iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-070172

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01082909

Gene Name

USP43

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000010074.1	ENSNLET00000012900.1	ENSNLEP00000012301.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.60e-92	308.7	101	710

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+gNtC+mN+v+QcLsn+  l+e+l     ++ +        +e++++l+ l+++lw+++ +     e+++a++k+ ++f+g++q
   Q: 101  QGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAAPG------RAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQ 183
           6****************************9955555555......479***************************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +Da Efl +lld+++e+l+ +++ p++e+   + +++s++  +++ +   ++s+++  Fq q++s+++c++c ++s++++pfl +slp+
   Q: 184  HDALEFLLWLLDRVHEDLEGSSRGPVSEKLPPEATKTSENclSPSAQLPLGQSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPI 272
           ******************999999999998888888888777889999999************************************** PP
   S: 177  pgkeetkke................................................................................ 185
           p ++++ ++                                                                                
   Q: 273  PLRQTRFLSvtlvfpsksqrflrvglavpilstvaalrkmvaeeggipadevilvelypsgfqrsffdeedlntiaegdnvyafqvpps 361
           ****98888******************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 362  psqgtlsahplglsvsprlvaregqrfslslhseskvlilfcnlvgsgqqasrfgppfliredravswaqlqqsilskvrhlmkseapv 450
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 451  qnlgslfsirvvglsvacsylspkdsrplchwavdrvlhlrkpggpphvklavewessvkerlfgslqeeraqdadsvwqqqqahqqhs 539
           ***************************************************************************************** PP
   S: 186  .slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfctspeekq 272
            +l++c++ +tkee+l ++++++c++c+ +q+   kl+l++lP++Li+hLkRf   + +++r+k+++ v+fpl+ L+++p++++++++ 
   Q: 540  cTLDECFQFYTKEEQLAQDDAWKCPHCQVLQQGMVKLSLWTLPDILIIHLKRF--CQVGERRNKLSTLVKFPLSgLNMAPHVAQRSTSP 626
           *****************************************************..88899************************87777 PP
   S: 273  ke....................kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           +                     +  Y+L+av++H+G+l++GHY+ay++n  +g+W+ +dDs+V++++e+ev++   + aY+lfY++r
   Q: 627  EAglgpwpswkqpgclptsyplDFLYDLYAVCNHHGNLQGGHYTAYCRNsLDGQWYSYDDSTVEPLREDEVNT---RGAYILFYQKR 710
           66999999999999**9***99***************************55788*******************...********985 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MDPGPGDAAG GGPLAPRPRR RRSLRRLFSR FLLALGSRSR PGDSPPRPQP GHCDGDGEGG 60
FACAPGPVPA VPGSPGEERP PGPQPQLQLP AGDGARPPGA QGLKNHGNTC FMNAVVQCLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGCACCAGG CGCCTTAGCG AAGCTGTAGG GCCTGCTGGC CGCTCGTCCT CCTCGGGCCC 60
GGGGGCTCCG CGCCTGGAGC TGCGCCGGCC GCAGCCATGG ACCCGGGCCC CGGGGACGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

nle:100595671

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	77.37	0.00e+00	1437.00
IUUC-Aca-004436	Anolis carolinensis	54.14	0.00e+00	800.00
IUUC-Ame-011153	Astyanax mexicanus	50.91	0.00e+00	880.00
IUUC-Bta-013560	Bos taurus	79.65	0.00e+00	1577.00
IUUC-Cja-018737	Callithrix jacchus	92.60	0.00e+00	1872.00
IUUC-Cfa-020347	Canis familiaris	77.38	0.00e+00	1473.00
IUUC-Csa-023656	Chlorocebus sabaeus	97.76	0.00e+00	1947.00
IUUC-Cho-024864	Choloepus hoffmanni	72.16	0.00e+00	918.00
IUUC-Dre-028066	Danio rerio	50.00	0.00e+00	905.00
IUUC-Dno-028855	Dasypus novemcinctus	72.82	0.00e+00	1365.00
IUUC-Dor-030475	Dipodomys ordii	88.80	0.00e+00	725.00
IUUC-Dme-032088	Drosophila melanogaster	36.39	5.00e-110	392.00
IUUC-Eca-034147	Equus caballus	85.06	0.00e+00	1467.00
IUUC-Eeu-034703	Erinaceus europaeus	62.02	0.00e+00	752.00
IUUC-Fca-036550	Felis catus	73.95	0.00e+00	1247.00
IUUC-Gac-042087	Gasterosteus aculeatus	51.12	0.00e+00	893.00
IUUC-Ggo-045171	Gorilla gorilla	98.44	0.00e+00	1956.00
IUUC-Hsa-045961	Homo sapiens	98.60	0.00e+00	1967.00
IUUC-Itr-048673	Ictidomys tridecemlineatus	75.53	0.00e+00	684.00
IUUC-Loc-052852	Lepisosteus oculatus	63.19	0.00e+00	931.00
IUUC-Laf-054033	Loxodonta africana	78.38	0.00e+00	1549.00
IUUC-Mcc-055431	Macaca mulatta	97.08	0.00e+00	1952.00
IUUC-Mmr-061035	Microcebus murinus	86.60	0.00e+00	1674.00
IUUC-Mdo-062172	Monodelphis domestica	64.81	0.00e+00	970.00
IUUC-Mmu-063966	Mus musculus	80.51	0.00e+00	1575.00
IUUC-Mpu-066307	Mustela putorius furo	78.25	0.00e+00	1419.00
IUUC-Opr-070499	Ochotona princeps	74.23	0.00e+00	1393.00
IUUC-Ont-071920	Oreochromis niloticus	52.80	0.00e+00	945.00
IUUC-Ocu-074014	Oryctolagus cuniculus	83.82	0.00e+00	1211.00
IUUC-Ola-086360	Oryzias latipes	53.04	0.00e+00	946.00
IUUC-Oga-088202	Otolemur garnettii	83.64	0.00e+00	1689.00
IUUC-Oar-089819	Ovis aries	77.49	0.00e+00	1479.00
IUUC-Ptr-091076	Pan troglodytes	98.23	0.00e+00	1959.00
IUUC-Pan-092248	Papio anubis	97.38	0.00e+00	1935.00
IUUC-Pfo-096534	Poecilia formosa	60.39	0.00e+00	820.00
IUUC-Pab-098453	Pongo abelii	96.28	0.00e+00	1899.00
IUUC-Pca-100290	Procavia capensis	63.53	0.00e+00	731.00
IUUC-Pva-102317	Pteropus vampyrus	73.73	0.00e+00	1400.00
IUUC-Rno-104948	Rattus norvegicus	78.32	0.00e+00	1410.00
IUUC-Sha-106558	Sarcophilus harrisii	57.52	0.00e+00	1142.00
IUUC-Sar-113105	Sorex araneus	63.88	0.00e+00	1057.00
IUUC-Ssc-115312	Sus scrofa	79.88	0.00e+00	1554.00
IUUC-Tru-117995	Takifugu rubripes	63.32	0.00e+00	909.00
IUUC-Tsy-119325	Tarsius syrichta	77.98	0.00e+00	771.00
IUUC-Tni-120517	Tetraodon nigroviridis	58.57	0.00e+00	865.00
IUUC-Tbe-127439	Tupaia belangeri	71.68	3.00e-144	506.00
IUUC-Ttr-128829	Tursiops truncatus	72.96	0.00e+00	1394.00
IUUC-Vpa-130306	Vicugna pacos	81.86	0.00e+00	634.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence