iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036867

Ensembl Protein ID

ENSFALP00000003975.1

UniProt Accession

U3JMH1; U3JMH1_FICAL

Genbank Protein ID

ENSFALP00000003975

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01022000

Gene Name

TRIM62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000003809.1	ENSFALT00000003993.1	ENSFALP00000003975.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.00e-06	27.5	6	75
E3 activity/RING/RING	4.60e-07	30.0	11	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk....tcPvtrqplteedlvPnltlrrliqaw 68
            +e+lC+I l + +dPv l + + + r++I ++  +++      cP +r+++ e +l P+l l ++++++
   Q: 6    KDELLCSICLSIYQDPVGLGCEHYFCRRCITEHWVRQEPqgtrDCPECRRTFPEPTLAPSLKLANIVERY 75
           689***************************98885554446679******************99999887 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl+ ++d p+ l+C H f++ C+ ++w+ +    +++  CP Cr
   Q: 11   CSICLSIYQD-PVGLGCEHYFCRRCItEHWVRQE--PQGTRDCPECR 54
           **********.999****************4444..899999****8 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MACSLKDELL CSICLSIYQD PVGLGCEHYF CRRCITEHWV RQEPQGTRDC PECRRTFPEP 60
TLAPSLKLAN IVERYSAFPL DAILGAQRSP FPCKDHEKVK LFCLTDRAVV CFFCDEPAVH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCATTCCTCC CCACCCCAAG TCCCCTCATT CACCCCCTCC CCATCAATCC CCCATTCACA 60
CCCTCAACCC TCTCGCCCTT AACTTCCCCT CACCTCAAGC CCTTATTCAA CCTCTCCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0010719--P:negative regulation of epithelial to mesenchymal transition
GO:0032897--P:negative regulation of viral transcription
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0046596--P:regulation of viral entry into host cell
GO:1902186--P:regulation of viral release from host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002199	Ailuropoda melanoleuca	88.15	0.00e+00	858.00
IUUC-Apl-003767	Anas platyrhynchos	92.43	0.00e+00	830.00
IUUC-Aca-004412	Anolis carolinensis	82.72	0.00e+00	803.00
IUUC-Ame-010927	Astyanax mexicanus	82.95	0.00e+00	843.00
IUUC-Bta-012927	Bos taurus	87.94	0.00e+00	857.00
IUUC-Cja-019317	Callithrix jacchus	82.33	0.00e+00	776.00
IUUC-Cfa-020292	Canis familiaris	88.73	0.00e+00	633.00
IUUC-Cpo-022274	Cavia porcellus	88.47	0.00e+00	638.00
IUUC-Csa-023042	Chlorocebus sabaeus	88.15	0.00e+00	858.00
IUUC-Dre-028493	Danio rerio	81.50	0.00e+00	833.00
IUUC-Dno-030029	Dasypus novemcinctus	83.78	0.00e+00	800.00
IUUC-Dor-031051	Dipodomys ordii	85.68	0.00e+00	815.00
IUUC-Ete-032752	Echinops telfairi	91.11	3.00e-101	362.00
IUUC-Eca-033898	Equus caballus	72.25	0.00e+00	760.00
IUUC-Eeu-034659	Erinaceus europaeus	86.42	6.00e-75	273.00
IUUC-Fca-035492	Felis catus	82.19	0.00e+00	806.00
IUUC-Gmo-038916	Gadus morhua	82.33	0.00e+00	814.00
IUUC-Gga-040360	Gallus gallus	93.76	0.00e+00	896.00
IUUC-Gac-041871	Gasterosteus aculeatus	82.74	0.00e+00	844.00
IUUC-Ggo-044411	Gorilla gorilla	80.95	0.00e+00	794.00
IUUC-Hsa-047025	Homo sapiens	87.53	0.00e+00	886.00
IUUC-Itr-047905	Ictidomys tridecemlineatus	88.15	0.00e+00	858.00
IUUC-Loc-052114	Lepisosteus oculatus	84.20	0.00e+00	855.00
IUUC-Laf-054359	Loxodonta africana	83.55	4.00e-177	613.00
IUUC-Mcc-055563	Macaca mulatta	88.15	0.00e+00	858.00
IUUC-Meu-056027	Macropus eugenii	77.82	2.00e-111	395.00
IUUC-Mga-060146	Meleagris gallopavo	94.64	1.00e-82	298.00
IUUC-Mmr-060822	Microcebus murinus	88.15	0.00e+00	858.00
IUUC-Mdo-062117	Monodelphis domestica	74.41	2.00e-176	611.00
IUUC-Mmu-064086	Mus musculus	87.94	0.00e+00	858.00
IUUC-Mpu-066378	Mustela putorius furo	88.15	0.00e+00	858.00
IUUC-Mlu-067155	Myotis lucifugus	87.18	0.00e+00	870.00
IUUC-Nle-069464	Nomascus leucogenys	88.15	0.00e+00	859.00
IUUC-Opr-071058	Ochotona princeps	90.95	5.00e-123	434.00
IUUC-Ont-071253	Oreochromis niloticus	74.38	0.00e+00	727.00
IUUC-Oan-073614	Ornithorhynchus anatinus	95.57	3.00e-92	329.00
IUUC-Ola-086794	Oryzias latipes	82.54	0.00e+00	838.00
IUUC-Oga-088889	Otolemur garnettii	88.36	0.00e+00	858.00
IUUC-Oar-089203	Ovis aries	84.30	0.00e+00	753.00
IUUC-Ptr-090795	Pan troglodytes	87.73	0.00e+00	888.00
IUUC-Psi-093339	Pelodiscus sinensis	31.38	3.00e-66	245.00
IUUC-Pfo-096942	Poecilia formosa	82.12	0.00e+00	833.00
IUUC-Pab-097936	Pongo abelii	75.71	2.00e-162	564.00
IUUC-Pca-100397	Procavia capensis	87.11	0.00e+00	850.00
IUUC-Ppe-101916	Prunus persica	35.71	1.00e-09	58.90
IUUC-Pva-102293	Pteropus vampyrus	88.41	4.00e-180	623.00
IUUC-Rno-105551	Rattus norvegicus	87.73	0.00e+00	854.00
IUUC-Ssc-115983	Sus scrofa	88.15	0.00e+00	858.00
IUUC-Tgu-117279	Taeniopygia guttata	80.66	0.00e+00	692.00
IUUC-Tru-118238	Takifugu rubripes	82.74	0.00e+00	841.00
IUUC-Tni-119788	Tetraodon nigroviridis	62.29	5.00e-163	566.00
IUUC-Vvi-131261	Vitis vinifera	31.40	1.00e-07	52.40
IUUC-Xtr-132768	Xenopus tropicalis	72.09	0.00e+00	707.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence