iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062337

Ensembl Protein ID

ENSMODP00000023990.2

UniProt Accession

H9H7A8; H9H7A8_MONDO

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000019213.2	ENSMODT00000024414.2	ENSMODP00000023990.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.00e-27	92.5	289	320
E3 adaptor/Cullin RING/APC_C/CDC20	7.30e-138	459.1	153	456

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH  +v++l++  d  ll+sG++D+t+ vW+l
   Q: 289  GHRQEVCGLKWsVDhQLLASGGNDNTVLVWSL 320
           8***********6669**************97 PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+k+l+apel++dfylnL+dWs  n+++v+Lgs+ ylw+a+t +v+kl+dl +++d+vtsv+w+e+g+l+avGt+kg v+++Dv++ k 
   Q: 153  PFKILEAPELQNDFYLNLVDWSCLNIITVGLGSRAYLWNAATCQVTKLCDLsSDEDYVTSVNWSEQGNLVAVGTDKGLVQVWDVTAGKM 241
           689************************************************999*********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelkl.stlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfk 176
           + +l+gh arvg L+Wna+++ssG+rd +il+rd+r++  +  + l +h+qevCGlkw+ d++lLasGGnDn+v vw+  + +P++k++
   Q: 242  LCKLEGHAARVGVLAWNADQISSGGRDTMILQRDIRAPRPQSeRWLIGHRQEVCGLKWSVDHQLLASGGNDNTVLVWSLYNVKPVHKYT 330
           *****************************************977789****************************************** PP
   S: 177  ehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkg 265
           +h aavkaiawsP+q++lLasGGGtaDr+i+fwntltg+ +++idtgsqvc+l+ws++ +elvsthG+aen+i++w+ypsl+kva+l g
   Q: 331  KHVAAVKAIAWSPHQHGLLASGGGTADRNIRFWNTLTGQPVQHIDTGSQVCNLAWSRHDNELVSTHGYAENQIAVWRYPSLTKVAKLIG 419
           ***************************************************************************************** PP
   S: 266  heaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           h++Rvl+la+spdg++ivt+agDetlrfw +f k+++
   Q: 420  HSYRVLYLAVSPDGQSIVTGAGDETLRFWTVFYKTHS 456
           ********************************99876 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

RGANMNWSLA LPSSPGSSSN KHGDRFIPSR AGANWGLYFH KPTQPEKSPK QKRKAKQATL 60
DSCPVNPFYT ALLKNELLGA GIENVPHPKG ESQGLQSPIP HTKNLFSYAH NTKRWRPDSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTGGAGCCA ATATGAATTG GAGTCTGGCA CTTCCCAGTT CTCCAGGGTC TTCTTCTAAC 60
AAGCATGGAG ACAGGTTCAT TCCCTCCAGA GCTGGAGCCA ACTGGGGCCT GTACTTCCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID

Species

Identity

E-value

Score

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence