iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004436

UUCD1 version

UUC-AnC-01020

Ensembl Protein ID

ENSACAP00000017377.3

UniProt Accession

G1KU89; G1KU89_ANOCA

Protein Name

Uncharacterized protein

Gene Name

USP43

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000017652.3	ENSACAT00000017718.3	ENSACAP00000017377.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.50e-62	209.0	34	524

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 130  aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke................................. 185
           +   +++k++s++++ Fq q++s+++c++c ++s++++pfl +slp+p ++++ ++                                 
   Q: 34   QAAAQPSKGQSFVQNHFQAQYRSSLTCPHCLKQSNTFDPFLCISLPIPLRQTRPLNvtlvfqsksqrfvrvgltvplfstvaklremva 122
           66788999******************************************9775559******************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 123  eegklspdqvilaelgpsgfqcsfsddedlntiadgdsiyafqaplsfskasssrlsgcpqslpsspnvsdpegqrlvhngaissdylh 211
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 212  hgvggrilllvcnvagtgqqavrfgppllmredramswdqlqqcilgkmrylmrreaqvqatgnlfqvrvlggstlcsylspqdswply 300
           ***************************************************************************************** PP
   S: 186  .............................................................slqdcLesftkeeelegenkyycekckk 213
                                                                        +l++c++ +tkee+l  ++++ c++c+ 
   Q: 301  hpavdrvlqfsgpggpahvklviewdvstkeslfgniqeevvedaesvrmkqqlhlqqhscTLDECFQLYTKEEQLAPDDAWRCPHCQV 389
           ***************************************************************************************** PP
   S: 214  kqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts..............peekqke....kkkYeLiav 283
           +q+   kl+l++lP++Li+hLkRf  ++ +++r+k+++ v fpl  Ld++p++++              p     e    +  Y+L+av
   Q: 390  LQQGMVKLSLWTLPDILIIHLKRF--RQVGEQRHKLSTLVRFPLYgLDMAPHVAKrsrgskwgpwkqptP-----EsnqcNFLYDLYAV 471
           ************************..99999************************555555555555443.....055559******** PP
   S: 284  vvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           ++H+Gs+++GHY+ay++n  +g+W+ +dDs+V++v e+ev +   + aY+lfY+rr
   Q: 472  CNHHGSMQGGHYTAYCRNaLDGHWYSYDDSTVEAVLEDEVST---RGAYILFYQRR 524
           ******************55666*******************...*********96 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MHEDLCSVSL NQKVKVSGKP LLGQEESSSG GGAQAAAQPS KGQSFVQNHF QAQYRSSLTC 60
PHCLKQSNTF DPFLCISLPI PLRQTRPLNV TLVFQSKSQR FVRVGLTVPL FSTVAKLREM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCAGCAAC GGCTCATTTC TTATTTCGTG CACAGTTACT AACATCACCC TTTCTTTTAA 60
CTGCAGAATG TCGTCTCCAA GTATGGTGCA CAGTTCCGTG GAAATTCGCA ACATGATGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	50.27	0.00e+00	772.00
IUUC-Ame-011153	Astyanax mexicanus	52.86	0.00e+00	831.00
IUUC-Bta-013560	Bos taurus	53.35	0.00e+00	837.00
IUUC-Cja-018737	Callithrix jacchus	53.97	0.00e+00	825.00
IUUC-Cfa-020347	Canis familiaris	50.11	0.00e+00	766.00
IUUC-Csa-023656	Chlorocebus sabaeus	54.26	0.00e+00	819.00
IUUC-Dre-028066	Danio rerio	53.09	0.00e+00	891.00
IUUC-Dno-028855	Dasypus novemcinctus	51.71	0.00e+00	721.00
IUUC-Dor-030475	Dipodomys ordii	65.59	5.00e-151	528.00
IUUC-Dme-032088	Drosophila melanogaster	34.54	2.00e-77	284.00
IUUC-Eca-034147	Equus caballus	61.62	0.00e+00	780.00
IUUC-Fca-036550	Felis catus	50.48	0.00e+00	750.00
IUUC-Gmo-038903	Gadus morhua	56.09	1.00e-169	590.00
IUUC-Gac-042087	Gasterosteus aculeatus	51.62	0.00e+00	761.00
IUUC-Ggo-045171	Gorilla gorilla	54.05	0.00e+00	824.00
IUUC-Hsa-045961	Homo sapiens	54.10	0.00e+00	825.00
IUUC-Loc-052852	Lepisosteus oculatus	69.81	0.00e+00	827.00
IUUC-Laf-054033	Loxodonta africana	50.92	0.00e+00	772.00
IUUC-Mcc-055431	Macaca mulatta	54.32	0.00e+00	824.00
IUUC-Mmr-061035	Microcebus murinus	53.65	0.00e+00	794.00
IUUC-Mdo-062172	Monodelphis domestica	63.25	0.00e+00	745.00
IUUC-Mmu-063966	Mus musculus	51.86	0.00e+00	803.00
IUUC-Mpu-066307	Mustela putorius furo	52.08	0.00e+00	770.00
IUUC-Nle-070172	Nomascus leucogenys	54.48	0.00e+00	821.00
IUUC-Opr-070499	Ochotona princeps	67.14	0.00e+00	660.00
IUUC-Ont-071920	Oreochromis niloticus	52.46	0.00e+00	840.00
IUUC-Ocu-074014	Oryctolagus cuniculus	64.85	0.00e+00	776.00
IUUC-Ola-086360	Oryzias latipes	53.22	0.00e+00	796.00
IUUC-Oga-088202	Otolemur garnettii	51.30	0.00e+00	786.00
IUUC-Oar-089819	Ovis aries	52.85	0.00e+00	837.00
IUUC-Ptr-091076	Pan troglodytes	54.54	0.00e+00	827.00
IUUC-Pan-092248	Papio anubis	54.05	0.00e+00	819.00
IUUC-Pfo-096332	Poecilia formosa	59.39	0.00e+00	752.00
IUUC-Pab-098453	Pongo abelii	54.15	0.00e+00	823.00
IUUC-Pca-100290	Procavia capensis	44.13	8.00e-101	361.00
IUUC-Pva-102317	Pteropus vampyrus	45.82	0.00e+00	629.00
IUUC-Rno-104948	Rattus norvegicus	50.68	0.00e+00	766.00
IUUC-Sha-106558	Sarcophilus harrisii	49.59	0.00e+00	812.00
IUUC-Sar-113105	Sorex araneus	51.52	2.00e-180	625.00
IUUC-Ssc-115312	Sus scrofa	51.66	0.00e+00	803.00
IUUC-Tru-117995	Takifugu rubripes	53.39	0.00e+00	815.00
IUUC-Tni-120517	Tetraodon nigroviridis	59.66	0.00e+00	693.00
IUUC-Tbe-127439	Tupaia belangeri	38.72	5.00e-51	196.00
IUUC-Ttr-128829	Tursiops truncatus	46.07	0.00e+00	654.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence