iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117924

UUCD1 version

UUC-TaR-01033

Ensembl Protein ID

ENSTRUP00000027680.1

UniProt Accession

H2TSM2; H2TSM2_TAKRU

Protein Name

Uncharacterized protein

Gene Name

ube2a

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000010964.1	ENSTRUT00000027789.1	ENSTRUP00000027680.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	6.90e-51	172.9	8	152

Active Site

Position(s)	Description	Evidence
98	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeg..........gvFkleiefpedYPfkPPkvkfltkifhPnvyenG 79
           Rl++++k+l++dpp+g+s  p+++ +++ w+++i+Gpe+tp+e+          g+Fkl+ief+e+YP kPP+v+f++k+fhPnvy++G
   Q: 8    RLMRDFKRLQEDPPAGVSGAPSEN-NIMVWNAVIFGPEGTPFEDviyvftllllGTFKLTIEFTEEYPNKPPTVRFISKMFHPNVYADG 95
           9**********************9.9*****************86666666666789******************************** PP
   S: 80   kvClsilkeeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Cl+il+  ++Wsp+++v+s+l+siqsll+epnp+sp+n++aa+l+++n++ey+k+v+
   Q: 96   SICLDILQ--NRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVS 152
           *******9..**********************************************996 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MSTPARRRLM RDFKRLQEDP PAGVSGAPSE NNIMVWNAVI FGPEGTPFED VIYVFTLLLL 60
GTFKLTIEFT EEYPNKPPTV RFISKMFHPN VYADGSICLD ILQNRWSPTY DVSSILTSIQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAACTC CAGCAAGACG ACGTTTAATG AGAGACTTTA AACGGTAAGC GAAAGAACAC 60
ATTAGTTCTT TAGCTCAGGT TAGCCTTTTA CCTTTAGCCT CTCGGCATAC AACGTCATCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006281--P:DNA repair
GO:0016574--P:histone ubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004063	Anas platyrhynchos	89.26	1.00e-74	271.00
IUUC-Ame-011594	Astyanax mexicanus	92.59	3.00e-85	306.00
IUUC-Cja-018783	Callithrix jacchus	92.59	3.00e-85	306.00
IUUC-Cfa-020646	Canis familiaris	92.55	5.00e-84	303.00
IUUC-Cpo-021323	Cavia porcellus	93.21	2.00e-85	306.00
IUUC-Csa-023588	Chlorocebus sabaeus	92.59	3.00e-85	306.00
IUUC-Dre-028358	Danio rerio	92.59	3.00e-85	306.00
IUUC-Eca-033562	Equus caballus	90.85	2.00e-83	300.00
IUUC-Eeu-035191	Erinaceus europaeus	74.69	5.00e-63	233.00
IUUC-Fca-036581	Felis catus	92.59	3.00e-85	306.00
IUUC-Fal-037474	Ficedula albicollis	90.70	5.00e-65	238.00
IUUC-Gmo-038517	Gadus morhua	92.59	3.00e-85	306.00
IUUC-Gga-040588	Gallus gallus	92.59	3.00e-85	306.00
IUUC-Gac-041504	Gasterosteus aculeatus	92.59	7.00e-85	305.00
IUUC-Ggo-044896	Gorilla gorilla	92.59	3.00e-85	306.00
IUUC-Hsa-046383	Homo sapiens	92.59	3.00e-85	306.00
IUUC-Itr-048507	Ictidomys tridecemlineatus	92.59	3.00e-85	306.00
IUUC-Lch-049964	Latimeria chalumnae	92.59	3.00e-85	306.00
IUUC-Loc-051731	Lepisosteus oculatus	92.59	3.00e-85	306.00
IUUC-Laf-053680	Loxodonta africana	92.59	3.00e-85	306.00
IUUC-Mcc-055546	Macaca mulatta	92.59	8.00e-85	306.00
IUUC-Meu-056231	Macropus eugenii	92.59	3.00e-85	306.00
IUUC-Mdo-062292	Monodelphis domestica	92.59	3.00e-85	306.00
IUUC-Mmu-063680	Mus musculus	92.59	3.00e-85	306.00
IUUC-Nle-069121	Nomascus leucogenys	92.59	3.00e-85	306.00
IUUC-Ocu-074550	Oryctolagus cuniculus	92.59	6.00e-85	306.00
IUUC-Olo-081018	Oryza longistaminata	66.87	1.00e-62	232.00
IUUC-Ola-086407	Oryzias latipes	92.59	3.00e-85	306.00
IUUC-Oga-088659	Otolemur garnettii	92.59	3.00e-85	306.00
IUUC-Ptr-091305	Pan troglodytes	92.59	3.00e-85	306.00
IUUC-Pan-092740	Papio anubis	92.59	8.00e-85	306.00
IUUC-Psi-094094	Pelodiscus sinensis	92.59	3.00e-85	306.00
IUUC-Pfo-096656	Poecilia formosa	91.98	5.00e-85	305.00
IUUC-Pab-097972	Pongo abelii	92.59	3.00e-85	306.00
IUUC-Pca-100906	Procavia capensis	86.42	2.00e-77	280.00
IUUC-Pva-102380	Pteropus vampyrus	91.36	2.00e-83	300.00
IUUC-Rno-105577	Rattus norvegicus	94.44	1.00e-88	318.00
IUUC-Ssc-116265	Sus scrofa	92.59	3.00e-85	306.00
IUUC-Tgu-117383	Taeniopygia guttata	92.59	3.00e-85	306.00
IUUC-Tni-119743	Tetraodon nigroviridis	90.12	1.00e-81	294.00
IUUC-Ttr-129050	Tursiops truncatus	91.93	2.00e-82	296.00
IUUC-Xtr-132301	Xenopus tropicalis	92.59	3.00e-85	306.00
IUUC-Xma-133937	Xiphophorus maculatus	92.59	3.00e-85	306.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence