iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067855

Ensembl Protein ID

ENSMLUP00000012657.2

UniProt Accession

G1PNV9; G1PNV9_MYOLU

Genbank Protein ID

ENSMLUP00000012657

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02039111

Gene Name

NWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000013904.2	ENSMLUT00000013913.2	ENSMLUP00000012657.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-28	97.9	909	943
UBD/Beta-Prp	4.00e-57	193.7	863	1054

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcla.f.sdtllvsGsdDgtikvWDlrtg 33
           gHt++v+c+  f  +t+ +s+s+D t+++W l +g
   Q: 909  GHTGEVRCVTvFaRGTRAISASRDRTLRLWHLLSG 943
           8********977988***************98666 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee. 131
           ++l g+ +++ta+ +s ++k+lv g +D+t+ vwd +  + +h+l+gh+ +v+++++++ g + +s+s+drt+r+w+l +gq+  + 
   Q: 863  ATLTGCHKGITAMAWSLEEKLLVVGTQDGTVAVWDTEEHQAIHILTGHTGEVRCVTVFARGTRAISASRDRTLRLWHLLSGQEKFTi 949
           7899*******************************************************************************9996 PP
   S: 132  ..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvr 216
               s+  +v ++++v++  +++ s+s  ++v+ W+l+t++l+ + +g+  d+  +++   ++  l+++s+ + v lw+  tg++  
   Q: 950  wdGGSEDPAVPQSLHVDEARKVVYSAS-GSKVNAWNLETAELIFHIRGDASDPWICTAALASQAMLLTVSEGSVVSLWSSATGKVRG 1035
           666667778899999999666655555.5789**************************9999*********************9977 PP
   S: 217  tlnght....dnvksvrfs 231
           +++  +    ++++ v + 
   Q: 1036 KQHLSSikeeTPTCGVSVQ 1054
           7765443333555555555 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MDAEREALQT TAYPEVQTFC QKHGLMFEVV DLRWGIQHAQ ATDHMTTELC LEELDRCRET 60
SLGPAFVCLL GDQYGPCPVP TLIEEKEWEA LKAQLTARPG DLELVAHHFR RDENTVPPSY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGCGG AGAGAGAAGC TCTGCAGACG ACCGCGTACC CCGAAGTGCA GACCTTCTGC 60
CAAAAGCACG GCCTGATGTT TGAGGTAATC ATCACCTGCC CACGCCGCCT GCCTCCGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR025139--DUF4062
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF13271--DUF4062
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001525	Ailuropoda melanoleuca	86.26	0.00e+00	2706.00
IUUC-Apl-003467	Anas platyrhynchos	60.52	6.00e-83	300.00
IUUC-Ame-011400	Astyanax mexicanus	37.09	0.00e+00	992.00
IUUC-Bta-013223	Bos taurus	85.49	0.00e+00	2313.00
IUUC-Cel-018404	Caenorhabditis elegans	30.56	1.00e-109	392.00
IUUC-Cja-018773	Callithrix jacchus	80.63	0.00e+00	1519.00
IUUC-Cfa-020334	Canis familiaris	87.04	0.00e+00	2720.00
IUUC-Cpo-022316	Cavia porcellus	66.65	0.00e+00	1931.00
IUUC-Csa-023631	Chlorocebus sabaeus	82.17	0.00e+00	2534.00
IUUC-Cin-025646	Ciona intestinalis	32.14	2.00e-133	470.00
IUUC-Csv-026191	Ciona savignyi	26.36	5.00e-29	121.00
IUUC-Dre-028241	Danio rerio	36.25	0.00e+00	951.00
IUUC-Dno-029990	Dasypus novemcinctus	79.05	0.00e+00	702.00
IUUC-Dor-030869	Dipodomys ordii	57.91	2.00e-176	613.00
IUUC-Ete-033059	Echinops telfairi	83.98	0.00e+00	841.00
IUUC-Eca-033718	Equus caballus	81.11	0.00e+00	2526.00
IUUC-Fca-035748	Felis catus	85.13	0.00e+00	2473.00
IUUC-Gac-041507	Gasterosteus aculeatus	36.25	0.00e+00	763.00
IUUC-Ggo-044551	Gorilla gorilla	79.33	0.00e+00	2421.00
IUUC-Hsa-046787	Homo sapiens	81.50	0.00e+00	2528.00
IUUC-Itr-048104	Ictidomys tridecemlineatus	63.58	0.00e+00	1785.00
IUUC-Lch-049578	Latimeria chalumnae	47.59	0.00e+00	1431.00
IUUC-Loc-052039	Lepisosteus oculatus	41.47	0.00e+00	1249.00
IUUC-Laf-054240	Loxodonta africana	83.27	0.00e+00	2658.00
IUUC-Mcc-054657	Macaca mulatta	74.23	0.00e+00	2181.00
IUUC-Meu-056591	Macropus eugenii	64.43	0.00e+00	1163.00
IUUC-Mmr-061577	Microcebus murinus	78.66	0.00e+00	2428.00
IUUC-Mdo-062895	Monodelphis domestica	62.54	0.00e+00	1793.00
IUUC-Mmu-063866	Mus musculus	77.19	0.00e+00	2367.00
IUUC-Mpu-066510	Mustela putorius furo	84.86	0.00e+00	2698.00
IUUC-Nle-069557	Nomascus leucogenys	77.56	0.00e+00	2328.00
IUUC-Opr-071196	Ochotona princeps	62.94	3.00e-179	623.00
IUUC-Ont-072070	Oreochromis niloticus	35.91	0.00e+00	828.00
IUUC-Oan-073437	Ornithorhynchus anatinus	57.17	0.00e+00	1268.00
IUUC-Ocu-074941	Oryctolagus cuniculus	78.33	4.00e-53	200.00
IUUC-Ola-086624	Oryzias latipes	33.83	0.00e+00	708.00
IUUC-Oga-088313	Otolemur garnettii	83.45	0.00e+00	2334.00
IUUC-Oar-090123	Ovis aries	84.66	0.00e+00	2643.00
IUUC-Ptr-090552	Pan troglodytes	80.73	0.00e+00	1068.00
IUUC-Psi-093963	Pelodiscus sinensis	54.72	0.00e+00	1632.00
IUUC-Pfo-096197	Poecilia formosa	34.75	0.00e+00	825.00
IUUC-Pab-097755	Pongo abelii	79.46	0.00e+00	887.00
IUUC-Pca-100809	Procavia capensis	79.90	0.00e+00	1228.00
IUUC-Pva-102554	Pteropus vampyrus	84.29	0.00e+00	2322.00
IUUC-Rno-105174	Rattus norvegicus	70.29	0.00e+00	2081.00
IUUC-Sha-107304	Sarcophilus harrisii	62.02	0.00e+00	1993.00
IUUC-Sar-113168	Sorex araneus	67.08	0.00e+00	1407.00
IUUC-Tru-118251	Takifugu rubripes	36.11	0.00e+00	671.00
IUUC-Tsy-119276	Tarsius syrichta	78.99	9.00e-119	422.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence