canis familiaris	79.33	0.00e+00	1257.00
IUUC-Cpo-022160	Cavia porcellus	79.90	0.00e+00	1949.00
IUUC-Csa-023078	Chlorocebus sabaeus	93.13	0.00e+00	2325.00
IUUC-Cho-025013	Choloepus hoffmanni	66.46	0.00e+00	832.00
IUUC-Csv-026193	Ciona savignyi	56.17	2.00e-59	221.00
IUUC-Dre-027416	Danio rerio	48.91	0.00e+00	1137.00
IUUC-Dno-029639	Dasypus novemcinctus	80.94	0.00e+00	1686.00
IUUC-Dor-030624	Dipodomys ordii	91.03	7.00e-154	538.00
IUUC-Ete-032626	Echinops telfairi	63.96	0.00e+00	750.00
IUUC-Eca-034208	Equus caballus	85.29	0.00e+00	2101.00
IUUC-Eeu-035340	Erinaceus europaeus	46.36	6.00e-94	339.00
IUUC-Fca-035886	Felis catus	73.55	0.00e+00	767.00
IUUC-Fal-036925	Ficedula albicollis	64.11	0.00e+00	1447.00
IUUC-Gmo-038597	Gadus morhua	46.00	0.00e+00	899.00
IUUC-Gga-041171	Gallus gallus	64.25	0.00e+00	1543.00
IUUC-Gac-041362	Gasterosteus aculeatus	46.06	0.00e+00	957.00
IUUC-Ggo-045069	Gorilla gorilla	93.52	0.00e+00	2137.00
IUUC-Hsa-046715	Homo sapiens	94.50	0.00e+00	2329.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	82.11	0.00e+00	1979.00
IUUC-Lch-050182	Latimeria chalumnae	52.33	0.00e+00	1152.00
IUUC-Loc-052705	Lepisosteus oculatus	54.31	0.00e+00	1271.00
IUUC-Laf-054132	Loxodonta africana	81.74	0.00e+00	2028.00
IUUC-Mcc-055734	Macaca mulatta	93.37	0.00e+00	2322.00
IUUC-Meu-056135	Macropus eugenii	86.27	1.00e-114	407.00
IUUC-Mga-060092	Meleagris gallopavo	63.72	0.00e+00	1511.00
IUUC-Mmr-061546	Microcebus murinus	84.44	0.00e+00	2047.00
IUUC-Mdo-061935	Monodelphis domestica	61.72	0.00e+00	1488.00
IUUC-Mmu-063630	Mus musculus	80.05	0.00e+00	1974.00
IUUC-Mpu-066579	Mustela putorius furo	80.86	0.00e+00	2012.00
IUUC-Mlu-068034	Myotis lucifugus	83.76	0.00e+00	1988.00
IUUC-Nle-069082	Nomascus leucogenys	93.13	0.00e+00	1944.00
IUUC-Opr-070953	Ochotona princeps	71.51	0.00e+00	974.00
IUUC-Ont-072435	Oreochromis niloticus	47.55	0.00e+00	1088.00
IUUC-Oan-073339	Ornithorhynchus anatinus	67.09	0.00e+00	1565.00
IUUC-Ocu-073760	Oryctolagus cuniculus	81.81	0.00e+00	2016.00
IUUC-Ola-087015	Oryzias latipes	46.93	0.00e+00	917.00
IUUC-Oga-088960	Otolemur garnettii	86.35	0.00e+00	2110.00
IUUC-Oar-089853	Ovis aries	83.62	0.00e+00	2039.00
IUUC-Ptr-091093	Pan troglodytes	94.58	0.00e+00	2333.00
IUUC-Pan-091962	Papio anubis	92.64	0.00e+00	2314.00
IUUC-Psi-093691	Pelodiscus sinensis	65.73	0.00e+00	1597.00
IUUC-Pma-094428	Petromyzon marinus	64.39	7.00e-91	327.00
IUUC-Pfo-096983	Poecilia formosa	47.94	0.00e+00	1020.00
IUUC-Pab-097860	Pongo abelii	94.35	0.00e+00	2174.00
IUUC-Pca-100514	Procavia capensis	79.10	0.00e+00	650.00
IUUC-Pva-102771	Pteropus vampyrus	83.48	0.00e+00	1898.00
IUUC-Rno-105405	Rattus norvegicus	79.24	0.00e+00	1925.00
IUUC-Sha-107376	Sarcophilus harrisii	64.02	0.00e+00	1467.00
IUUC-Ssc-115819	Sus scrofa	78.86	0.00e+00	1384.00
IUUC-Tgu-117262	Taeniopygia guttata	63.04	0.00e+00	1525.00
IUUC-Tru-117601	Takifugu rubripes	48.58	0.00e+00	1108.00
IUUC-Tsy-118996	Tarsius syrichta	76.56	0.00e+00	1670.00
IUUC-Tni-120682	Tetraodon nigroviridis	43.17	0.00e+00	872.00
IUUC-Tbe-127616	Tupaia belangeri	67.06	0.00e+00	1159.00
IUUC-Ttr-129075	Tursiops truncatus	80.84	0.00e+00	1870.00
IUUC-Vpa-130108	Vicugna pacos	83.38	0.00e+00	1808.00
IUUC-Xtr-132623	Xenopus tropicalis	52.67	0.00e+00	1183.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence