iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022421

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02055341

Gene Name

Usp18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000000556.3	ENSCPOT00000000561.2	ENSCPOP00000000488.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.00e-55	187.7	56	372

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl+N+g tC +NS++Q+ ++ +++++ l++    +++  + +e++ ++  ++  l+e++++s++kav p+el  +l+k ++    + q
   Q: 56   VGLHNIGQTCCLNSLIQVFIMNTDFTKILKR---ITVP--KASEEQRSVPFQMLLLLEKMQDSRQKAVRPTELAYCLQKNNVP--LFVQ 137
           6******************************...3333..33567889********************************998..79** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da  +   + + +++++                          ++    + ++dl+ +++k+ ++cl+c+++ssr+++ l+l+l++ +
   Q: 138  HDAAQLYLTVWNLIKDQI--------------------------TDADLVERLQDLYTIRVKEILVCLDCATESSRDSSLLTLPLSLFD 200
           ******************..........................66778899***********************************98 PP
   S: 179  keetkkesl...qdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspf 264
            +++ +++l   +d+L+ f++ +el+++  ++c++c +k+  ++ lk+++lP++L++hL Rfs   ++++ ek+  ++ fp++Ld  ++
   Q: 201  MNSEPLRTLvgqEDALRYFFQSKELCNKSTCFCQNCGRKTHRKQALKVTRLPQTLTIHLRRFSI--KNSRTEKVCHSLCFPESLDFGQV 287
           8877666654559*************************************************66..567999***************87 PP
   S: 265  cts....peekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg.......staYvlfYkr 337
           + s    +e +++++ +YeL+av+ H+G ++ GHY+ay++n  +gkW++f+Ds+V  v++++++ + g       +taY+l+Y++
   Q: 288  LPSeqpiTEAEEQDEAQYELFAVIAHMGMADFGHYCAYIRNpMDGKWFCFNDSHVCWVSWKDIQCTYGnhgcrwqETAYLLVYMK 372
           777455533444459**************************55677*******************888***************98 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MGMTFGFLGD TCQSTLAESQ QCSGESLEKK GEDSDMKRKR GQPGPLSTWD HHHGLVGLHN 60
IGQTCCLNSL IQVFIMNTDF TKILKRITVP KASEEQRSVP FQMLLLLEKM QDSRQKAVRP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCATGA CGTTTGGGTT CCTGGGAGAC ACCTGCCAGT CAACCTTGGC TGAGTCCCAG 60
CAGTGTTCAG GAGAATCCTT GGAGAAGAAG GGCGAGGACA GCGACATGAA GAGGAAGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0019785--F:ISG15-specific protease activity
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0035634--P:response to stilbenoid
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001615	Ailuropoda melanoleuca	70.59	4.00e-136	477.00
IUUC-Apl-004006	Anas platyrhynchos	57.01	4.00e-97	347.00
IUUC-Aca-005088	Anolis carolinensis	56.62	1.00e-89	323.00
IUUC-Ame-010606	Astyanax mexicanus	34.78	3.00e-41	162.00
IUUC-Bta-013036	Bos taurus	70.90	1.00e-129	455.00
IUUC-Cja-019052	Callithrix jacchus	70.46	1.00e-126	445.00
IUUC-Cfa-020554	Canis familiaris	75.15	2.00e-144	504.00
IUUC-Csa-023737	Chlorocebus sabaeus	71.22	2.00e-79	287.00
IUUC-Cho-024807	Choloepus hoffmanni	62.50	8.00e-57	214.00
IUUC-Dre-027408	Danio rerio	33.84	3.00e-43	168.00
IUUC-Dno-029813	Dasypus novemcinctus	61.32	5.00e-115	407.00
IUUC-Dor-030532	Dipodomys ordii	71.81	8.00e-148	516.00
IUUC-Ete-032254	Echinops telfairi	65.52	1.00e-136	479.00
IUUC-Eca-033482	Equus caballus	76.16	3.00e-138	484.00
IUUC-Eeu-034451	Erinaceus europaeus	66.98	3.00e-78	284.00
IUUC-Fca-036313	Felis catus	70.93	2.00e-144	505.00
IUUC-Fal-037216	Ficedula albicollis	52.50	5.00e-100	357.00
IUUC-Gmo-038649	Gadus morhua	33.33	4.00e-40	158.00
IUUC-Gga-041082	Gallus gallus	51.80	2.00e-90	325.00
IUUC-Gac-042439	Gasterosteus aculeatus	34.58	9.00e-49	187.00
IUUC-Ggo-044957	Gorilla gorilla	73.90	3.00e-112	397.00
IUUC-Hsa-046381	Homo sapiens	72.27	9.00e-154	536.00
IUUC-Itr-047918	Ictidomys tridecemlineatus	74.47	2.00e-158	551.00
IUUC-Loc-052688	Lepisosteus oculatus	34.06	4.00e-45	174.00
IUUC-Laf-054109	Loxodonta africana	73.21	3.00e-156	544.00
IUUC-Mcc-054814	Macaca mulatta	72.87	1.00e-154	539.00
IUUC-Meu-056253	Macropus eugenii	64.48	4.00e-96	344.00
IUUC-Mmr-061613	Microcebus murinus	72.22	1.00e-139	488.00
IUUC-Mdo-061890	Monodelphis domestica	62.68	1.00e-113	402.00
IUUC-Mmu-064329	Mus musculus	69.50	1.00e-142	498.00
IUUC-Mpu-066342	Mustela putorius furo	72.78	1.00e-147	515.00
IUUC-Mlu-067010	Myotis lucifugus	71.66	9.00e-151	526.00
IUUC-Nle-069148	Nomascus leucogenys	71.20	1.00e-149	522.00
IUUC-Opr-070988	Ochotona princeps	69.87	3.00e-63	235.00
IUUC-Ont-072039	Oreochromis niloticus	33.54	4.00e-49	188.00
IUUC-Oan-073740	Ornithorhynchus anatinus	54.96	1.00e-70	259.00
IUUC-Ocu-074498	Oryctolagus cuniculus	73.87	3.00e-146	511.00
IUUC-Ola-086753	Oryzias latipes	35.89	1.00e-46	179.00
IUUC-Oga-088497	Otolemur garnettii	73.48	1.00e-146	512.00
IUUC-Oar-089505	Ovis aries	71.83	5.00e-131	460.00
IUUC-Ptr-091656	Pan troglodytes	72.27	1.00e-154	539.00
IUUC-Pan-092498	Papio anubis	72.87	1.00e-154	539.00
IUUC-Psi-093409	Pelodiscus sinensis	53.78	5.00e-101	360.00
IUUC-Pfo-096507	Poecilia formosa	32.92	2.00e-45	175.00
IUUC-Pab-097828	Pongo abelii	76.09	3.00e-142	497.00
IUUC-Pca-100299	Procavia capensis	70.20	9.00e-91	327.00
IUUC-Pva-102972	Pteropus vampyrus	69.33	2.00e-138	485.00
IUUC-Rno-105738	Rattus norvegicus	68.17	9.00e-143	499.00
IUUC-Sha-107309	Sarcophilus harrisii	60.62	4.00e-104	370.00
IUUC-Sar-112983	Sorex araneus	70.69	3.00e-108	384.00
IUUC-Ssc-116049	Sus scrofa	74.61	8.00e-137	479.00
IUUC-Tgu-117115	Taeniopygia guttata	55.17	1.00e-95	342.00
IUUC-Tru-118022	Takifugu rubripes	30.15	3.00e-40	158.00
IUUC-Tsy-118986	Tarsius syrichta	57.82	2.00e-52	199.00
IUUC-Tni-120306	Tetraodon nigroviridis	32.70	6.00e-41	160.00
IUUC-Tbe-127768	Tupaia belangeri	53.97	7.00e-95	340.00
IUUC-Ttr-128686	Tursiops truncatus	72.22	7.00e-132	463.00
IUUC-Xtr-132032	Xenopus tropicalis	42.41	3.00e-61	228.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence