iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000005836.4	ENSCAFT00000009423.4	ENSCAFP00000008746.3
ENSCAFG00000005836.4	ENSCAFT00000046269.1	ENSCAFP00000037011.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.60e-07	32.0	226	276

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..........kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C + +          ++ ++ l+C+Hvfh+ C+  w    +   k+++CP+C+
   Q: 226  CAVCGQQIfvdvseegiiEN-TYRLSCNHVFHEFCIRGW----CIVGKKQTCPYCK 276
           9***9888888887777655.777***************....889999******7 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MQYTVSHRLE TKWLENREIV QVDMSDLSPE EQWRVEHARM HAKHRGHEAM HAEMVLILIA 60
TLVVAQLLLV QWKQRHPRSY NMVTLFQMWV VPLYFTVKLH WWRFLVIWIF FSAVTAFVTF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTGAGCGG CGGAAGCAGC TGGCTAGCGG GGGGACGAAG GGAGGGGGAG AGTTGTGAAG 60
ATGGCGGCAG TGGTGGAGGT GGAGGTTGGA GGAGGTGCTG CCGGGGAACG GGAGCTAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002350	Ailuropoda melanoleuca	98.05	7.00e-172	596.00
IUUC-Apl-003882	Anas platyrhynchos	87.16	2.00e-142	498.00
IUUC-Aca-004343	Anolis carolinensis	89.13	2.00e-22	96.70
IUUC-Aly-005550	Arabidopsis lyrata	37.10	3.00e-06	47.00
IUUC-Ame-010680	Astyanax mexicanus	86.58	3.00e-157	547.00
IUUC-Bta-013045	Bos taurus	98.98	8.00e-165	572.00
IUUC-Bci-013624	Botrytis cinerea	36.36	8.00e-07	48.90
IUUC-Cel-018296	Caenorhabditis elegans	51.42	1.00e-97	349.00
IUUC-Cja-019866	Callithrix jacchus	98.38	2.00e-172	598.00
IUUC-Cpo-022268	Cavia porcellus	97.73	3.00e-170	590.00
IUUC-Cre-022649	Chlamydomonas reinhardtii	41.83	2.00e-54	205.00
IUUC-Csa-023727	Chlorocebus sabaeus	99.03	5.00e-173	599.00
IUUC-Cho-025016	Choloepus hoffmanni	98.08	9.00e-174	602.00
IUUC-Cin-025281	Ciona intestinalis	64.36	7.00e-124	436.00
IUUC-Csv-026338	Ciona savignyi	63.76	8.00e-112	396.00
IUUC-Dre-027836	Danio rerio	82.14	1.00e-141	495.00
IUUC-Dno-029737	Dasypus novemcinctus	97.43	3.00e-172	597.00
IUUC-Dor-031070	Dipodomys ordii	91.18	2.00e-153	535.00
IUUC-Dme-031867	Drosophila melanogaster	59.80	1.00e-111	395.00
IUUC-Ete-032964	Echinops telfairi	88.46	1.00e-162	565.00
IUUC-Eca-034398	Equus caballus	98.70	2.00e-172	598.00
IUUC-Eeu-035318	Erinaceus europaeus	64.40	3.00e-115	407.00
IUUC-Fca-035807	Felis catus	99.35	2.00e-175	607.00
IUUC-Fal-036721	Ficedula albicollis	95.50	5.00e-157	546.00
IUUC-Gmo-039699	Gadus morhua	88.64	2.00e-148	518.00
IUUC-Gga-040840	Gallus gallus	95.92	8.00e-160	555.00
IUUC-Gac-042639	Gasterosteus aculeatus	85.62	3.00e-146	510.00
IUUC-Ggo-045576	Gorilla gorilla	99.02	7.00e-172	595.00
IUUC-Hsa-046468	Homo sapiens	98.70	1.00e-172	598.00
IUUC-Itr-048638	Ictidomys tridecemlineatus	98.79	3.00e-145	507.00
IUUC-Lch-050207	Latimeria chalumnae	82.47	3.00e-145	507.00
IUUC-Loc-052172	Lepisosteus oculatus	89.61	2.00e-159	554.00
IUUC-Laf-053879	Loxodonta africana	97.12	2.00e-173	600.00
IUUC-Mcc-055492	Macaca mulatta	99.03	5.00e-173	599.00
IUUC-Meu-055976	Macropus eugenii	82.08	2.00e-136	478.00
IUUC-Mga-059989	Meleagris gallopavo	95.19	2.00e-170	591.00
IUUC-Mmr-060894	Microcebus murinus	99.03	5.00e-173	599.00
IUUC-Mdo-061826	Monodelphis domestica	95.10	2.00e-164	571.00
IUUC-Mmu-063717	Mus musculus	98.70	1.00e-172	598.00
IUUC-Mpu-066826	Mustela putorius furo	98.70	7.00e-173	599.00
IUUC-Mlu-068081	Myotis lucifugus	96.19	1.00e-170	592.00
IUUC-Nle-069734	Nomascus leucogenys	99.03	5.00e-173	599.00
IUUC-Opr-070379	Ochotona princeps	95.19	5.00e-166	576.00
IUUC-Ont-071855	Oreochromis niloticus	86.17	3.00e-146	510.00
IUUC-Ocu-074363	Oryctolagus cuniculus	98.40	4.00e-174	603.00
IUUC-Ola-086489	Oryzias latipes	84.03	2.00e-144	504.00
IUUC-Oga-088323	Otolemur garnettii	99.67	1.00e-174	605.00
IUUC-Oar-090243	Ovis aries	97.12	1.00e-172	598.00
IUUC-Ptr-091374	Pan troglodytes	98.70	1.00e-172	598.00
IUUC-Pan-092115	Papio anubis	99.03	5.00e-173	599.00
IUUC-Psi-093658	Pelodiscus sinensis	96.03	1.00e-152	532.00
IUUC-Pfo-097261	Poecilia formosa	84.39	6.00e-145	506.00
IUUC-Pab-098579	Pongo abelii	98.70	1.00e-172	598.00
IUUC-Pop-099603	Populus trichocarpa	26.02	5.00e-07	49.30
IUUC-Pca-100119	Procavia capensis	92.31	7.00e-158	549.00
IUUC-Pva-102111	Pteropus vampyrus	98.70	3.00e-171	593.00
IUUC-Rno-105364	Rattus norvegicus	98.40	5.00e-174	603.00
IUUC-Sha-107005	Sarcophilus harrisii	94.55	9.00e-170	588.00
IUUC-Sar-113163	Sorex araneus	98.70	7.00e-173	599.00
IUUC-Ssc-115633	Sus scrofa	96.18	5.00e-174	603.00
IUUC-Tgu-116869	Taeniopygia guttata	96.95	4.00e-162	563.00
IUUC-Tru-118217	Takifugu rubripes	84.23	1.00e-153	535.00
IUUC-Tsy-119308	Tarsius syrichta	99.03	3.00e-173	600.00
IUUC-Tni-119882	Tetraodon nigroviridis	84.91	4.00e-154	537.00
IUUC-Tbe-127912	Tupaia belangeri	71.26	4.00e-107	380.00
IUUC-Ttr-129087	Tursiops truncatus	99.02	2.00e-172	598.00
IUUC-Vpa-130785	Vicugna pacos	96.60	1.00e-159	555.00
IUUC-Xtr-132801	Xenopus tropicalis	92.81	6.00e-155	540.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence