iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ola-087389

Ensembl Protein ID

ENSORLP00000009305.1

UniProt Accession

H2LT87; H2LT87_ORYLA

Genbank Protein ID

ENSORLP00000009305

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

BAAF04033175

Gene Name

abl1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000007426.1	ENSORLT00000009306.1	ENSORLP00000009305.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.00e-14	53.0	87	144

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++++++W+++  ++++ +G +P+n+++ ++
   Q: 87   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNHNGEWCEA--QTKNGQGWVPSNYITPVN 144
           68899************************.***********..79999**********997 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

PTWIVPAAAW HPALMGQQPG KFVGDQRRPS LPAFIKGGKK DLPRHVNQPM NVFDWHEALQ 60
RPEFGLGDAA RWNSKENLLA GPSVNDPNLF VALYDFVASG DNTLSITKGE KLRVLGYNHN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGACTTGGA TAGTCCCGGC TGCAGCCTGG CACCCTGCCC TTATGGGGCA GCAGCCGGGA 60
AAGTTTGTCG GGGACCAAAG GAGACCCAGT CTTCCAGCCT TTATTAAGGG GGGAAAGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR033221--ABL1
IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001550	Ailuropoda melanoleuca	72.20	0.00e+00	1094.00
IUUC-Apl-003452	Anas platyrhynchos	64.53	0.00e+00	1194.00
IUUC-Aca-005312	Anolis carolinensis	73.01	0.00e+00	1056.00
IUUC-Ame-011903	Astyanax mexicanus	75.31	0.00e+00	1181.00
IUUC-Bta-012351	Bos taurus	68.46	0.00e+00	1054.00
IUUC-Cja-019491	Callithrix jacchus	64.33	0.00e+00	1259.00
IUUC-Cfa-021256	Canis familiaris	64.27	0.00e+00	1256.00
IUUC-Cpo-022046	Cavia porcellus	73.66	0.00e+00	1110.00
IUUC-Csa-023046	Chlorocebus sabaeus	64.38	0.00e+00	1226.00
IUUC-Dre-028190	Danio rerio	70.75	0.00e+00	1293.00
IUUC-Dno-029853	Dasypus novemcinctus	68.74	0.00e+00	1099.00
IUUC-Dor-030635	Dipodomys ordii	66.28	0.00e+00	973.00
IUUC-Dme-032098	Drosophila melanogaster	74.68	0.00e+00	773.00
IUUC-Eca-033720	Equus caballus	68.86	0.00e+00	1052.00
IUUC-Eeu-035173	Erinaceus europaeus	64.90	0.00e+00	1036.00
IUUC-Fca-035967	Felis catus	72.20	0.00e+00	1092.00
IUUC-Fal-036723	Ficedula albicollis	64.10	0.00e+00	1204.00
IUUC-Gmo-039550	Gadus morhua	80.17	0.00e+00	1208.00
IUUC-Gga-040481	Gallus gallus	64.01	0.00e+00	1181.00
IUUC-Gac-041643	Gasterosteus aculeatus	76.02	0.00e+00	1599.00
IUUC-Gma-043854	Glycine max	30.49	4.00e-21	96.70
IUUC-Ggo-045299	Gorilla gorilla	63.83	0.00e+00	1263.00
IUUC-Hsa-047033	Homo sapiens	86.49	2.00e-32	129.00
IUUC-Itr-048685	Ictidomys tridecemlineatus	76.90	0.00e+00	915.00
IUUC-Lch-050530	Latimeria chalumnae	69.28	0.00e+00	1113.00
IUUC-Loc-052430	Lepisosteus oculatus	81.64	0.00e+00	988.00
IUUC-Laf-053609	Loxodonta africana	67.16	0.00e+00	1102.00
IUUC-Mcc-055654	Macaca mulatta	64.55	0.00e+00	1280.00
IUUC-Meu-056488	Macropus eugenii	60.84	0.00e+00	902.00
IUUC-Mga-059270	Meleagris gallopavo	64.88	0.00e+00	1196.00
IUUC-Mmr-060593	Microcebus murinus	72.17	0.00e+00	1053.00
IUUC-Mdo-062227	Monodelphis domestica	75.13	0.00e+00	1052.00
IUUC-Mmu-064002	Mus musculus	69.99	0.00e+00	1137.00
IUUC-Mpu-066197	Mustela putorius furo	72.29	0.00e+00	1097.00
IUUC-Mlu-067255	Myotis lucifugus	64.25	0.00e+00	1199.00
IUUC-Nle-069977	Nomascus leucogenys	59.45	0.00e+00	1113.00
IUUC-Opr-070327	Ochotona princeps	63.13	0.00e+00	900.00
IUUC-Ont-072307	Oreochromis niloticus	75.98	0.00e+00	1579.00
IUUC-Oan-073100	Ornithorhynchus anatinus	68.49	0.00e+00	1071.00
IUUC-Ocu-074892	Oryctolagus cuniculus	70.83	0.00e+00	964.00
IUUC-Oga-088145	Otolemur garnettii	65.21	0.00e+00	1208.00
IUUC-Oar-090432	Ovis aries	71.87	0.00e+00	1036.00
IUUC-Ptr-090800	Pan troglodytes	64.47	0.00e+00	1275.00
IUUC-Pan-092279	Papio anubis	76.35	0.00e+00	925.00
IUUC-Psi-093078	Pelodiscus sinensis	65.95	0.00e+00	1237.00
IUUC-Pma-094420	Petromyzon marinus	77.68	0.00e+00	890.00
IUUC-Pfo-096979	Poecilia formosa	76.83	0.00e+00	1510.00
IUUC-Pab-097949	Pongo abelii	76.35	0.00e+00	924.00
IUUC-Pca-100874	Procavia capensis	92.11	0.00e+00	689.00
IUUC-Pva-102415	Pteropus vampyrus	71.46	0.00e+00	1083.00
IUUC-Rno-105682	Rattus norvegicus	69.02	0.00e+00	1132.00
IUUC-Sha-106711	Sarcophilus harrisii	69.88	0.00e+00	1072.00
IUUC-Ssc-115472	Sus scrofa	73.93	0.00e+00	1100.00
IUUC-Tgu-117037	Taeniopygia guttata	64.75	0.00e+00	1262.00
IUUC-Tru-118324	Takifugu rubripes	68.70	0.00e+00	1427.00
IUUC-Tsy-119216	Tarsius syrichta	87.76	0.00e+00	1019.00
IUUC-Tni-119950	Tetraodon nigroviridis	68.79	0.00e+00	1398.00
IUUC-Ttr-128209	Tursiops truncatus	64.57	0.00e+00	1256.00
IUUC-Vpa-130800	Vicugna pacos	76.57	0.00e+00	909.00
IUUC-Xtr-132477	Xenopus tropicalis	65.80	0.00e+00	922.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence