iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004507

UUCD1 version

UUC-AnC-00151

Ensembl Protein ID

ENSACAP00000008064.3

UniProt Accession

H9GDM4; H9GDM4_ANOCA

Protein Name

Uncharacterized protein

Gene Name

RBCK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000008195.3	ENSACAT00000008236.3	ENSACAP00000008064.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.70e-06	26.3	226	269

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadCl..qkwpglknssskefrCPl 44
           C+iC+  +   +g+ +  C H+f++dCl         ns+ +e rCP+
   Q: 226  CPICFVGLeaGEGVTLRECLHAFCKDCLrgTI----LNSQEPEVRCPY 269
           ****99995555588888**********6333....5889*******7 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSTIPIYLKV RPCMTLASLK DMMFLHYGFP PGIQKWVVGQ RLPRDHETLH YHGIQRDGDA 60
AYLYLLSGKA AKLSKDAFEQ EHQRRQLEEL GIKDGILLPR GMAGAAAAAE EDHVVPDHVD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAATATTCA GTTGAATCCA ACGGTACTTA ATCTTTATTT ACATTGCTAT ATACAGTAGC 60
ACTCATTAGC AATAAGTCCT AGACACATGG CAGTGTCTCC TCGGCCACGG AGCAAAAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002867--IBR_dom
IPR029071--Ubiquitin-rel_dom
IPR027370--Znf-RING_LisH
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF13445--zf-RING_UBOX

SMART

SM00547--ZnF_RBZ

Gene Ontology

GO:0071797--C:LUBAC complex
GO:0043130--F:ubiquitin binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060546--P:negative regulation of necroptotic process
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0042346--P:positive regulation of NF-kappaB import into nucleus
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination
GO:0050852--P:T cell receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001540	Ailuropoda melanoleuca	62.56	1.00e-156	545.00
IUUC-Ame-011008	Astyanax mexicanus	53.08	3.00e-133	468.00
IUUC-Bta-013247	Bos taurus	65.20	3.00e-164	571.00
IUUC-Cja-018880	Callithrix jacchus	63.44	3.00e-160	558.00
IUUC-Cfa-020477	Canis familiaris	63.22	5.00e-154	537.00
IUUC-Cpo-021558	Cavia porcellus	63.66	1.00e-160	559.00
IUUC-Csa-024129	Chlorocebus sabaeus	63.22	1.00e-156	546.00
IUUC-Cin-025630	Ciona intestinalis	38.00	4.00e-84	305.00
IUUC-Csv-026069	Ciona savignyi	52.40	3.00e-78	284.00
IUUC-Dno-029015	Dasypus novemcinctus	64.98	2.00e-163	568.00
IUUC-Dor-030313	Dipodomys ordii	57.49	2.00e-140	492.00
IUUC-Ete-032908	Echinops telfairi	53.54	3.00e-127	448.00
IUUC-Eca-034295	Equus caballus	55.51	5.00e-141	494.00
IUUC-Eeu-034454	Erinaceus europaeus	52.21	6.00e-54	204.00
IUUC-Fca-036380	Felis catus	64.10	2.00e-161	561.00
IUUC-Gmo-038561	Gadus morhua	51.78	1.00e-118	419.00
IUUC-Gac-041319	Gasterosteus aculeatus	52.44	7.00e-127	447.00
IUUC-Ggo-044456	Gorilla gorilla	46.87	7.00e-99	354.00
IUUC-Hsa-045738	Homo sapiens	63.22	5.00e-157	547.00
IUUC-Itr-049042	Ictidomys tridecemlineatus	63.66	3.00e-156	545.00
IUUC-Laf-054269	Loxodonta africana	64.76	5.00e-159	553.00
IUUC-Mcc-055669	Macaca mulatta	63.22	2.00e-157	548.00
IUUC-Mmr-061562	Microcebus murinus	63.66	1.00e-154	539.00
IUUC-Mdo-062263	Monodelphis domestica	66.15	4.00e-172	597.00
IUUC-Mmu-064325	Mus musculus	64.54	1.00e-157	549.00
IUUC-Mpu-066385	Mustela putorius furo	63.66	1.00e-159	556.00
IUUC-Mlu-067000	Myotis lucifugus	63.44	1.00e-156	546.00
IUUC-Nle-069812	Nomascus leucogenys	63.66	2.00e-158	551.00
IUUC-Opr-070575	Ochotona princeps	76.96	7.00e-92	330.00
IUUC-Ocu-074358	Oryctolagus cuniculus	56.16	6.00e-137	480.00
IUUC-Oga-087986	Otolemur garnettii	62.33	1.00e-154	539.00
IUUC-Oar-089600	Ovis aries	63.88	2.00e-161	561.00
IUUC-Ptr-091224	Pan troglodytes	63.00	1.00e-156	545.00
IUUC-Pan-092739	Papio anubis	63.44	3.00e-158	551.00
IUUC-Pma-094407	Petromyzon marinus	51.10	2.00e-133	468.00
IUUC-Pab-098627	Pongo abelii	63.00	6.00e-155	540.00
IUUC-Pca-100641	Procavia capensis	63.79	1.00e-147	515.00
IUUC-Pva-102670	Pteropus vampyrus	63.66	4.00e-159	554.00
IUUC-Rno-105504	Rattus norvegicus	65.20	1.00e-158	552.00
IUUC-Sha-107342	Sarcophilus harrisii	66.23	2.00e-173	601.00
IUUC-Ssl-108588	Sclerotinia sclerotiorum	36.54	1.20e-02	34.30
IUUC-Sar-113425	Sorex araneus	70.00	5.00e-92	331.00
IUUC-Ssc-115904	Sus scrofa	79.19	8.00e-84	302.00
IUUC-Tni-119873	Tetraodon nigroviridis	51.32	2.00e-133	469.00
IUUC-Tvi-122601	Trichoderma virens	23.47	2.00e-04	38.90
IUUC-Tbe-127578	Tupaia belangeri	62.73	4.00e-152	530.00
IUUC-Ttr-129107	Tursiops truncatus	63.66	3.00e-157	548.00
IUUC-Vpa-130353	Vicugna pacos	58.98	7.00e-74	270.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence