iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033231

UUCD1 version

UUC-EqC-00942

Ensembl Protein ID

ENSECAP00000017572.1

UniProt Accession

F7CFT7; F7CFT7_HORSE

Protein Name

Uncharacterized protein

Gene Name

UBE2D4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000019978.1	ENSECAT00000021345.1	ENSECAP00000017572.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.10e-55	185.2	1	131
UBD/UBC-like/UBD_UBC	3.50e-81	270.3	1	134

Active Site

Position(s)	Description	Evidence
77	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 5    elkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWs 93
           el++l++dpp+++sa+pv + dl++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+tki+hPn+++nG++Cl+il+  ++Ws
   Q: 1    ELTDLQRDPPAQCSAGPVGD-DLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILR--SQWS 86
           799*****************.9************************************************************9..**** PP
   S: 94   palsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           pal+v++vllsi+sll++pnp++pl  e+a+++k++re+y++ +r
   Q: 87   PALTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADREKYNRLAR 131
           *****************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 5    elkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaal 93
           el dl+rd++aq+sa++v+ddlf+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+tkiyhpninsngsicldilrsqws+al
   Q: 1    ELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPAL 89
           899************************************************************************************** PP
   S: 94   tlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           t+skvlls+csll+d++pddplv+eia+ yk+d+eky+r arewt
   Q: 90   TVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADREKYNRLAREWT 134
           ********************************************8 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

ELTDLQRDPP AQCSAGPVGD DLFHWQATIM GPNDSPYQGG VFFLTIHFPT DYPFKPPKVA 60
FTTKIYHPNI NSNGSICLDI LRSQWSPALT VSKVLLSICS LLCDPNPDDP LVPEIAHTYK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGTCCGATC CGGCAGCGCC CGGCCCTTGG AGCCCGGGCC CGGGCCGCCC CCGTCCCCAG 60
CAGCGGGGTA GGATGCCGCT CAAGCCGTAC CCAGAAGTAA AGCGGCCCTC TCGCTTCTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0070979--P:protein K11-linked ubiquitination
GO:0044314--P:protein K27-linked ubiquitination
GO:0035519--P:protein K29-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afl-008709	Aspergillus flavus	81.88	9.00e-69	254.00
IUUC-Bol-015722	Brassica oleracea	82.73	8.00e-69	252.00
IUUC-Cja-019014	Callithrix jacchus	99.28	5.00e-81	292.00
IUUC-Cpo-021897	Cavia porcellus	99.28	1.00e-80	290.00
IUUC-Csa-023377	Chlorocebus sabaeus	99.28	1.00e-80	291.00
IUUC-Dre-028686	Danio rerio	99.28	6.00e-81	292.00
IUUC-Dor-030323	Dipodomys ordii	99.28	6.00e-81	292.00
IUUC-Gac-042534	Gasterosteus aculeatus	92.81	1.00e-75	274.00
IUUC-Ggo-045361	Gorilla gorilla	100.00	3.00e-81	293.00
IUUC-Hsa-045934	Homo sapiens	100.00	3.00e-81	293.00
IUUC-Loc-052838	Lepisosteus oculatus	100.00	3.00e-81	293.00
IUUC-Mcc-055421	Macaca mulatta	100.00	3.00e-81	293.00
IUUC-Mmr-061446	Microcebus murinus	97.12	3.00e-79	286.00
IUUC-Mdo-062413	Monodelphis domestica	99.28	1.00e-80	290.00
IUUC-Nle-069715	Nomascus leucogenys	100.00	3.00e-81	293.00
IUUC-Ont-072562	Oreochromis niloticus	96.40	4.00e-79	286.00
IUUC-Oan-073026	Ornithorhynchus anatinus	100.00	5.00e-81	292.00
IUUC-Ocu-073914	Oryctolagus cuniculus	97.84	1.00e-79	288.00
IUUC-Ome-081987	Oryza meridionalis	79.86	5.00e-67	246.00
IUUC-Ola-087515	Oryzias latipes	97.12	2.00e-79	287.00
IUUC-Olu-087615	Ostreococcus lucimarinus	77.70	1.00e-63	234.00
IUUC-Pan-092614	Papio anubis	100.00	8.00e-81	291.00
IUUC-Pfo-096867	Poecilia formosa	97.12	2.00e-79	287.00
IUUC-Pab-098760	Pongo abelii	99.28	1.00e-80	291.00
IUUC-Sit-109936	Setaria italica	82.01	1.00e-68	252.00
IUUC-Ssc-115391	Sus scrofa	100.00	3.00e-81	293.00
IUUC-Tsy-118832	Tarsius syrichta	97.84	1.00e-78	284.00
IUUC-Tca-121542	Theobroma cacao	82.01	4.00e-69	253.00
IUUC-Tbe-128122	Tupaia belangeri	96.77	7.00e-61	224.00
IUUC-Xtr-132238	Xenopus tropicalis	97.84	5.00e-80	289.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence