iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-060134

UUCD1 version

UUC-MeG-00779

Ensembl Protein ID

ENSMGAP00000000360.2

UniProt Accession

G1MQK2; G1MQK2_MELGA

Protein Name

Uncharacterized protein

Gene Name

UBE2L3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000000959.2	ENSMGAT00000000996.2	ENSMGAP00000000360.2
ENSMGAG00000000959.2	ENSMGAT00000018780.1	ENSMGAP00000018041.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	8.80e-41	138.7	6	140

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           Rl kel+e++k  +++++  +vde++l +w+ li+ p++ pY++g+F++ei+fp +YPfkPPk++f tki+hPn++e+G+vCl ++ ++
   Q: 6    RLLKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVI-SA 92
           899********************************.**************************************************.5* PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           e+W+pa++  +v+ s+++l+++  pe+pl+++ ae+++k+r+++ k+++
   Q: 93   ENWKPATKTDQVIQSLIALVND-XPEHPLRADLAEEYSKDRKKFCKNAE 140
           ********************99.69********************9986 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

TLTSRRLLKE LEEIRKCGMK NFRNIQVDEA NLLTWQGLIV PDNPPYDKGA FRIEINFPAE 60
YPFKPPKITF KTKIYHPNID EKGQVCLPVI SAENWKPATK TDQVIQSLIA LVNDXPEHPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGCTGACCT CCAGGCGTTT GCTGAAACAG AGCTGAGCGT TGTGCCTCGT GTCACTATTA 60
ACTGTTGACT TACTTTGCTT GTTTTCCAGG AGCTTGAAGA AATCCGCAAA TGTGGAATGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0003723--F:RNA binding
GO:0003713--F:transcription coactivator activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0044770--P:cell cycle phase transition
GO:0008283--P:cell proliferation
GO:0071385--P:cellular response to glucocorticoid stimulus
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0070979--P:protein K11-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001446	Ailuropoda melanoleuca	98.23	3.00e-50	189.00
IUUC-Apl-003318	Anas platyrhynchos	96.62	3.00e-70	256.00
IUUC-Aca-005234	Anolis carolinensis	95.42	9.00e-72	261.00
IUUC-Ame-011452	Astyanax mexicanus	92.57	5.00e-66	242.00
IUUC-Bta-012693	Bos taurus	97.95	4.00e-70	255.00
IUUC-Cel-018332	Caenorhabditis elegans	58.00	2.00e-54	204.00
IUUC-Cja-019062	Callithrix jacchus	97.37	2.00e-73	267.00
IUUC-Cfa-020027	Canis familiaris	97.37	2.00e-73	267.00
IUUC-Cpo-022341	Cavia porcellus	97.37	2.00e-73	267.00
IUUC-Csa-023794	Chlorocebus sabaeus	52.98	2.00e-42	164.00
IUUC-Cho-024916	Choloepus hoffmanni	91.00	5.00e-41	158.00
IUUC-Cin-025130	Ciona intestinalis	65.13	4.00e-43	166.00
IUUC-Csv-026183	Ciona savignyi	63.76	3.00e-43	166.00
IUUC-Dre-027710	Danio rerio	92.76	5.00e-69	252.00
IUUC-Dno-029371	Dasypus novemcinctus	98.29	4.00e-52	195.00
IUUC-Dor-031017	Dipodomys ordii	92.11	2.00e-66	243.00
IUUC-Dme-031814	Drosophila melanogaster	74.00	5.00e-65	239.00
IUUC-Ete-032754	Echinops telfairi	97.37	2.00e-73	267.00
IUUC-Eca-034056	Equus caballus	94.08	4.00e-71	259.00
IUUC-Eeu-034942	Erinaceus europaeus	96.05	2.00e-72	264.00
IUUC-Fca-036173	Felis catus	97.37	2.00e-73	267.00
IUUC-Fal-036820	Ficedula albicollis	98.62	2.00e-70	256.00
IUUC-Gmo-038480	Gadus morhua	89.66	1.00e-62	230.00
IUUC-Gga-041039	Gallus gallus	97.37	2.00e-73	267.00
IUUC-Gac-041571	Gasterosteus aculeatus	75.97	1.00e-54	204.00
IUUC-Ggo-044482	Gorilla gorilla	97.96	9.00e-71	258.00
IUUC-Hsa-046287	Homo sapiens	97.37	2.00e-73	267.00
IUUC-Itr-049057	Ictidomys tridecemlineatus	98.53	2.00e-64	236.00
IUUC-Lch-049699	Latimeria chalumnae	81.03	2.00e-41	160.00
IUUC-Loc-052000	Lepisosteus oculatus	90.91	6.00e-67	245.00
IUUC-Laf-053833	Loxodonta africana	97.95	8.00e-70	254.00
IUUC-Mcc-055015	Macaca mulatta	96.05	4.00e-72	262.00
IUUC-Meu-056738	Macropus eugenii	98.02	7.00e-46	174.00
IUUC-Mmr-061002	Microcebus murinus	97.95	2.00e-69	253.00
IUUC-Mdo-062043	Monodelphis domestica	80.00	1.00e-68	251.00
IUUC-Mmu-063615	Mus musculus	97.37	2.00e-73	267.00
IUUC-Mpu-066122	Mustela putorius furo	47.30	2.00e-38	150.00
IUUC-Mlu-067987	Myotis lucifugus	95.39	1.00e-82	297.00
IUUC-Nle-069967	Nomascus leucogenys	94.74	2.00e-82	296.00
IUUC-Opr-070315	Ochotona princeps	97.37	2.00e-73	267.00
IUUC-Ont-072036	Oreochromis niloticus	90.79	3.00e-67	246.00
IUUC-Oan-073297	Ornithorhynchus anatinus	55.45	4.00e-34	135.00
IUUC-Ocu-074565	Oryctolagus cuniculus	97.95	2.00e-70	256.00
IUUC-Ola-086994	Oryzias latipes	81.17	1.00e-70	257.00
IUUC-Oga-088173	Otolemur garnettii	94.67	8.00e-71	258.00
IUUC-Oar-089520	Ovis aries	97.95	4.00e-70	255.00
IUUC-Ptr-090890	Pan troglodytes	96.71	2.00e-83	300.00
IUUC-Pan-092445	Papio anubis	97.96	9.00e-71	258.00
IUUC-Psi-093376	Pelodiscus sinensis	94.77	1.00e-70	258.00
IUUC-Pma-094445	Petromyzon marinus	82.44	4.00e-51	192.00
IUUC-Pfo-096258	Poecilia formosa	90.79	1.00e-66	244.00
IUUC-Pab-097654	Pongo abelii	97.37	2.00e-73	267.00
IUUC-Pca-100712	Procavia capensis	78.29	3.00e-52	196.00
IUUC-Pva-103113	Pteropus vampyrus	98.62	8.00e-70	254.00
IUUC-Rno-104863	Rattus norvegicus	49.33	2.00e-37	147.00
IUUC-Sha-106823	Sarcophilus harrisii	98.58	1.00e-67	247.00
IUUC-Sar-113240	Sorex araneus	98.62	8.00e-70	254.00
IUUC-Ssc-115442	Sus scrofa	97.37	2.00e-73	267.00
IUUC-Tgu-117352	Taeniopygia guttata	97.95	4.00e-70	255.00
IUUC-Tru-117653	Takifugu rubripes	91.45	9.00e-68	248.00
IUUC-Tsy-119345	Tarsius syrichta	98.23	3.00e-50	189.00
IUUC-Tni-119709	Tetraodon nigroviridis	91.45	9.00e-68	248.00
IUUC-Tbe-127451	Tupaia belangeri	91.45	1.00e-78	284.00
IUUC-Ttr-128840	Tursiops truncatus	97.37	2.00e-73	267.00
IUUC-Vpa-130649	Vicugna pacos	53.40	5.00e-31	124.00
IUUC-Xtr-132650	Xenopus tropicalis	94.74	3.00e-71	259.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence