iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062239

UUCD1 version

UUC-MoD-01157

Ensembl Protein ID

ENSMODP00000015606.2

UniProt Accession

F6Q4L4; F6Q4L4_MONDO

Protein Name

Uncharacterized protein

Gene Name

LOC100619289

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000012469.2	ENSMODT00000015895.2	ENSMODP00000015606.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-53	182.8	412	779

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeel........................w..ks 63
           Gl N gN CY+N++LQ+L+++p++ +l++     +k+++   + +++++++s+ +l++e+                           +s
   Q: 412  GLINKGNWCYINATLQALVACPPMYHLMKFiPVYSKVQW---PCTSTPMVDSFVRLMNEFtnmpippkakqalgdkivrdisliSlsHS 497
           9***************************99656667776...57788888888888888855565555555555555555544313466 PP
   S: 64   kkkavsprellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk..................eknkpkeeeeeedkselsde.... 129
              a++p+ +++ l  +++++s + +q+Da+E+l f+l++l+ee+ +                                          
   Q: 498  PGAAFEPTYIYRLLTVIKSSLSeKGRQEDAEEYLGFILNGLHEEMLNlkklllpnnekfsvsngpD------------------Aqsvh 568
           666******9999999999966599********************444556664444444333321..................02333 PP
   S: 130  .......................aeekkkkknk......slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqd 189
                                  +        +      ++i+ +F+g+l+ +++ ++  ++s + +pf++l+l++++++     ++qd
   Q: 569  edeqgqgegsedeweqvgprnktSVT------RqadfiqTPITGIFGGHLR-SVVYQQSSKESATLQPFFTLQLEIQSDKIH---TVQD 647
           34556666666656666665333333......1444666***********9.688999999*******************88...**** PP
   S: 190  cLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke...k 275
           +Les +++e+++g    y++k k+++e +++++l+klP+ L+lhLkRf ++++++++  + k++e+p  L++s+ + sp  k+k+   +
   Q: 648  ALESLVARESVQG----YTTKTKQEVEISQRVTLEKLPP-LVLHLKRFVYEKTGGCQ-TLIKNIEYPVVLEMSRELLSPGVKNKHfkgH 730
           ************8....99999****************9.89********9999997.89999**********999997766665777* PP
   S: 276  kkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeev 322
           ++Y+L+avv+H+G s+ +GH +a+v +   + Wl++dD+ V+++   ++
   Q: 731  RNYRLFAVVYHHGnSAPGGHSTADVFQIGLNgWLCVDDQVVKPSASCTI 779
           ***************************87777*********99866555 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MALRGPQYVF GDIIPDEFNQ FFVTPRSSVE LPPYNETILC DTETPEELHD GEEYQRIEFG 60
VTEVIEQDES LLNNTDYSIS STLNPQAPEF ILGCTTSKKN HDDIHNETNY NSIDCQFTSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCCTCC GCGGCCCCCA GTATGTTTTT GGAGATATTA TTCCTGATGA GTTCAATCAG 60
TTTTTTGTGA CTCCTCGTTC TTCTGTTGAG CTTCCACCAT ATAATGAAAC AATTTTGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009818--Ataxin-2_C
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS50235--USP_3

Pfam

PF07145--PAM2
PF00443--UCH

Gene Ontology

GO:0005769--C:early endosome
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence