iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050114

Ensembl Protein ID

ENSLACP00000003363.1

UniProt Accession

H3A142; H3A142_LATCH

Genbank Protein ID

ENSLACP00000003363

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AFYH01152840

Gene Name

BLK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000003007.1	ENSLACT00000003393.1	ENSLACP00000003363.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.30e-14	54.1	4	59

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
              +lydy ++n+ +L+l+kG++v+v+      ++W+++++  ++ rG +P+nFv+k++
   Q: 4    IYVALYDYFPVNNKDLELRKGEKVRVL---ADKGDWWMAQSLSSEARGYVPSNFVAKVN 59
           5679***********************...88899**********************97 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

DGNIYVALYD YFPVNNKDLE LRKGEKVRVL ADKGDWWMAQ SLSSEARGYV PSNFVAKVNT 60
LEVEKWFCKN LSRKDAERLL QTPGNKAGAF LVRESETSKG AYSLSLRDND STHGDVVKHY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGGAAATA TATATGTTGC ACTGTACGAT TATTTTCCAG TAAACAACAA GGACTTGGAG 60
CTTAGAAAAG GGGAGAAAGT GCGAGTCCTT GCAGAGTAAG TGATACAGTC AAGTACAGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002133	Ailuropoda melanoleuca	73.32	0.00e+00	706.00
IUUC-Apl-003307	Anas platyrhynchos	75.45	0.00e+00	734.00
IUUC-Aca-004357	Anolis carolinensis	70.14	0.00e+00	676.00
IUUC-Ame-010642	Astyanax mexicanus	70.69	0.00e+00	696.00
IUUC-Bta-012400	Bos taurus	72.77	0.00e+00	706.00
IUUC-Cfa-021056	Canis familiaris	73.36	0.00e+00	701.00
IUUC-Cpo-021779	Cavia porcellus	73.36	0.00e+00	703.00
IUUC-Csa-023557	Chlorocebus sabaeus	72.10	0.00e+00	698.00
IUUC-Dre-027517	Danio rerio	71.14	0.00e+00	704.00
IUUC-Eca-034218	Equus caballus	71.97	0.00e+00	694.00
IUUC-Eeu-035095	Erinaceus europaeus	56.21	4.00e-143	501.00
IUUC-Fca-036015	Felis catus	72.20	0.00e+00	695.00
IUUC-Fal-036946	Ficedula albicollis	74.21	0.00e+00	722.00
IUUC-Gga-040822	Gallus gallus	75.17	0.00e+00	740.00
IUUC-Hsa-046719	Homo sapiens	71.65	0.00e+00	692.00
IUUC-Itr-048323	Ictidomys tridecemlineatus	73.36	0.00e+00	699.00
IUUC-Loc-052326	Lepisosteus oculatus	75.84	0.00e+00	730.00
IUUC-Laf-053387	Loxodonta africana	71.30	0.00e+00	689.00
IUUC-Mcc-055026	Macaca mulatta	72.10	0.00e+00	698.00
IUUC-Mga-059427	Meleagris gallopavo	74.55	0.00e+00	729.00
IUUC-Mmr-061660	Microcebus murinus	73.59	0.00e+00	704.00
IUUC-Mdo-062318	Monodelphis domestica	72.85	0.00e+00	698.00
IUUC-Mmu-063325	Mus musculus	74.04	0.00e+00	702.00
IUUC-Mpu-066582	Mustela putorius furo	72.87	0.00e+00	704.00
IUUC-Nle-069624	Nomascus leucogenys	72.20	0.00e+00	697.00
IUUC-Ont-072266	Oreochromis niloticus	72.04	0.00e+00	699.00
IUUC-Ocu-073907	Oryctolagus cuniculus	72.54	0.00e+00	700.00
IUUC-Ola-086668	Oryzias latipes	70.18	0.00e+00	683.00
IUUC-Oga-088057	Otolemur garnettii	72.20	0.00e+00	695.00
IUUC-Pan-092173	Papio anubis	72.23	0.00e+00	696.00
IUUC-Psi-093895	Pelodiscus sinensis	75.39	0.00e+00	732.00
IUUC-Pfo-096608	Poecilia formosa	70.92	0.00e+00	697.00
IUUC-Pab-097598	Pongo abelii	72.91	0.00e+00	699.00
IUUC-Pva-102135	Pteropus vampyrus	71.75	0.00e+00	690.00
IUUC-Rno-104891	Rattus norvegicus	74.27	0.00e+00	707.00
IUUC-Sha-107192	Sarcophilus harrisii	73.76	0.00e+00	704.00
IUUC-Ssc-115696	Sus scrofa	71.97	0.00e+00	697.00
IUUC-Tgu-117056	Taeniopygia guttata	74.21	0.00e+00	725.00
IUUC-Tru-117621	Takifugu rubripes	69.13	0.00e+00	672.00
IUUC-Ttr-128457	Tursiops truncatus	72.87	0.00e+00	699.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence