iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001746

Ensembl Protein ID

ENSAMEP00000015373.1

UniProt Accession

G1M7Q3; G1M7Q3_AILME

Genbank Protein ID

ENSAMEP00000015373

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01100132

Gene Name

TLE1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000014488.1	ENSAMET00000016012.1	ENSAMEP00000015373.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-21	75.9	622	660

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 622  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 660
           8***********999*********************998 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

ATAAARAMFP QSRHPTPHQA AGQPFKFTIP ESLDRIKEEF QFLQAQYHSL KLECEKLASE 60
KTEMQRHYVM YYEMSYGLNI EMHKQTEIAK RLNTICAQVI PFLSQEHQQQ VAQAVERAKQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTACGGCCG CCGCCAGAGC GATGTTCCCG CAGAGCCGGC ACCCGGTGAG GCGCAGCAGG 60
GTGCTGGGTG GAGGGGCAAA GCATTGGGTT GGGGGTGGGG TGAGGATGGG CGTTCTTCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0001106--F:RNA polymerase II transcription corepressor activity
GO:2000811--P:negative regulation of anoikis
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0010628--P:positive regulation of gene expression

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003594	Anas platyrhynchos	91.55	0.00e+00	1196.00
IUUC-Aca-005053	Anolis carolinensis	89.94	0.00e+00	1231.00
IUUC-Bta-012646	Bos taurus	84.20	0.00e+00	1199.00
IUUC-Cfa-020611	Canis familiaris	92.66	0.00e+00	1108.00
IUUC-Cpo-022495	Cavia porcellus	92.93	0.00e+00	1226.00
IUUC-Dno-029011	Dasypus novemcinctus	94.84	0.00e+00	1254.00
IUUC-Ete-032533	Echinops telfairi	83.16	0.00e+00	1136.00
IUUC-Eca-033351	Equus caballus	93.44	0.00e+00	1231.00
IUUC-Eeu-034666	Erinaceus europaeus	95.30	0.00e+00	1028.00
IUUC-Fca-036030	Felis catus	85.32	0.00e+00	1207.00
IUUC-Fal-036696	Ficedula albicollis	93.05	0.00e+00	1199.00
IUUC-Gga-041113	Gallus gallus	93.68	0.00e+00	1302.00
IUUC-Ggo-045164	Gorilla gorilla	93.19	0.00e+00	1244.00
IUUC-Hsa-047011	Homo sapiens	93.19	0.00e+00	1244.00
IUUC-Itr-048974	Ictidomys tridecemlineatus	84.97	0.00e+00	1206.00
IUUC-Lch-049943	Latimeria chalumnae	84.15	0.00e+00	1109.00
IUUC-Loc-052819	Lepisosteus oculatus	87.39	0.00e+00	1182.00
IUUC-Laf-053862	Loxodonta africana	94.60	0.00e+00	1028.00
IUUC-Mmr-061207	Microcebus murinus	92.10	0.00e+00	1220.00
IUUC-Mdo-062493	Monodelphis domestica	94.45	0.00e+00	1302.00
IUUC-Mmu-063795	Mus musculus	90.32	0.00e+00	1220.00
IUUC-Mlu-067047	Myotis lucifugus	94.97	0.00e+00	1240.00
IUUC-Nle-069684	Nomascus leucogenys	93.06	0.00e+00	1238.00
IUUC-Opr-071172	Ochotona princeps	92.42	0.00e+00	1206.00
IUUC-Ont-072102	Oreochromis niloticus	78.50	0.00e+00	1159.00
IUUC-Oan-072842	Ornithorhynchus anatinus	82.72	0.00e+00	1177.00
IUUC-Ocu-074592	Oryctolagus cuniculus	91.61	0.00e+00	1261.00
IUUC-Ola-087267	Oryzias latipes	77.59	0.00e+00	1076.00
IUUC-Oga-088629	Otolemur garnettii	94.95	0.00e+00	1024.00
IUUC-Oar-089551	Ovis aries	92.17	0.00e+00	1208.00
IUUC-Ptr-091207	Pan troglodytes	92.80	0.00e+00	1238.00
IUUC-Psi-093594	Pelodiscus sinensis	92.41	0.00e+00	1224.00
IUUC-Pfo-096239	Poecilia formosa	78.51	0.00e+00	1147.00
IUUC-Pab-097687	Pongo abelii	93.12	0.00e+00	1228.00
IUUC-Pva-102355	Pteropus vampyrus	90.94	0.00e+00	1144.00
IUUC-Rno-106027	Rattus norvegicus	93.42	0.00e+00	1271.00
IUUC-Sha-107419	Sarcophilus harrisii	90.05	0.00e+00	1226.00
IUUC-Sar-113585	Sorex araneus	81.53	0.00e+00	684.00
IUUC-Ssc-116151	Sus scrofa	93.06	0.00e+00	1226.00
IUUC-Tgu-117387	Taeniopygia guttata	93.55	0.00e+00	1285.00
IUUC-Tru-118327	Takifugu rubripes	65.82	0.00e+00	933.00
IUUC-Tsy-119342	Tarsius syrichta	90.77	0.00e+00	936.00
IUUC-Vpa-130577	Vicugna pacos	69.67	7.00e-154	537.00
IUUC-Xtr-131792	Xenopus tropicalis	85.66	0.00e+00	1186.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence