iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033293

UUCD1 version

UUC-EqC-00941

Ensembl Protein ID

ENSECAP00000023096.1

UniProt Accession

F7BRL2; F7BRL2_HORSE

Protein Name

Uncharacterized protein

Gene Name

UBE2D2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000026911.1	ENSECAT00000028887.1	ENSECAP00000023096.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.50e-55	186.2	13	144
UBD/UBC-like/UBD_UBC	8.20e-84	278.8	12	147

Active Site

Position(s)	Description	Evidence
90	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekW 92
           +el++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  ++W
   Q: 13   HELNDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--SQW 98
           79*******************.9************************************************************9..*** PP
   S: 93   spalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           spal++++vllsi+sll++pnp++pl  e+a+++k++re+y++++r
   Q: 99   SPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAR 144
           ******************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 3    kkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsa 91
           k+el+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws+
   Q: 12   KHELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSP 100
           68*************************************************************************************** PP
   S: 92   altlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           alt+skvlls+csll+d++pddplv+eiariyktd+eky+riarewt
   Q: 101  ALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWT 147
           **********************************************8 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

EIVRIGSSEG KKHELNDLAR DPPAQCSAGP VGDDMFHWQA TIMGPNDSPY QGGVFFLTIH 60
FPTDYPFKPP KVAFTTRIYH PNINSNGSIC LDILRSQWSP ALTISKVLLS ICSLLCDPNP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAATTGTTA GAATAGGAAG TTCAGAAGGA AAAAAACATG ACTCTTGAGG GAGGAGAGTA 60
GTAGAGGGAG AAGCATTTTA TTCCTTGAGG TTGCCAAACG TAGTCAGAAA CTAACACTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001778	Ailuropoda melanoleuca	100.00	3.00e-81	293.00
IUUC-Atr-002861	Amborella trichopoda	81.29	1.00e-67	248.00
IUUC-Apl-003199	Anas platyrhynchos	100.00	2.00e-81	293.00
IUUC-Aca-005236	Anolis carolinensis	100.00	1.00e-81	294.00
IUUC-Ang-009725	Aspergillus niger	84.80	4.00e-62	229.00
IUUC-Ame-011831	Astyanax mexicanus	95.74	2.00e-79	287.00
IUUC-Bta-013158	Bos taurus	100.00	1.00e-81	294.00
IUUC-Cja-019886	Callithrix jacchus	100.00	1.00e-81	294.00
IUUC-Cfa-020436	Canis familiaris	100.00	1.00e-81	294.00
IUUC-Cpo-021714	Cavia porcellus	97.84	1.00e-79	288.00
IUUC-Dre-027758	Danio rerio	98.56	2.00e-80	290.00
IUUC-Dno-028952	Dasypus novemcinctus	100.00	2.00e-81	293.00
IUUC-Ete-032295	Echinops telfairi	100.00	2.00e-81	293.00
IUUC-Gmo-038835	Gadus morhua	94.24	1.00e-77	281.00
IUUC-Ggr-039912	Gaeumannomyces graminis	79.17	2.00e-65	241.00
IUUC-Gga-040758	Gallus gallus	100.00	1.00e-81	294.00
IUUC-Gac-042231	Gasterosteus aculeatus	97.12	2.00e-79	286.00
IUUC-Ggo-045375	Gorilla gorilla	97.22	5.00e-82	295.00
IUUC-Hsa-045885	Homo sapiens	100.00	1.00e-81	294.00
IUUC-Itr-048882	Ictidomys tridecemlineatus	100.00	1.00e-81	294.00
IUUC-Lch-050583	Latimeria chalumnae	90.78	2.00e-74	270.00
IUUC-Lpe-050972	Leersia perrieri	80.58	9.00e-68	248.00
IUUC-Loc-052788	Lepisosteus oculatus	97.86	1.00e-80	291.00
IUUC-Laf-053580	Loxodonta africana	100.00	2.00e-81	293.00
IUUC-Mcc-054673	Macaca mulatta	97.22	9.00e-82	295.00
IUUC-Mmr-061474	Microcebus murinus	100.00	2.00e-81	293.00
IUUC-Mdo-062962	Monodelphis domestica	100.00	1.00e-81	294.00
IUUC-Mmu-063518	Mus musculus	100.00	1.00e-81	294.00
IUUC-Mpu-066604	Mustela putorius furo	100.00	1.00e-82	297.00
IUUC-Nle-069800	Nomascus leucogenys	98.56	1.00e-78	284.00
IUUC-Ont-071766	Oreochromis niloticus	98.56	1.00e-80	291.00
IUUC-Ocu-074315	Oryctolagus cuniculus	100.00	1.00e-81	294.00
IUUC-Obr-076658	Oryza brachyantha	80.58	9.00e-68	248.00
IUUC-Opu-083833	Oryza punctata	80.58	1.00e-67	248.00
IUUC-Ola-086331	Oryzias latipes	98.56	1.00e-80	291.00
IUUC-Ptr-090707	Pan troglodytes	100.00	1.00e-81	294.00
IUUC-Pan-092143	Papio anubis	100.00	1.00e-81	294.00
IUUC-Pma-094405	Petromyzon marinus	95.49	2.00e-74	270.00
IUUC-Pfo-096753	Poecilia formosa	98.56	1.00e-80	291.00
IUUC-Pab-097764	Pongo abelii	100.00	1.00e-81	294.00
IUUC-Ptt-103723	Puccinia triticina	77.86	2.00e-61	227.00
IUUC-Sar-113302	Sorex araneus	100.00	2.00e-81	293.00
IUUC-Tru-118272	Takifugu rubripes	98.56	3.00e-80	289.00
IUUC-Tsy-119491	Tarsius syrichta	97.12	8.00e-77	279.00
IUUC-Tni-120056	Tetraodon nigroviridis	98.56	3.00e-80	289.00
IUUC-Tbe-127609	Tupaia belangeri	100.00	7.00e-68	248.00
IUUC-Vpa-130446	Vicugna pacos	96.67	3.00e-83	301.00
IUUC-Xtr-132329	Xenopus tropicalis	100.00	1.00e-81	294.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence